Rosiglitazone

Molecular Mass: 357.4 g/mol

Formula: C₁₈H₁₉N₃O₃S

Smiles: CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)c1ccccn1

Synonymes:

Rosiglitazone, rosiglitazone, 122320-73-4, Rosiglizole, Brl-49653, Rezult, rosiglitazona, Gaudil, Rosvel, BRL49653, rosiglitazonum, NSC-758698, 2,4-thiazolidinedione, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione, 05V02F2KDG, TDZ-01, DTXSID7037131, CHEBI:50122, 2,4-Thiazolidinedione, 5-((4-(2-(methyl-2-pyridinylamino)ethoxy)phenyl)methyl)-, 5-((4-(2-Methyl-2-(pyridinylamino)ethoxy)phenyl)methyl)-2,4-thiazolidinedione-2-butenedioate, DTXCID5017131, 5-((4-(2-(methyl-2-pyridinylamino)ethoxy)phenyl)methyl)-2,4-thiazolidinedione, 5-((4-(2-(methyl-pyridin-2-ylamino)ethoxy)phenyl)methyl)-1,3-thiazolidine-2,4-dione, 5-[[4-[2-(methyl-pyridin-2-ylamino)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione, RefChem:56529, A10BG02, 5-(4-(2-(Methyl(pyridin-2-yl)amino)ethoxy)benzyl)thiazolidine-2,4-dione, Avandia, Brl 49653, Avandamet, Avandaryl, TDZ 01, Rosiglitazone base, MFCD00871760, 5-[4-[2-(N-Methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione, 5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione, Rosiglitazone (INN), NCGC00095124-01, S2556, ROSIGLITAZONE [INN], 5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)methyl]-1,3-thiazolidine-2,4-dione, rosiglitazone (Avandia), Rosiglitazone [INN:BAN], 5-(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}benzyl)-1,3-thiazolidine-2,4-dione, CAS-122320-73-4, SR-01000763023, UNII-05V02F2KDG, Rosigltazone, HSDB 7555, 5-[4-[2-[N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione, Gaudil (TN), Spectrum_001703, Rosiglitazone (Standard), 1217260-35-9, Spectrum2_001241, Spectrum3_000997, Spectrum4_001125, Spectrum5_001464, ROSIGLITAZONE [MI], SCHEMBL5169, ROSIGLITAZONE [HSDB], ROSIGLITAZONE [IARC], BSPBio_002693, KBioGR_001609, KBioSS_002183, ROSIGLITAZONE [VANDF], ROSIGLITAZONE [MART.], SPECTRUM1504263, SPBio_001142, ROSIGLITAZONE [WHO-DD], GTPL1056, orb1310711, ROSIGLITAZONE [EMA EPAR], SCHEMBL14383595, SCHEMBL14383596, SCHEMBL29530259, KBio2_002183, KBio2_004751, KBio2_007319, KBio3_001913, Rosiglitazone - Bio-X trade mark, Rosiglitazone, >=98% (HPLC), BDBM723998, GLXC-06376, HMS1922J11, HMS2094O13, HMS3649G08, HMS3656K16, HMS3744M11, HMS3871L03, HMS3884N08, HMS5081F03, Pharmakon1600-01504263, MSK11057, Tox21_111434, 5-[4-[2-[Methyl(2-pyridyl)amino]ethoxy]benzyl]thiazolidine-2,4-dione, BDBM50030474, CCG-39102, EBC-14154, HB2556, HY-17386R, NSC758698, STL350047, 5-[[4-[2-[methyl(2-pyridyl)amino]ethoxy]phenyl]methyl]thiazolidine-2,4-dione, AKOS015894872, O-De-Me, 2-O-B-D-galactopyranoside, Tox21_111434_1, AC-3459, DB00412, FR39350, NSC 758698, SB17326, NCGC00095124-02, NCGC00095124-03, NCGC00095124-04, NCGC00095124-05, NCGC00095124-06, NCGC00095124-08, BR164372, HY-17386, SY031184, US20250064791, Compound Rosiglitazone, NS00008920, R0106, SW197573-6, 6P-065, D08491, S00306, AB00698473-15, AB00698473-17, AB00698473-18, AB00698473-19, AB00698473_20, AB00698473_21, AB00698473_22, AB00698473_23, F093413, Q424771, SR-01000763023-5, SR-01000763023-6, BRD-A97437073-001-02-3, BRD-A97437073-001-03-1, BRD-A97437073-001-04-9, BRD-A97437073-001-08-0, BRD-A97437073-003-14-4, BRD-A97437073-050-13-7, BRD-A97437073-050-14-5, SR-01000763023-12, (RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion, 5-(4-(2-(Methyl(pyridin-2-yl)amino)ethoxy)-benzyl)thiazolidine-2,4-dione, 5-[4-[2-(N-Methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4dione, (+/-)-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione, 2,4-Thiazolidinedione, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]- (9CI), 5-(4-(2-(N-METHYL-N-(2-PYRIDINYL)AMINO)ETHOXY)BENZYL)-2,4-THIAZOLIDINEDIONE, 5-[[4-[2-(methyl-(2-pyridyl)amino)ethoxy]phenyl]methyl] thiazolidine-2,4-dione, 5-[[4-[2-(methyl-2-pyridinylamino) ethoxy]phenyl]methyl]-2,4-thiazolidinedione, 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl] thiazolidine-2,4-dione, 5-[4-[2-[N-methyl-N-(2-pyridyl)amino]ethoxy]phenyl methyl]thiazolidine-2,4-dione, BRL 49653, BRL49653, BRL-49653, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
1-Butanol	283.15	-	1.346	[307]
1-Butanol	293.15	-	1.451	[307]
1-Butanol	303.15	-	1.62	[307]
1-Butanol	313.15	-	2.415	[307]
1-Butanol	323.15	-	5.568	[307]
1-Butanol	333.15	-	11.06	[307]
1-Propanol	283.15	-	1.333	[307]
1-Propanol	293.15	-	1.339	[307]
1-Propanol	303.15	-	1.528	[307]
1-Propanol	313.15	-	3.471	[307]
1-Propanol	323.15	-	6.176	[307]
1-Propanol	333.15	-	13.35	[307]
Acetone	283.15	-	8.772	[307]
Acetone	293.15	-	13.57	[307]
Acetone	303.15	-	21.92	[307]
Acetone	313.15	-	32.87	[307]
Acetone	323.15	-	46.62	[307]
Acetonitrile	283.15	-	1.847	[307]
Acetonitrile	293.15	-	3.089	[307]
Acetonitrile	303.15	-	5.0	[307]
Acetonitrile	313.15	-	8.361	[307]
Acetonitrile	323.15	-	10.87	[307]
Acetonitrile	333.15	-	22.73	[307]
Butyl acetate	283.15	-	2.539	[307]
Butyl acetate	293.15	-	3.169	[307]
Butyl acetate	303.15	-	6.312	[307]
Butyl acetate	313.15	-	9.445	[307]
Butyl acetate	323.15	-	13.32	[307]
Butyl acetate	333.15	-	24.08	[307]
Ethanol	283.15	-	1.516	[307]
Ethanol	293.15	-	2.089	[307]
Ethanol	303.15	-	2.775	[307]
Ethanol	313.15	-	4.02	[307]
Ethanol	323.15	-	7.339	[307]
Ethanol	333.15	-	14.33	[307]
Ethyl acetate	283.15	-	4.555	[307]
Ethyl acetate	293.15	-	7.502	[307]
Ethyl acetate	303.15	-	10.83	[307]
Ethyl acetate	313.15	-	15.73	[307]
Ethyl acetate	323.15	-	22.87	[307]
Ethyl acetate	333.15	-	41.17	[307]
Isopropanol	283.15	-	0.6161	[307]
Isopropanol	293.15	-	0.8089	[307]
Isopropanol	303.15	-	1.306	[307]
Isopropanol	313.15	-	2.417	[307]
Isopropanol	323.15	-	4.486	[307]
Isopropanol	333.15	-	9.752	[307]
Methanol	283.15	-	1.237	[307]
Methanol	293.15	-	1.618	[307]
Methanol	303.15	-	3.872	[307]
Methanol	313.15	-	6.423	[307]
Methanol	323.15	-	11.25	[307]
Methanol	333.15	-	19.83	[307]
Methyl acetate	283.15	-	5.609	[307]
Methyl acetate	293.15	-	9.251	[307]
Methyl acetate	303.15	-	14.95	[307]
Methyl acetate	313.15	-	22.91	[307]
Methyl acetate	323.15	-	34.59	[307]
Methyl acetate	333.15	-	54.26	[307]

Molecule 3D descriptors

Descriptor	Value
PMI1	1167.1906
PMI2	8219.6274
PMI3	8514.3419
NPR1	0.1371
NPR2	0.9654
RadiusOfGyration	5.0041
InertialShapeFactor	0.0008
Eccentricity	0.9906
Asphericity	0.6479
SpherocityIndex	0.1857
PBF	1.0365