Indapamide

CAS Number: 26807-65-8

Molecular Mass: 365.8 g/mol

Formula: C₁₆H₁₆ClN₃O₃S

Smiles: CC1Cc2ccccc2N1NC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1

Synonymes:

Indapamide, indapamide, 26807-65-8, Veroxil, Indamol, Noranat, Fludex, Lozol, Tertensif, Arifon, Indaflex, Ipamix, Tandix, Bajaten, Natrilix, Damide, Indapamida, Metindamide, Natrix, flupamid, indamide, Indapamidum, SE-1520, Fludin, Lorvas, S-1520, FLUBEST, SE 1520, 4-chloro-N-(2-methyl-2,3-dihydroindol-1-yl)-3-sulfamoylbenzamide, 4-Chloro-N-(2-methyl-1-indolinyl)-3-sulfamoylbenzamide, Benzamide, 3-(aminosulfonyl)-4-chloro-N-(2,3-dihydro-2-methyl-1H-indol-1-yl)-, NSC-757075, DTXSID7044633, 4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-sulfamoylbenzamide, Ethibide xl, Natrilix sr, Cardide sr, Indipam xl, Mapemid xl, Tensaid xl, KYD-041, Varbim xl, Rawel xl, Nindaxa 2.5, Opumide 2.5, Indaxa 2.5, F089I0511L, CHEBI:5893, DTXCID5024633, S1520, SE1520, RefChem:58774, S 1520, C03BA11, 4-Chloro-N-((2RS)-2-methyl-2,3-dihydro-1H-indol-1-yl)-3-sulfamoylbenzamide, 248-012-7, Pressurai, Indapamidum [INN-Latin], Indapamida [INN-Spanish], 1-(4-Chloro-3-sulfamoylbenzamido)-2-methylindoline, Indapamide (Lozol), 3-(Aminosulfonyl)-4-chloro-N-(2,3-dihydro-2-methyl-1H-indol-1-yl)benzamide, N-(4-Chloro-3-sulfamoylbenzamido)-2-methylindoline, MFCD00079375, Cormil, RAC INDAPAMIDE, MLS000028554, BENZAMIDE, 4-CHLORO-N-(2-METHYL-1-INDOLINYL)-3-SULFAMOYL-, NCGC00018172-03, SMR000058829, 4-CHLORO-N-(2-METHYLINDOLIN-1-YL)-3-SULFAMOYLBENZAMIDE, RHC 2555, USV 2555, Natrix (TN), Lozol (TN), SR-01000003079, EINECS 248-012-7, BRN 1604026, Indapamide CRS, UNII-F089I0511L, 26807-65-8(free base), Hypen SR, Racemi c indapamide, Indapamide [USAN:USP:INN:BAN:JAN], Indapamide (Standard), Spectrum_000917, INDAPAMIDE [MI], Opera_ID_110, INDAPAMIDE [INN], INDAPAMIDE [JAN], Prestwick3_000220, Spectrum2_000980, Spectrum3_000467, Spectrum4_000017, Spectrum5_000866, INDAPAMIDE [USAN], INDAPAMIDE [VANDF], CHEMBL406, Indapamide (JP18/USP), INDAPAMIDE [MART.], INDAPAMIDE [USP-RS], INDAPAMIDE [WHO-DD], SCHEMBL41303, Widaplik component Indapamide, BSPBio_000239, BSPBio_002174, KBioGR_000393, KBioSS_001397, 5-20-06-00348 (Beilstein Handbook Reference), MLS001148152, MLS002222229, MLS006011900, orb134441, DivK1c_000508, SPECTRUM1500349, SPBio_001019, BPBio1_000263, BR-1015 component Indapamide, GTPL7203, Indapamide - Bio-X trade mark, INDAPAMIDE [ORANGE BOOK], SCHEMBL29372690, SCHEMBL29377544, BDBM25901, HMS501J10, HY-B0259R, KBio1_000508, KBio2_001397, KBio2_003965, KBio2_006533, KBio3_001394, 4-chloro-N-(2-methylindolin-1-yl)-3-sulfamoyl-benzamide, INDAPAMIDE [EP MONOGRAPH], Indapamide component of br-1015, NINDS_000508, HMS1920F19, HMS2090M16, HMS2091N07, HMS2095L21, HMS2231G13, HMS3259C14, HMS3369J20, HMS3655E06, HMS3712L21, HMS3748K05, HMS5079N18, INDAPAMIDE [USP MONOGRAPH], Pharmakon1600-01500349, Indapamide 1.0 mg/ml in Methanol, HY-B0259, MSK10493, Tox21_110775, Tox21_113182, Tox21_302687, CCG-40198, EBC-06876, NSC757075, s1730, STL257105, STL455045, 3-(Aminosulfonyl)-4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)benzamide, AKOS015888148, Tox21_110775_1, AB03037, AC-2073, DB00808, FI01202, KS-5219, NC00568, NSC 757075, Benzamide, 3-(aminosulfonyl)-4-chloro-N-(2,3-dihydro-2-methyl-1H-indol-l-yl)-, IDI1_000508, NCGC00018172-02, NCGC00018172-04, NCGC00018172-06, NCGC00018172-08, NCGC00018172-09, NCGC00089727-02, NCGC00089727-03, NCGC00256884-01, BI300090, SBI-0051415.P003, DB-047020, AB00052021, I0730, NS00000696, ST51015024, SW198686-2, D00345, EN300-117260, AB00052021-14, AB00052021-15, AB00052021_16, AB00052021_17, Indapamide, analytical standard, for drug analysis, Q1078392, SR-01000003079-2, SR-01000003079-3, BRD-A95869247-001-04-6, BRD-A95869247-001-14-5, BRD-A95869247-001-25-1, BRD-A95869247-001-26-9, Z1501485351, Indapamide, British Pharmacopoeia (BP) Reference Standard, Indapamide, European Pharmacopoeia (EP) Reference Standard, (4-chloro-3-sulfamoylphenyl)-N-(2-methylindolinyl)carboxamide, Indapamide, United States Pharmacopeia (USP) Reference Standard, 3-aminosulfonyl-4-chloro-N-(2,3-dihydro-2-methyl-1H-indol-1-yl)benzamide, 4-chloro-3-aminosulphonyl-N-(2,3-dihydro2-methyl-1H-indol-1-yl)benzamide, Indapamide, Pharmaceutical Secondary Standard, Certified Reference Material, 3-(aminosulphonyl)-4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1--yl)benzamide, 3-(aminosulphonyl)-4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)benzamide, 4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-sulfamoylbenzenecarboximidic acid

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
1-Propanol	278.15	-	14.2	[284]
1-Propanol	283.15	-	19.73	[284]
1-Propanol	288.15	-	26.25	[284]
1-Propanol	293.15	-	33.73	[284]
1-Propanol	298.15	-	43.39	[284]
1-Propanol	303.15	-	55.75	[284]
1-Propanol	308.15	-	69.9	[284]
1-Propanol	313.15	-	86.37	[284]
1-Propanol	318.15	-	106.8	[284]
Acetone	278.15	-	106.0	[284]
Acetone	283.15	-	117.8	[284]
Acetone	288.15	-	132.4	[284]
Acetone	293.15	-	147.7	[284]
Acetone	298.15	-	164.5	[284]
Acetone	303.15	-	183.0	[284]
Acetone	308.15	-	203.9	[284]
Acetone	313.15	-	224.9	[284]
Acetone	318.15	-	249.9	[284]
Acetonitrile	278.15	-	13.11	[284]
Acetonitrile	283.15	-	19.71	[284]
Acetonitrile	288.15	-	27.54	[284]
Acetonitrile	293.15	-	37.59	[284]
Acetonitrile	298.15	-	49.77	[284]
Acetonitrile	303.15	-	66.09	[284]
Acetonitrile	308.15	-	85.47	[284]
Acetonitrile	313.15	-	108.8	[284]
Acetonitrile	318.15	-	136.8	[284]
Cyclohexane	278.15	-	0.0044	[284]
Cyclohexane	283.15	-	0.008	[284]
Cyclohexane	288.15	-	0.0128	[284]
Cyclohexane	293.15	-	0.0199	[284]
Cyclohexane	298.15	-	0.0313	[284]
Cyclohexane	303.15	-	0.0486	[284]
Cyclohexane	308.15	-	0.0741	[284]
Cyclohexane	313.15	-	0.1111	[284]
Cyclohexane	318.15	-	0.1647	[284]
Ethanol	278.15	-	24.51	[284]
Ethanol	283.15	-	32.75	[284]
Ethanol	288.15	-	44.97	[284]
Ethanol	293.15	-	57.78	[284]
Ethanol	298.15	-	73.06	[284]
Ethanol	303.15	-	93.4	[284]
Ethanol	308.15	-	116.6	[284]
Ethanol	313.15	-	142.7	[284]
Ethanol	318.15	-	172.4	[284]
Ethyl acetate	278.15	-	1.736	[284]
Ethyl acetate	283.15	-	2.916	[284]
Ethyl acetate	288.15	-	4.329	[284]
Ethyl acetate	293.15	-	6.179	[284]
Ethyl acetate	298.15	-	8.751	[284]
Ethyl acetate	303.15	-	12.43	[284]
Ethyl acetate	308.15	-	17.07	[284]
Ethyl acetate	313.15	-	23.36	[284]
Ethyl acetate	318.15	-	31.14	[284]
Isopropanol	278.15	-	5.855	[284]
Isopropanol	283.15	-	9.073	[284]
Isopropanol	288.15	-	13.46	[284]
Isopropanol	293.15	-	18.53	[284]
Isopropanol	298.15	-	25.58	[284]
Isopropanol	303.15	-	34.85	[284]
Isopropanol	308.15	-	46.5	[284]
Isopropanol	313.15	-	61.78	[284]
Isopropanol	318.15	-	79.63	[284]
Methanol	278.15	-	48.43	[284]
Methanol	283.15	-	62.23	[284]
Methanol	288.15	-	80.42	[284]
Methanol	293.15	-	104.8	[284]
Methanol	298.15	-	133.9	[284]
Methanol	303.15	-	170.2	[284]
Methanol	308.15	-	208.5	[284]
Methanol	313.15	-	250.3	[284]
Methanol	318.15	-	299.2	[284]
Methyl ethyl ketone	278.15	-	65.59	[284]
Methyl ethyl ketone	283.15	-	73.9	[284]
Methyl ethyl ketone	288.15	-	83.11	[284]
Methyl ethyl ketone	293.15	-	93.97	[284]
Methyl ethyl ketone	298.15	-	106.2	[284]
Methyl ethyl ketone	303.15	-	120.7	[284]
Methyl ethyl ketone	308.15	-	136.4	[284]
Methyl ethyl ketone	313.15	-	153.2	[284]
Methyl ethyl ketone	318.15	-	171.8	[284]
Toluene	278.15	-	0.0152	[284]
Toluene	283.15	-	0.0223	[284]
Toluene	288.15	-	0.0374	[284]
Toluene	293.15	-	0.0576	[284]
Toluene	298.15	-	0.087	[284]
Toluene	303.15	-	0.1232	[284]
Toluene	308.15	-	0.1765	[284]
Toluene	313.15	-	0.2532	[284]
Toluene	318.15	-	0.354	[284]

Molecule 3D descriptors

Descriptor	Value
PMI1	1228.5358
PMI2	5263.7653
PMI3	5687.1203
NPR1	0.2160
NPR2	0.9256
RadiusOfGyration	4.0799
InertialShapeFactor	0.0008
Eccentricity	0.9764
Asphericity	0.4900
SpherocityIndex	0.2628
PBF	1.0512