Nefopam hydrochloride

CAS Number: 23327-57-3

Molecular Mass: 289.8 g/mol

Formula: C₁₇H₂₀ClNO

Smiles: CN1CCOC(c2ccccc2)c2ccccc2C1.Cl

Synonymes:

Nefopam hydrochloride, 23327-57-3, Nefopam HCl, Acupan, DTXSID7045441, 3,4,5,6-Tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine hydrochloride, 685J48E13W, NSC-757856, DTXCID5025441, 1H-2,5-Benzoxazocine, 3,4,5,6-tetrahydro-5-methyl-1-phenyl-, hydrochloride, Hydrochloride, Nefopam, RefChem:164997, (+-)-Nefopam hydrochloride, CHEBI:88312, 245-585-5, 5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-benzo[f][1,4]oxazocine hydrochloride, Fenazoxine hydrochloride, Nefopam (hydrochloride), 1H-2,5-Benzoxazocine, 3,4,5,6-tetrahydro-5-methyl-1-phenyl-, hydrochloride (1:1), Nefopam hydrochloride [USAN], 5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine hydrochloride, MFCD00012750, 5-methyl-1-phenyl-1,3,4,6-tetrahydro-2,5-benzoxazocine, hydrochloride, Nefopam hydrochloride (USAN), Leoplexamin, Pallopikeron, Lenipan, Sinalgico, Oxadol, Ajan, 5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocin-5-ium, chloride, SMR000514529, SR-01000388442, 5-methyl-1-phenyl-1H,3H,4H,6H-benzo[f]1,4-oxazocine, chloride, 69319-31-9, UNII-685J48E13W, Prestwick_351, EINECS 245-585-5, Nefopan hydrochloride, Acupan (TN), 23327-57-3 (HCl), NCGC00016778-01, R 738, 5-methyl-1-phenyl-1,3,4,6-tetrahydro-2,5-benzoxazocine hydrochloride, CAS-23327-57-3, MLS001210851, MLS001240198, MLS002222204, (+/-)-Nefopam hydrochloride, SCHEMBL122057, orb1310581, CHEMBL1407915, SCHEMBL29390434, MSK10266A, Nefopam HCl - Bio-X trade mark, 5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine--hydrogen chloride (1/1), CNNVSINJDJNHQK-UHFFFAOYSA-N, GLXC-08157, HMS1568N19, NEFOPAM HYDROCHLORIDE [MI], HY-B1057, Tox21_110606, EBC-75122, s4180, SBB057307, NEFOPAM HYDROCHLORIDE [MART.], 5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-benzo[f][1,4]oxazocinehydrochloride, AKOS015845828, NEFOPAM HYDROCHLORIDE [WHO-DD], Tox21_110606_1, CCG-220229, CS-4579, FN26174, FN65100, NSC 757856, Nefopam hydrochloride, >=98% (HPLC), NCGC00094906-06, AC-11999, AS-13286, SY102029, CAS#23327-57-3, DB-046129, N1169, NS00084481, ST50319951, C74201, D05133, F241971, SR-01000388442-1, SR-01000388442-4, Q27264216, Nefopam Hydrochloride 1.0 mg/ml in Methanol (as free base), 5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-benzo[f][1,4]oxazocine HCl, 1H-2,5-BENZOXAZOCINE, 5-METHYL-1-PHENYL-3,4,5,6-TETRAHYDRO-, HYDROCHLORIDE

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
1-Butanol	273.15	-	0.6613	[304]
1-Butanol	278.15	-	0.7867	[304]
1-Butanol	283.15	-	0.9173	[304]
1-Butanol	288.15	-	1.174	[304]
1-Butanol	293.15	-	1.466	[304]
1-Butanol	298.15	-	1.907	[304]
1-Butanol	303.15	-	2.435	[304]
1-Butanol	308.15	-	3.08	[304]
1-Butanol	313.15	-	3.887	[304]
1-Butanol	318.15	-	4.923	[304]
1-Butanol	323.15	-	6.103	[304]
1-Propanol	273.15	-	1.151	[304]
1-Propanol	278.15	-	1.291	[304]
1-Propanol	283.15	-	1.516	[304]
1-Propanol	288.15	-	1.928	[304]
1-Propanol	293.15	-	2.528	[304]
1-Propanol	298.15	-	3.226	[304]
1-Propanol	303.15	-	4.071	[304]
1-Propanol	308.15	-	5.122	[304]
1-Propanol	313.15	-	6.47	[304]
1-Propanol	318.15	-	8.063	[304]
1-Propanol	323.15	-	10.06	[304]
Acetone	273.15	-	0.292	[304]
Acetone	278.15	-	0.351	[304]
Acetone	283.15	-	0.4282	[304]
Acetone	288.15	-	0.5087	[304]
Acetone	293.15	-	0.5954	[304]
Acetone	298.15	-	0.7129	[304]
Acetone	303.15	-	0.8359	[304]
Acetone	308.15	-	1.023	[304]
Acetone	313.15	-	1.195	[304]
Acetone	318.15	-	1.418	[304]
Acetone	323.15	-	1.679	[304]
Ethanol	273.15	-	6.913	[304]
Ethanol	278.15	-	8.243	[304]
Ethanol	283.15	-	9.954	[304]
Ethanol	288.15	-	12.36	[304]
Ethanol	293.15	-	14.4	[304]
Ethanol	298.15	-	16.71	[304]
Ethanol	303.15	-	19.83	[304]
Ethanol	308.15	-	23.21	[304]
Ethanol	313.15	-	27.31	[304]
Ethanol	318.15	-	31.79	[304]
Ethanol	323.15	-	38.47	[304]
Isobutanol	273.15	-	1.327	[304]
Isobutanol	278.15	-	1.668	[304]
Isobutanol	283.15	-	2.012	[304]
Isobutanol	288.15	-	2.513	[304]
Isobutanol	293.15	-	2.997	[304]
Isobutanol	298.15	-	3.623	[304]
Isobutanol	303.15	-	4.478	[304]
Isobutanol	308.15	-	5.417	[304]
Isobutanol	313.15	-	6.593	[304]
Isobutanol	318.15	-	7.97	[304]
Isobutanol	323.15	-	9.797	[304]
Isopropanol	273.15	-	0.5267	[304]
Isopropanol	278.15	-	0.6433	[304]
Isopropanol	283.15	-	0.7892	[304]
Isopropanol	288.15	-	0.9564	[304]
Isopropanol	293.15	-	1.21	[304]
Isopropanol	298.15	-	1.534	[304]
Isopropanol	303.15	-	1.852	[304]
Isopropanol	308.15	-	2.267	[304]
Isopropanol	313.15	-	2.788	[304]
Isopropanol	318.15	-	3.447	[304]
Isopropanol	323.15	-	4.179	[304]
Methanol	273.15	-	37.92	[304]
Methanol	278.15	-	41.45	[304]
Methanol	283.15	-	46.04	[304]
Methanol	288.15	-	50.15	[304]
Methanol	293.15	-	55.08	[304]
Methanol	298.15	-	61.4	[304]
Methanol	303.15	-	67.88	[304]
Methanol	308.15	-	74.85	[304]
Methanol	313.15	-	81.61	[304]
Methanol	318.15	-	90.06	[304]
Methanol	323.15	-	100.4	[304]
Water	273.15	-	15.42	[304]
Water	278.15	-	17.07	[304]
Water	283.15	-	19.97	[304]
Water	288.15	-	23.18	[304]
Water	293.15	-	26.86	[304]
Water	298.15	-	31.98	[304]
Water	303.15	-	37.57	[304]
Water	308.15	-	43.77	[304]
Water	313.15	-	50.76	[304]
Water	318.15	-	59.0	[304]
Water	323.15	-	68.0	[304]

Molecule 3D descriptors

Descriptor	Value
PMI1	859.8842
PMI2	1768.5287
PMI3	2346.5485
NPR1	0.3664
NPR2	0.7537
RadiusOfGyration	2.9297
InertialShapeFactor	0.0009
Eccentricity	0.9304
Asphericity	0.2723
SpherocityIndex	0.2508
PBF	0.7907