2-Butyl-3-benzofuranyl 4-(2-(Diethylamino)ethoxy)-3,5-diiodophenyl Ketone Hydrochloride (Amiodarone HCl)

CAS Number: 19774-82-4

Molecular Mass: 681.8 g/mol

Formula: C₂₅H₃₀ClI₂NO₃

Smiles: CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCCN(CC)CC)c(I)c1.Cl

Synonymes:

2-Butyl-3-benzofuranyl 4-(2-(Diethylamino)ethoxy)-3,5-diiodophenyl Ketone Hydrochloride (Amiodarone HCl), Amiodarone hydrochloride, 19774-82-4, Amiodarone HCL, Nexterone, Amiodar, Ritmocardyl, Pacerone, Miodaron, Ortacrone, SKF 33134-A, NSC-85442, DTXSID7037185, SKF-33134-A, L-3428, 976728SY6Z, DTXCID5017185, NSC85442, 2-Butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl ketone hydrochloride, Ketone, 2-butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl, hydrochloride, Amyben, Darmil, Cordarone x, 2-Butyl-3-benzofuranyl 4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone hydrochloride, Ketone, 2-butyl-3-benzofuranyl 4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl, hydrochloride, Cordarone x 100, Cordarone x 200, AMIODARONE HCI, RefChem:54164, NEXTERONE (AMIODARONE HCI), (2-Butylbenzofuran-3-yl)(4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl)methanone monohydrochloride, NSC-343341, VF-236, Trangorex, Amiodarone (hydrochloride), (2-Butylbenzofuran-3-yl)(4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl)methanone hydrochloride, 51087 N HCl, MFCD00069204, Methanone,(2-butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]-,hydrochloride, MLS000028520, Amiodarone hydrochloride [JAN], C25H30ClI2NO3, SMR000058296, (2-Butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone hydrochloride, 2-Butyl-3-benzofuryl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl ketone hydrochloride, Rythmarone, Angoron, Miodrone, Renodoron, Amiodaronum hydrochloride, Methanone, (2-butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]-, hydrochloride (1:1), L 3428 labaz, SR-01000003087, NCGC00015096-12, CAS-19774-82-4, Ancaron, Amio-Aqueous, UNII-976728SY6Z, HSDB 6525, Cordarone (TN), Nexterone (TN), Prestwick_707, Amiodarone hydrochloride [USP:JAN], Ancaron (TN), EINECS 243-293-2, SKF 33134 A, NSC 85442, CPD000058296, 2-[4-(2-butyl-1-benzofuran-3-carbonyl)-2,6-diiodophenoxy]ethyl-diethylazanium, chloride, Opera_ID_568, Amiodarone hydrochloride CRS, SCHEMBL41348, MLS001076313, MLS001424272, MLS002222247, SPECTRUM2300165, AMINODARONE HYDROCHLORIDE, CHEBI:2664, orb1308455, orb3141152, CHEMBL1083993, SCHEMBL29362650, calcium channel (L type) blocker, ITPDYQOUSLNIHG-UHFFFAOYSA-N, GLXC-23127, HMS1569A20, HMS5080L11, Pharmakon1600-02300165, Amiodarone HCl - Bio-X trade mark, Ketone,5-diiodophenyl, hydrochloride, Tox21_113478, Tox21_300395, Tox21_500122, AC-078, AMIODARONE HYDROCHLORIDE [MI], CCG-39607, EBC-07659, HY-14188R, NSC759560, PM-101, s1979, SK&F-33134-A, Amiodarone hydrochloride (JP18/USP), AKOS015844018, Amiodarone (hydrochloride) (Standard), AMIODARONE HYDROCHLORIDE [HSDB], CS-1371, FA17867, KS-5249, LP00122, NC00423, NSC-759560, {2-[4-(2-butyl-1-benzofuran-3-carbonyl)-2,6-diiodophenoxy]ethyl}diethylamine hydrochloride, AMIODARONE HYDROCHLORIDE [MART.], AMIODARONE HYDROCHLORIDE [VANDF], AMIODARONE HYDROCHLORIDE [USP-RS], AMIODARONE HYDROCHLORIDE [WHO-DD], NCGC00093613-01, NCGC00093613-02, NCGC00093613-03, NCGC00093613-04, NCGC00254295-01, NCGC00260807-01, (2-butyl-1-benzofuran-3-yl)-[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone, hydrochloride, BA139263, HY-14188, Methanone, (2-butyl-3-benzofuranyl)(4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl)-, hydrochloride, Methanone,5-diiodophenyl]-, hydrochloride, A2530, EU-0100122, NS00076387, SW196856-4, AMIODARONE HYDROCHLORIDE [ORANGE BOOK], A 8423, AMIODARONE HYDROCHLORIDE [EP MONOGRAPH], AMIODARONE HYDROCHLORIDE [USP MONOGRAPH], D00636, D86460, EN300-123769, F869167, SR-01000003087-2, SR-01000003087-8, WLN: T56 BOJ C4 DVR CI EI DO2N2&2 &GH, Q27271976, Z1554104509, Amiodarone Hydrochloride 1.0 mg/ml in Methanol (as free base), (2-Butylbenzofuran-3-yl)(4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl)methanonehydrochloride, 2-[4-(2-butylbenzofuran-3-carbonyl)-2,6-diiodo-phenoxy]ethyl-diethyl-ammonium, chloride, 2-Butyl-3-benzofuranyl 4-[(2-diethylamino)ethoxy] 3,5-diiodophenyl ketone, hydrochloride, (2-butyl-1-benzofuran-3-yl)-[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone, hydron, chloride, (2-Butyl-1-benzofuran-3-yl){4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}methanone--hydrogen chloride (1/1), 2-Butyl-1-benzofuran-3-yl)-[4-(2-diethylaminoethyloxy)-3,5-diiodophenyl]methanone hydrochloride, METHANONE, (2-BUTYL-3-BENZOFURANYL)(4-(2-(DIETHYLAMINO)ETHOXY)-3,5-DIIODOPHENYL)- HYDROCHLORIDE

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
Ethanol	293.2	-	14.0	[175]
Ethanol	298.0	-	18.45	[174]
Ethanol	298.2	-	18.39	[175]
Ethanol	303.2	-	27.22	[175]
Ethanol	308.2	-	54.03	[175]
Ethanol	310.0	-	67.27	[174]
Ethanol	313.2	-	77.41	[175]
N-Methyl-2-pyrrolidone	293.2	-	66.18	[175]
N-Methyl-2-pyrrolidone	298.2	-	85.9	[175]
N-Methyl-2-pyrrolidone	303.2	-	97.82	[175]
N-Methyl-2-pyrrolidone	308.2	-	123.4	[175]
N-Methyl-2-pyrrolidone	313.2	-	141.7	[175]
Propylene Glycol	298.0	-	28.58	[174]
Propylene Glycol	310.0	-	89.6	[174]
Water	293.2	-	0.1734	[175]
Water	298.0	-	0.23	[174]
Water	298.2	-	0.2431	[175]
Water	303.2	-	0.3152	[175]
Water	308.2	-	0.3595	[175]
Water	310.0	-	0.45	[174]
Water	313.2	-	0.4569	[175]

Molecule 3D descriptors

Descriptor	Value
PMI1	4007.3745
PMI2	10666.9931
PMI3	12961.1237
NPR1	0.3092
NPR2	0.8230
RadiusOfGyration	4.5019
InertialShapeFactor	0.0002
Eccentricity	0.9510
Asphericity	0.3399
SpherocityIndex	0.1030
PBF	0.8614