Zonisamide

CAS Number: 68291-97-4

Molecular Mass: 212.23 g/mol

Formula: C₈H₈N₂O₃S

Smiles: NS(=O)(=O)Cc1noc2ccccc12

Synonymes:

Zonisamide, zonisamide, 68291-97-4, Zonegran, 1,2-Benzisoxazole-3-methanesulfonamide, 1,2-benzoxazol-3-ylmethanesulfonamide, Exceglan, Excegram, Excegran, AD-810, Zonisamida, Zonisamidum, CI-912, 3-(Sulfamoylmethyl)-1,2-benzisoxazole, PD-110843, ZONISADE, DTXSID9046023, N03AX15, Benzo[d]isoxazol-3-yl-methanesulfonamide, 459384H98V, DTXCID7026023, CHEBI:10127, 1,2-Benzisoxazol-3-ylmethanesulfonamide, Benzo(d)isoxazol-3-yl-methanesulfonamide, AD810, CI912, 3 Sulfamoylmethyl 1,2 benzisoxazole, RefChem:57626, 614-395-8, Zonisamidum [Latin], Zonisamida [Spanish], benzo[d]isoxazol-3-ylmethanesulfonamide, AD 810, PD 110843, 1-(1,2-Benzoxazol-3-Yl)methanesulfonamide, MFCD00865316, CHEMBL750, SPR_2, 1-(1,2-benzisoxazol-3-yl)methanesulfonamide, s1445, NCGC00159319-02, NCGC00159319-04, Trerief, Tremode, Excegran (TN), SMR000596519, Zonisamide (ZNS), CAS-68291-97-4, HSDB 7293, SR-01000837537, BRN 1077076, Fenisoxine, Excegran, , Exegran, , Exogran, , Zonisamide, ZNS, AD-810N, Zonisamide, 1, UNII-459384H98V, Zonisamide [USAN:USP:INN:BAN:JAN], Zonisamide (Standard), (1,2-benzoxazol-3-yl)methanesulfonamide, ZONISAMIDE [MI], ZONISAMIDE [INN], ZONISAMIDE [JAN], ZONISAMIDE [HSDB], ZONISAMIDE [USAN], ZONISAMIDE [VANDF], E-2090, ZONISAMIDE [MART.], ZONISAMIDE [USP-RS], ZONISAMIDE [WHO-DD], BIDD:PXR0183, SCHEMBL35458, MLS001195632, MLS001306491, BIDD:GT0708, ZONISAMIDE [EMA EPAR], GTPL7047, orb1310776, orb3141298, Zonisamide (JP18/USP/INN), SCHEMBL29358822, ZONISAMIDE [ORANGE BOOK], BDBM10888, HY-B0124R, Zonisamide - Bio-X trade mark, HMS2089O07, HMS2235L13, HMS3259N09, HMS3269F21, HMS3413L09, HMS3657E03, HMS3677L09, HMS3714E19, HMS3742M15, HMS3884I17, HMS5079O06, ZONISAMIDE [USP MONOGRAPH], Zonisamide 1.0 mg/ml in Methanol, HY-B0124, MSK10526, Tox21_111569, BBL010040, EBC-11182, HB0675, SBB070483, STK711131, AKOS001312269, Tox21_111569_1, AC-1413, CCG-220669, CS-1888, DB00909, FB28784, KS-1142, NC00637, NCGC00159319-03, BZ164593, 1,?2-?Benzisoxazole-?3-?methanesulfonamide, NS00000539, SW199135-2, Z0026, EN300-50288, C07504, C76163, D00538, AB00876297-09, AB00876297-10, AB00876297_11, Zonisamide pound>>CI-912 pound>>PD 110843, F358363, Q219957, SR-01000837537-2, SR-01000837537-3, SR-01000837537-8, BRD-K48300629-001-03-8, BRD-K48300629-001-13-7, BRD-K48300629-001-14-5, Z223042524

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
1,4-Dioxane	288.15	-	61.74	[273]
1,4-Dioxane	293.15	-	75.52	[273]
1,4-Dioxane	298.15	-	90.79	[273]
1,4-Dioxane	303.15	-	107.0	[273]
1,4-Dioxane	308.15	-	125.7	[273]
1,4-Dioxane	313.15	-	145.2	[273]
1-Butanol	273.15	-	0.402	[273]
1-Butanol	278.15	-	0.611	[273]
1-Butanol	283.15	-	0.8966	[273]
1-Butanol	288.15	-	1.23	[273]
1-Butanol	293.15	-	1.673	[273]
1-Butanol	298.15	-	2.19	[273]
1-Butanol	303.15	-	2.805	[273]
1-Butanol	308.15	-	3.394	[273]
1-Butanol	313.15	-	4.061	[273]
1-Propanol	273.15	-	1.19	[273]
1-Propanol	278.15	-	1.574	[273]
1-Propanol	283.15	-	2.0	[273]
1-Propanol	288.15	-	2.46	[273]
1-Propanol	293.15	-	2.994	[273]
1-Propanol	298.15	-	3.565	[273]
1-Propanol	303.15	-	4.204	[273]
1-Propanol	308.15	-	4.897	[273]
1-Propanol	313.15	-	5.57	[273]
Acetonitrile	273.15	-	23.48	[273]
Acetonitrile	278.15	-	28.37	[272]
Acetonitrile	278.15	-	28.74	[273]
Acetonitrile	283.15	-	33.15	[272]
Acetonitrile	283.15	-	33.94	[273]
Acetonitrile	288.15	-	38.52	[272]
Acetonitrile	288.15	-	40.39	[273]
Acetonitrile	293.15	-	44.32	[272]
Acetonitrile	293.15	-	46.72	[273]
Acetonitrile	298.15	-	50.38	[272]
Acetonitrile	298.15	-	53.47	[273]
Acetonitrile	303.15	-	57.56	[272]
Acetonitrile	303.15	-	60.35	[273]
Acetonitrile	308.15	-	65.03	[272]
Acetonitrile	308.15	-	68.76	[273]
Acetonitrile	313.15	-	73.45	[272]
Acetonitrile	313.15	-	76.35	[273]
Acetonitrile	318.15	-	82.59	[272]
Acetonitrile	323.15	-	92.35	[272]
Cyclohexanone	273.15	-	15.55	[273]
Cyclohexanone	278.15	-	18.85	[273]
Cyclohexanone	283.15	-	22.8	[273]
Cyclohexanone	288.15	-	26.99	[273]
Cyclohexanone	293.15	-	32.35	[273]
Cyclohexanone	298.15	-	38.19	[273]
Cyclohexanone	303.15	-	45.09	[273]
Cyclohexanone	308.15	-	54.3	[273]
Cyclohexanone	313.15	-	63.49	[273]
Dimethylformamide	273.15	-	55.12	[273]
Dimethylformamide	278.15	-	84.16	[272]
Dimethylformamide	278.15	-	80.1	[273]
Dimethylformamide	283.15	-	102.7	[272]
Dimethylformamide	283.15	-	108.1	[273]
Dimethylformamide	288.15	-	123.8	[272]
Dimethylformamide	288.15	-	136.1	[273]
Dimethylformamide	293.15	-	149.3	[272]
Dimethylformamide	293.15	-	168.2	[273]
Dimethylformamide	298.15	-	178.9	[272]
Dimethylformamide	298.15	-	202.2	[273]
Dimethylformamide	303.15	-	211.7	[272]
Dimethylformamide	303.15	-	240.8	[273]
Dimethylformamide	308.15	-	252.5	[272]
Dimethylformamide	308.15	-	283.6	[273]
Dimethylformamide	313.15	-	301.5	[272]
Dimethylformamide	313.15	-	325.4	[273]
Dimethylformamide	318.15	-	360.2	[272]
Dimethylformamide	323.15	-	421.8	[272]
Ethanol	273.15	-	4.165	[273]
Ethanol	278.15	-	5.139	[272]
Ethanol	278.15	-	4.991	[273]
Ethanol	283.15	-	5.947	[272]
Ethanol	283.15	-	5.863	[273]
Ethanol	288.15	-	6.788	[272]
Ethanol	288.15	-	6.872	[273]
Ethanol	293.15	-	7.819	[272]
Ethanol	293.15	-	8.067	[273]
Ethanol	298.15	-	8.876	[272]
Ethanol	298.15	-	9.247	[273]
Ethanol	303.15	-	10.07	[272]
Ethanol	303.15	-	10.46	[273]
Ethanol	308.15	-	11.34	[272]
Ethanol	308.15	-	11.84	[273]
Ethanol	313.15	-	12.7	[272]
Ethanol	313.15	-	13.33	[273]
Ethanol	318.15	-	14.19	[272]
Ethanol	323.15	-	15.75	[272]
Ethyl acetate	273.15	-	11.14	[273]
Ethyl acetate	278.15	-	12.41	[273]
Ethyl acetate	283.15	-	13.84	[273]
Ethyl acetate	288.15	-	15.47	[273]
Ethyl acetate	293.15	-	17.33	[273]
Ethyl acetate	298.15	-	19.17	[273]
Ethyl acetate	303.15	-	21.18	[273]
Ethyl acetate	308.15	-	23.25	[273]
Ethyl acetate	313.15	-	25.3	[273]
Isopropanol	273.15	-	1.751	[273]
Isopropanol	278.15	-	2.248	[272]
Isopropanol	278.15	-	2.233	[273]
Isopropanol	283.15	-	2.704	[272]
Isopropanol	283.15	-	2.797	[273]
Isopropanol	288.15	-	3.206	[272]
Isopropanol	288.15	-	3.402	[273]
Isopropanol	293.15	-	3.803	[272]
Isopropanol	293.15	-	4.051	[273]
Isopropanol	298.15	-	4.517	[272]
Isopropanol	298.15	-	4.775	[273]
Isopropanol	303.15	-	5.287	[272]
Isopropanol	303.15	-	5.681	[273]
Isopropanol	308.15	-	6.184	[272]
Isopropanol	308.15	-	6.598	[273]
Isopropanol	313.15	-	7.191	[272]
Isopropanol	313.15	-	7.459	[273]
Isopropanol	318.15	-	8.279	[272]
Isopropanol	323.15	-	9.478	[272]
Methanol	273.15	-	13.63	[273]
Methanol	278.15	-	14.65	[273]
Methanol	283.15	-	15.87	[273]
Methanol	288.15	-	17.23	[273]
Methanol	293.15	-	18.58	[273]
Methanol	298.15	-	20.23	[273]
Methanol	303.15	-	21.89	[273]
Methanol	308.15	-	23.8	[273]
Methanol	313.15	-	25.7	[273]
Methyl ethyl ketone	273.15	-	32.4	[273]
Methyl ethyl ketone	278.15	-	37.8	[273]
Methyl ethyl ketone	283.15	-	43.8	[273]
Methyl ethyl ketone	288.15	-	50.92	[273]
Methyl ethyl ketone	293.15	-	59.39	[273]
Methyl ethyl ketone	298.15	-	68.38	[273]
Methyl ethyl ketone	303.15	-	77.06	[273]
Methyl ethyl ketone	308.15	-	86.25	[273]
Methyl ethyl ketone	313.15	-	95.99	[273]
Toluene	273.15	-	0.07254	[273]
Toluene	278.15	-	0.1025	[273]
Toluene	283.15	-	0.1359	[273]
Toluene	288.15	-	0.1745	[273]
Toluene	293.15	-	0.2115	[273]
Toluene	298.15	-	0.2608	[273]
Toluene	303.15	-	0.3155	[273]
Toluene	308.15	-	0.3798	[273]
Toluene	313.15	-	0.4491	[273]
Water	278.15	-	0.21	[272]
Water	283.15	-	0.294	[272]
Water	288.15	-	0.404	[272]
Water	293.15	-	0.5498	[272]
Water	298.15	-	0.7622	[272]
Water	303.15	-	1.005	[272]
Water	308.15	-	1.316	[272]
Water	313.15	-	1.748	[272]
Water	318.15	-	2.289	[272]
Water	323.15	-	2.984	[272]

Molecule 3D descriptors

Descriptor	Value
PMI1	365.6008
PMI2	1241.5616
PMI3	1451.0843
NPR1	0.2520
NPR2	0.8556
RadiusOfGyration	2.6842
InertialShapeFactor	0.0023
Eccentricity	0.9677
Asphericity	0.4254
SpherocityIndex	0.2236
PBF	0.6473