Terbinafine hydrochloride

CAS Number: 78628-80-5

Molecular Mass: 327.9 g/mol

Formula: C₂₁H₂₆ClN

Smiles: CN(C/C=C/C#CC(C)(C)C)Cc1cccc2ccccc12.Cl

Synonymes:

Terbinafine hydrochloride, 78628-80-5, Terbinafine HCl, Lamisil AT, Bramazil, Bramizil, Muzonal, Terbina, Terbine, NSC-759113, Terbinafine (as hydrochloride), 012C11ZU6G, (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamine hydrochloride, CHEBI:77614, DTXSID90229223, (2E)-N,6,6-TRIMETHYL-N-(NAPHTHALEN-1-YLMETHYL)HEPT-2-EN-4-YN-1-AMINE HYDROCHLORIDE, Shoprite, Curist, Silka, Lamisil once, Athlete's foot, Onycho-Med, Kroger Antifungal, Silka Jock Itch, Lamisil AT Cream, Shopko Athletes Foot, Live Better Antifungal, terbinafin hydrochloride, Terbinafine Hydochloride, RefChem:56104, Curist Antifungal Relief, Cvs Pharmacy Athletes Foot, TERBINAFINE HCL 5%, Terbinafine Tablets 250 mg, DTXCID10151714, Goodsense Terbinafine Hydrochloride, Miconazole Nitrate, Terbinafine Hcl, Terbinafine Hydrochloride 1g in 100g, LAMISIL AT TERBINAFINE HYDROCHLORIDE, (2E)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine monohydrochloride, 691-642-6, Lamisil, (E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine hydrochloride, C21H26ClN, 1-Naphthalenemethanamine, N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-methyl-, hydrochloride (1:1), Zabel, MFCD00145430, CPD000469152, trans-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthylmethylamine Hydrochloride, Lamisil Krem, (E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine, hydrochloride, Terbinafinum [Latin], Terbinafina [Spanish], MycoVa, SF 86-327 hydrochloride, SMR000469152, TDT 067 hydrochloride, DRG-0286, lamosil, Terbisil, Afogan, TerbiFoam, InnoNyx, UNII-012C11ZU6G, Terbinafine HCl?, Lamisil (TN), Terbinafine hydrochloride [USP:JAN], erbinafine hydrochloride, 78628-80-5 (HCl), EC 616-640-4, terbinafine monohydrochloride, SCHEMBL36793, Terbinafine hydrochloride CRS, MLS001066620, MLS001304037, MLS001401424, orb1308695, orb3141391, CHEMBL1200832, SCHEMBL29365335, HTU-520, TRANS-N-(6,6-DIMETHYL-2-HEPTEN-4-YLYL)-N-METHYL-1-NAPHTHYLMETHYLAMINE HYDROCHLORIDE, GLXC-05507, HMS5081H03, Pharmakon1600-01505392, Terbinafine hydrochloride, >=98%, Terbinafine hydrochloride (Lamisil), [(2Z)-6,6-dimethylhept-2-en-4-yn-1-yl](methyl)[(naphthalen-1-yl)methyl]amine hydrochloride, Terbinafine hydrochloride (Standard), AC-761, HY-17395R, MSK000960, NSC759113, s2557, SBB066075, Terbinafine HCl - Bio-X trade mark, TERBINAFINE HYDROCHLORIDE [MI], AKOS015844100, AKOS025149216, Terbinafine for system suitability CRS, Terbinafine hydrochloride (JP18/USP), CCG-101026, CS-1123, FT28039, KS-1289, NC00276, NSC 759113, TERBINAFINE HYDROCHLORIDE [JAN], TERBINAFINE HYDROCHLORIDE [MART.], TERBINAFINE HYDROCHLORIDE [VANDF], 1-Naphthalenemethanamine, N-(6,6-dimethyl-2-hepten-4-ynyl)-N-methyl-, (E)-, monohydrochloride, BT164461, HY-17395, LS-14899, SF-86327, TERBINAFINE HYDROCHLORIDE [USP-RS], TERBINAFINE HYDROCHLORIDE [WHO-DD], NM-100060, D2049, NS00076449, SW197656-2, D02219, TERBINAFINE HYDROCHLORIDE [EP MONOGRAPH], TERBINAFINE HYDROCHLORIDE [ORANGE BOOK], TERBINAFINE HYDROCHLORIDE [USP MONOGRAPH], F332489, Q27147212, n-[(2e)-6,6-dimethyl-2-hepten-4-ynyl]-n-methyl-1-naphthalenemethanamine, Terbinafine hydrochloride, European Pharmacopoeia (EP) Reference Standard, trans-n-methyl-n-(1-naphthylmethyl)-6,6-dimethylhept-2-en-4-ynyl-1-amine, (2E)-N,6,6-trimethyl-N-(1-naphthylmethyl)hept-2-en-4-yn-1-amine hydrochloride, (2E)-N,6,6-Trimethyl-N-(1-naphthylmethyl)hept-2-en-4-yn-1-amine hydrochloride (1:1), (2E)-N,6,6-trimethyl-N-(1-naphthylmethyl)hept-2-en-4-yn-1-aminium chloride, (E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-aminehydrochloride, (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethanamine hydrochloride, [(2E)-6,6-dimethylhept-2-en-4-yn-1-yl](methyl)(naphthalen-1-ylmethyl)amine hydrochloride, [(E)-6,6-dimethylhept-2-en-4-ynyl]-methyl-(naphthalen-1-ylmethyl)azanium, chloride, Terbinafine for system suitability, European Pharmacopoeia (EP) Reference Standard, Terbinafine hydrochloride, Pharmaceutical Secondary Standard, Certified Reference Material, Terbinafine hydrochloride, United States Pharmacopeia (USP) Reference Standard, (2E)-N,6,6-Trimethyl-N-[(naphthalen-1-yl)methyl]hept-2-en-4-yn-1-amine--hydrogen chloride (1/1), (E)-N-(6,6-DIMETHYL-2-HEPTEN-4-YNYL)-N-METHYL-1-NAPHTHALENEMETHYLAMINE, HYDROCHLORIDE, 1-NAPHTHALENEMETHANAMINE, N-(6,6-DIMETHYL-2-HEPTEN-4-YNYL)-N-METHYL-, (E)-, HYDROCHLORIDE

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
1-Butanol	283.15	-	45.14	[216]
1-Butanol	288.15	-	61.38	[216]
1-Butanol	293.15	-	79.3	[216]
1-Butanol	298.15	-	91.82	[216]
1-Butanol	303.15	-	114.6	[216]
1-Butanol	308.15	-	138.5	[216]
1-Butanol	313.15	-	171.8	[216]
1-Butanol	318.15	-	210.7	[216]
1-Butanol	323.15	-	255.9	[216]
1-Hexanol	283.15	-	18.23	[216]
1-Hexanol	288.15	-	24.4	[216]
1-Hexanol	293.15	-	30.6	[216]
1-Hexanol	298.15	-	39.19	[216]
1-Hexanol	303.15	-	49.18	[216]
1-Hexanol	308.15	-	60.72	[216]
1-Hexanol	313.15	-	77.27	[216]
1-Hexanol	318.15	-	99.54	[216]
1-Hexanol	323.15	-	125.8	[216]
1-Pentanol	283.15	-	49.15	[216]
1-Pentanol	288.15	-	64.72	[216]
1-Pentanol	293.15	-	79.17	[216]
1-Pentanol	298.15	-	94.62	[216]
1-Pentanol	303.15	-	111.2	[216]
1-Pentanol	308.15	-	133.8	[216]
1-Pentanol	313.15	-	160.2	[216]
1-Pentanol	318.15	-	189.4	[216]
1-Pentanol	323.15	-	220.8	[216]
1-Propanol	278.15	-	84.75	[215]
1-Propanol	280.65	-	87.58	[215]
1-Propanol	283.15	-	90.27	[215]
1-Propanol	283.15	-	87.78	[216]
1-Propanol	285.65	-	93.13	[215]
1-Propanol	288.15	-	96.21	[215]
1-Propanol	288.15	-	96.39	[216]
1-Propanol	290.65	-	99.31	[215]
1-Propanol	293.15	-	102.4	[215]
1-Propanol	293.15	-	104.8	[216]
1-Propanol	295.65	-	106.1	[215]
1-Propanol	298.15	-	109.5	[215]
1-Propanol	298.15	-	120.9	[216]
1-Propanol	300.65	-	113.2	[215]
1-Propanol	303.15	-	116.9	[215]
1-Propanol	303.15	-	157.9	[216]
1-Propanol	305.65	-	120.7	[215]
1-Propanol	308.15	-	124.5	[215]
1-Propanol	308.15	-	192.7	[216]
1-Propanol	310.65	-	129.1	[215]
1-Propanol	313.15	-	133.2	[215]
1-Propanol	313.15	-	235.3	[216]
1-Propanol	318.15	-	280.1	[216]
1-Propanol	323.15	-	337.3	[216]
2-Butanol	283.15	-	13.4	[216]
2-Butanol	288.15	-	16.93	[216]
2-Butanol	293.15	-	21.82	[216]
2-Butanol	298.15	-	27.5	[216]
2-Butanol	303.15	-	35.62	[216]
2-Butanol	308.15	-	47.19	[216]
2-Butanol	313.15	-	62.56	[216]
2-Butanol	318.15	-	80.76	[216]
2-Butanol	323.15	-	102.3	[216]
Acetonitrile	283.15	-	8.25	[216]
Acetonitrile	288.15	-	9.643	[216]
Acetonitrile	293.15	-	11.2	[216]
Acetonitrile	298.15	-	13.24	[216]
Acetonitrile	303.15	-	15.69	[216]
Acetonitrile	308.15	-	18.65	[216]
Acetonitrile	313.15	-	22.99	[216]
Acetonitrile	318.15	-	27.55	[216]
Acetonitrile	323.15	-	32.02	[216]
Dimethyl sulfoxide	293.15	-	93.72	[216]
Dimethyl sulfoxide	298.15	-	106.4	[216]
Dimethyl sulfoxide	303.15	-	118.4	[216]
Dimethyl sulfoxide	308.15	-	133.0	[216]
Dimethyl sulfoxide	313.15	-	149.4	[216]
Dimethyl sulfoxide	318.15	-	165.5	[216]
Dimethyl sulfoxide	323.15	-	187.7	[216]
Ethanol	278.15	-	108.9	[215]
Ethanol	280.65	-	114.3	[215]
Ethanol	283.15	-	120.1	[215]
Ethanol	283.15	-	115.0	[216]
Ethanol	285.65	-	125.9	[215]
Ethanol	288.15	-	132.5	[215]
Ethanol	288.15	-	128.2	[216]
Ethanol	290.65	-	139.2	[215]
Ethanol	293.15	-	146.3	[215]
Ethanol	293.15	-	141.4	[216]
Ethanol	295.65	-	153.1	[215]
Ethanol	298.15	-	160.5	[215]
Ethanol	298.15	-	172.0	[216]
Ethanol	300.65	-	168.3	[215]
Ethanol	303.15	-	177.3	[215]
Ethanol	303.15	-	196.7	[216]
Ethanol	305.65	-	186.9	[215]
Ethanol	308.15	-	195.9	[215]
Ethanol	308.15	-	238.8	[216]
Ethanol	310.65	-	205.9	[215]
Ethanol	313.15	-	216.2	[215]
Ethanol	313.15	-	284.9	[216]
Ethanol	318.15	-	331.4	[216]
Ethanol	323.15	-	395.0	[216]
Ethyl acetate	278.15	-	7.54	[215]
Ethyl acetate	280.65	-	8.722	[215]
Ethyl acetate	283.15	-	10.36	[215]
Ethyl acetate	285.65	-	12.22	[215]
Ethyl acetate	288.15	-	14.13	[215]
Ethyl acetate	290.65	-	16.28	[215]
Ethyl acetate	293.15	-	18.76	[215]
Ethyl acetate	295.65	-	21.04	[215]
Ethyl acetate	298.15	-	23.99	[215]
Ethyl acetate	300.65	-	27.45	[215]
Ethyl acetate	303.15	-	30.66	[215]
Ethyl acetate	305.65	-	34.99	[215]
Ethyl acetate	308.15	-	39.41	[215]
Ethyl acetate	310.65	-	44.09	[215]
Ethyl acetate	313.15	-	49.54	[215]
Isoamyl Alcohol	283.15	-	22.3	[216]
Isoamyl Alcohol	288.15	-	28.73	[216]
Isoamyl Alcohol	293.15	-	35.82	[216]
Isoamyl Alcohol	298.15	-	45.13	[216]
Isoamyl Alcohol	303.15	-	57.46	[216]
Isoamyl Alcohol	308.15	-	73.54	[216]
Isoamyl Alcohol	313.15	-	90.69	[216]
Isoamyl Alcohol	318.15	-	118.9	[216]
Isoamyl Alcohol	323.15	-	151.4	[216]
Isobutanol	283.15	-	36.51	[216]
Isobutanol	288.15	-	46.07	[216]
Isobutanol	293.15	-	57.4	[216]
Isobutanol	298.15	-	76.89	[216]
Isobutanol	303.15	-	99.61	[216]
Isobutanol	308.15	-	128.4	[216]
Isobutanol	313.15	-	164.1	[216]
Isobutanol	318.15	-	204.9	[216]
Isobutanol	323.15	-	256.4	[216]
Isopropanol	283.15	-	13.5	[216]
Isopropanol	288.15	-	16.92	[216]
Isopropanol	293.15	-	20.98	[216]
Isopropanol	298.15	-	26.89	[216]
Isopropanol	303.15	-	35.52	[216]
Isopropanol	308.15	-	45.34	[216]
Isopropanol	313.15	-	61.15	[216]
Isopropanol	318.15	-	77.6	[216]
Isopropanol	323.15	-	104.1	[216]
Methanol	278.15	-	342.0	[215]
Methanol	280.65	-	352.4	[215]
Methanol	283.15	-	362.7	[215]
Methanol	285.65	-	374.7	[215]
Methanol	288.15	-	386.7	[215]
Methanol	290.65	-	400.2	[215]
Methanol	293.15	-	413.7	[215]
Methanol	295.65	-	426.8	[215]
Methanol	298.15	-	439.9	[215]
Methanol	300.65	-	454.5	[215]
Methanol	303.15	-	469.1	[215]
Methanol	305.65	-	483.6	[215]
Methanol	308.15	-	498.2	[215]
Methanol	310.65	-	514.6	[215]
Methanol	313.15	-	531.0	[215]

Molecule 3D descriptors

Descriptor	Value
PMI1	785.9045
PMI2	5507.6304
PMI3	5801.5942
NPR1	0.1355
NPR2	0.9493
RadiusOfGyration	4.2946
InertialShapeFactor	0.0012
Eccentricity	0.9908
Asphericity	0.6499
SpherocityIndex	0.1851
PBF	0.8911