Sulfadiazine

CAS Number: 68-35-9

Molecular Mass: 250.28 g/mol

Formula: C₁₀H₁₀N₄O₂S

Smiles: Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1

Synonymes:

Sulfadiazine, sulfadiazine, 68-35-9, Sulphadiazine, Sulfapyrimidine, Sulfadiazin, Adiazine, Coco-Diazine, 2-Sulfanilamidopyrimidine, Sulfolex, Benzenesulfonamide, 4-amino-N-2-pyrimidinyl-, 2-Sulfanilylaminopyrimidine, 4-amino-N-pyrimidin-2-ylbenzenesulfonamide, N(1)-2-pyrimidylsulfanilamide, N(sup 1)-2-Pyrimidinylsulfanilamide, 4-amino-N-(pyrimidin-2-yl)benzene-1-sulfonamide, N(1)-2-pyrimidinylsulfanilamide, 4-AMINO-N-2-PYRIMIDINYLBENZENESULFONAMIDE, CHEBI:9328, DTXSID7044130, NSC35600, 0N7609K889, DTXCID5024130, Sulfadiazine, Zinc, Sulfadiazine Base, RefChem:6268, 200-685-8, Sulfacombin, Debenal, Pyrimal, Sulfadiazene, Sulfazine, Adiazin, Cremodiazine, Liquadiazine, Sulfapyrimidin, Diazin, Honey diazine, Spofadrizine, Theradiazine, Cremotres, Deltazina, Diazolone, Eskadiazine, Microsulfon, Neotrizine, Palatrize, Piridisir, Quadetts, Quadramoid, Sanodiazine, Sterazine, Sulfatryl, Sulfonsol, Terfonyl, Trifonamide, Truozine, Neazine, Pirimal, Sulfose, Trisem, Sulfanilamidopyrimidine, Lipo-Levazine, Tri-Sulfameth, Triple Sulfas, Lipo-Diazine, Metha-Meridiazine, Diazovit, Sulfadiazina, Sulphadiazine E, 4-amino-N-(pyrimidin-2-yl)benzenesulfonamide, Sulfadiazinum, Sulfapirimidin, Di-Azo-Mul, Thi-Di-Mer, Codiazine, Pecta-diazine, suspension, RP 2616, Pyrimidine, 2-sulfanilamido-, 2-Sulfapyrimidine, 4-amino-N-pyrimidin-2-yl-benzenesulfonamide, Sulfanilamide, N1-2-pyrimidinyl-, 4-Amino-N-(2-pyrimidinyl)benzenesulfonamide, MFCD00006065, Sulfanilamide, N(sup 1)-2-pyrimidinyl-, 4-Amino-N-2-pyrimidinyl-benzenesulfonamide, N(sup1)-2-Pyrimidylsulfanilamide, Sulfanilamide, N1-2(1H)-pyrimidinylidene-, A-306, N(sup1)-2-Pyrimidinylsulfanilamide, CHEMBL439, S. N. 112, NSC-35600, CAS-68-35-9, NCGC00016305-01, Solfadiazina, TRISULFAPYRIMIDINES (SULFADIAZINE), CocoDiazine, Solfadiazina [DCIT], [(4-aminophenyl)sulfonyl]pyrimidin-2-ylamine, 2-Sulfanilamidopyrimidin, Sulfapyrimidin [German], Benzenesulfonamide, 4-amino-N-(2-pyrimidinyl)-, SDZ, Sulfadiazinum [INN-Latin], Sulfadiazina [INN-Spanish], S.N. 112, 2-Sulfanilamidopyrimidin [German], A-306 (VAN), A 306, SMR000059113, N-(2-Pyrimidinyl)sulfanilamide, rBPI21 & Sulfa, SR-01000002973, EINECS 200-685-8, NSC 35600, 2-Sulfanilamido-pyrimidine, BRN 0235192, diazine, ulfadiazine, CRL-8131 & Sulfadiazine, N1-2-Pyrimidinylsulfanilamide, Sulfadiazine (JAN/USP/INN), Sulfadiazine, , Neotrizine, , AI3-01047, Lantrisul, , Sulfaloid, , Terfonyl, , Sulfose, , Triple Sulfas, , Sulfadiazine CRS, Triple Sulfa, , Trisulfapyrimidine, oral suspension, UNII-0N7609K889, Sulfadiazine [USP:INN:BAN:JAN], Prestwick_428, Sulfonamides Duplex, , RP-2616, Spectrum_000986, Sulfadiazina Reig Jofre, Sulfadiazine (Standard), Sulfacombin (Salt/Mix), Prestwick0_000023, Prestwick1_000023, Prestwick2_000023, Prestwick3_000023, Spectrum2_001319, Spectrum3_001362, Spectrum4_000342, Spectrum5_000992, SULFADIAZINE [MI], SULFADIAZINE [INN], SULFADIAZINE [JAN], Epitope ID:140083, N1-2-Pyrimidylsulfanilamide, Sulfadiazine, >=99.0%, SULFADIAZINE [VANDF], Oprea1_081078, SCHEMBL24176, BSPBio_000085, BSPBio_002884, KBioGR_000743, KBioSS_001466, SULFADIAZINE [MART.], 5-25-10-00067 (Beilstein Handbook Reference), MLS000069423, MLS006011457, 720 - Sulfonamides in fish, DivK1c_000543, pyrimidine, 2-sulphanilamido-, SPECTRUM1500546, SULFADIAZINE [USP-RS], SULFADIAZINE [WHO-DD], SPBio_001417, SPBio_002006, BPBio1_000095, orb1310158, orb3025073, WLN: T6N CNJ BMSWR DZ, GTPL12635, HMS501L05, HY-B0273R, KBio1_000543, KBio2_001466, KBio2_004034, KBio2_006602, KBio3_002104, MSK4017, SULFADIAZINE [GREEN BOOK], NINDS_000543, GLXC-25873, HMS1568E07, HMS1921A13, HMS2090P09, HMS2092I15, HMS2095E07, HMS2235D19, HMS3371L19, HMS3655I10, HMS3712E07, HMS5080A05, Pharmakon1600-01500546, SULFADIAZINE [ORANGE BOOK], SULFADIAZINE [EP MONOGRAPH], SULFADIAZINE [USP IMPURITY], ALBB-014888, HY-B0273, MSK4017-1000DM, SULFADIAZINE [USP MONOGRAPH], Tox21_110360, BBL013169, BDBM50166571, CCG-39257, EBC-03731, MSK4017-100M, NSC757324, Recombinant bactericidal/permeability-increasing protein & Sulfadiazine, s1770, SBB007604, SBB057674, STK317797, SULFOSE COMPONENT SULFADIAZINE, TERFONYL COMPONENT SULFADIAZINE, 2-(p-Aminobenzenesulfonamido)pyrimidin, AKOS000119073, LANTRISUL COMPONENT SULFADIAZINE, SULFALOID COMPONENT SULFADIAZINE, AS29662, DB00359, KS-1144, NSC-757324, 2-(4-Aminobenzenesulfonamido)pyrimidine, 4-amino-N-2-pyrimidylbenzenesulfonamide, IDI1_000543, NEOTRIZINE COMPONENT SULFADIAZINE, NCGC00016305-02, NCGC00016305-03, NCGC00016305-04, NCGC00016305-05, NCGC00016305-06, NCGC00016305-09, NCGC00016305-10, NCGC00016305-11, NCGC00023291-03, NCGC00023291-04, SULFADIAZINE (TRISULFAPYRIMIDINES), 2-(4-Aminobenzenesulfonylamino)pyrimidine, AC-26817, AS182571, ST059447, Sulfadiazine, 100 microg/mL in methanol, Sulfadiazine, Sulfadimidine EP Impurity B, 4-amino-N-2-pyrimidinyl benzenesulfonamide, SBI-0051520.P003, Sulfadiazine 100 microg/mL in Acetonitrile, TRIPLE SULFOID COMPONENT SULFADIAZINE, 4-[[(Pyrimidin-2-yl)amino]sulfonyl]aniline, AB00052095, NS00000198, S0579, ST51006797, Sulfadiazine 1000 microg/mL in Acetonitrile, Sulfadiazine Solution in Methanol, 100ug/mL, SW196657-3, 4-amino-N-(2-pyrimidinyl) benzenesulfonamide, EN300-19076, SULFADIMIDINE IMPURITY B [EP IMPURITY], 4-Amino-N-(2-pyrimidinyl)benzenesulfonamide #, C07658, D00587, D92267, SBI-0051520.0001, Trisulfapyrimidine, oral suspension (Salt/Mix), AB00052095-13, AB00052095-14, AB00052095_15, AB00052095_16, Sulfadiazine, VETRANAL(TM), analytical standard, F358229, F572241, Sulfadiazine for identification of impurity F CRS, Q2555060, SR-01000002973-2, SR-01000002973-3, Sulfadiazine Solution in DMSO/Methanol, 1000ug/mL, BRD-K32273377-001-05-4, BRD-K32273377-001-09-6, BRD-K32273377-001-15-3, BRD-K32273377-001-16-1, BRD-K32273377-001-17-9, 4-AMINO-N-(2-PYRIMIDINYL)-1-BENZENESULFONAMIDE, F1657-1720, Sulfadiazine, certified reference material, TraceCERT(R), TRISULFAPYRIMIDINES (SULFADIAZINE) [ORANGE BOOK], Z104472626, Sulfadiazine, European Pharmacopoeia (EP) Reference Standard, Sulfadiazine, United States Pharmacopeia (USP) Reference Standard, 4-Amino-N-(2-pyrimidinyl)benzenesulfonamide, N1-(Pyrimidin-2-yl)sulfanilamide, Sulfadiazine, Pharmaceutical Secondary Standard, Certified Reference Material, Sulfadiazine for identification of impurity F, European Pharmacopoeia (EP) Reference Standard

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
1-Octanol	298.15	-	0.022	[50]
1-Octanol	303.15	-	0.0282	[50]
1-Octanol	308.15	-	0.0363	[50]
1-Octanol	313.15	-	0.04818	[50]
1-Propanol	293.15	-	0.1298	[51]
1-Propanol	294.15	-	0.3231	[177]
1-Propanol	298.15	-	0.1569	[51]
1-Propanol	298.15	-	0.414	[177]
1-Propanol	303.15	-	0.1945	[51]
1-Propanol	303.15	-	0.5442	[177]
1-Propanol	308.15	-	0.2377	[51]
1-Propanol	308.15	-	0.6875	[177]
1-Propanol	313.15	-	0.2994	[51]
1-Propanol	313.15	-	0.8024	[177]
1-Propanol	318.15	-	0.9111	[177]
Acetone	294.15	-	0.2028	[177]
Acetone	298.15	-	0.2484	[177]
Acetone	303.15	-	0.308	[177]
Acetone	308.15	-	0.3527	[177]
Acetone	313.15	-	0.3787	[177]
Acetone	318.15	-	0.3944	[177]
Acetonitrile	278.15	-	1.539	[178]
Acetonitrile	283.15	-	1.863	[178]
Acetonitrile	288.15	-	2.234	[178]
Acetonitrile	293.15	-	2.539	[178]
Acetonitrile	298.15	-	2.853	[178]
Acetonitrile	303.15	-	3.134	[178]
Acetonitrile	308.15	-	3.621	[178]
Acetonitrile	313.15	-	4.014	[178]
Acetonitrile	318.15	-	4.306	[178]
Chloroform	294.15	-	0.0171	[177]
Chloroform	298.15	-	0.0287	[177]
Chloroform	303.15	-	0.0474	[177]
Chloroform	308.15	-	0.06578	[177]
Chloroform	313.15	-	0.07819	[177]
Chloroform	318.15	-	0.0817	[177]
Ethanol	293.15	-	0.02685	[176]
Ethanol	294.15	-	0.1629	[177]
Ethanol	298.15	-	0.03303	[176]
Ethanol	298.15	-	0.2047	[177]
Ethanol	303.15	-	0.04013	[176]
Ethanol	303.15	-	0.2551	[177]
Ethanol	308.15	-	0.0493	[176]
Ethanol	308.15	-	0.2955	[177]
Ethanol	313.15	-	0.0578	[176]
Ethanol	313.15	-	0.3172	[177]
Ethanol	318.15	-	0.3204	[177]
Ethylene Glycol	278.15	-	1.541	[179]
Ethylene Glycol	283.15	-	1.712	[179]
Ethylene Glycol	288.15	-	1.86	[179]
Ethylene Glycol	293.15	-	2.112	[179]
Ethylene Glycol	298.15	-	2.383	[179]
Ethylene Glycol	303.15	-	2.566	[179]
Ethylene Glycol	308.15	-	2.833	[179]
Ethylene Glycol	313.15	-	3.078	[179]
Ethylene Glycol	318.15	-	3.323	[179]
Isopropanol	294.15	-	0.2132	[177]
Isopropanol	298.15	-	0.266	[177]
Isopropanol	303.15	-	0.3349	[177]
Isopropanol	308.15	-	0.3949	[177]
Isopropanol	313.15	-	0.4303	[177]
Isopropanol	318.15	-	0.4559	[177]
Methanol	278.15	-	0.4466	[178]
Methanol	283.15	-	0.594	[178]
Methanol	288.15	-	0.8205	[178]
Methanol	293.15	-	1.001	[178]
Methanol	294.15	-	1.636	[177]
Methanol	298.15	-	1.173	[178]
Methanol	298.15	-	1.738	[177]
Methanol	303.15	-	1.441	[178]
Methanol	303.15	-	1.901	[177]
Methanol	308.15	-	1.76	[178]
Methanol	308.15	-	2.083	[177]
Methanol	313.15	-	2.051	[178]
Methanol	313.15	-	2.275	[177]
Methanol	318.15	-	2.303	[178]
Methanol	318.15	-	2.451	[177]
N-Methyl-2-pyrrolidone	278.15	-	31.54	[180]
N-Methyl-2-pyrrolidone	283.15	-	36.54	[180]
N-Methyl-2-pyrrolidone	288.15	-	40.7	[180]
N-Methyl-2-pyrrolidone	293.15	-	47.8	[180]
N-Methyl-2-pyrrolidone	298.15	-	51.37	[180]
N-Methyl-2-pyrrolidone	303.15	-	59.26	[180]
N-Methyl-2-pyrrolidone	308.15	-	391.4	[180]
N-Methyl-2-pyrrolidone	313.15	-	407.0	[180]
Propylene Glycol	298.15	-	1.6	[48]
Water	278.15	-	0.02237	[179]
Water	278.15	-	0.02626	[180]
Water	283.15	-	0.02792	[179]
Water	283.15	-	0.03486	[180]
Water	288.15	-	0.0397	[179]
Water	288.15	-	0.04414	[180]
Water	293.15	-	0.00527	[176]
Water	293.15	-	0.0527	[179]
Water	293.15	-	0.05492	[180]
Water	298.15	-	0.0067	[176]
Water	298.15	-	0.06663	[179]
Water	298.15	-	0.07106	[180]
Water	298.15	-	0.0668	[49]
Water	298.15	-	0.06746	[50]
Water	303.15	-	0.009	[176]
Water	303.15	-	0.0898	[179]
Water	303.15	-	0.0874	[180]
Water	303.15	-	0.0857	[49]
Water	303.15	-	0.08272	[50]
Water	308.15	-	0.012	[176]
Water	308.15	-	0.12	[179]
Water	308.15	-	0.1109	[180]
Water	308.15	-	0.1137	[49]
Water	308.15	-	0.1097	[50]
Water	313.15	-	0.01571	[176]
Water	313.15	-	0.1571	[179]
Water	313.15	-	0.1376	[180]
Water	313.15	-	0.1452	[49]
Water	313.15	-	0.1504	[50]
Water	318.15	-	0.1678	[179]
Water	318.15	-	0.1835	[49]
Water	323.15	-	0.2329	[49]
Water	328.15	-	0.2879	[49]
Water	333.15	-	0.358	[49]

Molecule 3D descriptors

Descriptor	Value
PMI1	707.0811
PMI2	1692.1305
PMI3	2087.9826
NPR1	0.3386
NPR2	0.8104
RadiusOfGyration	2.9940
InertialShapeFactor	0.0011
Eccentricity	0.9409
Asphericity	0.3014
SpherocityIndex	0.2397
PBF	0.7881