Cilostazol

CAS Number: 73963-72-1

Molecular Mass: 369.5 g/mol

Formula: C₂₀H₂₇N₅O₂

Smiles: O=C1CCc2cc(OCCCCc3nnnn3C3CCCCC3)ccc2N1

Synonymes:

Cilostazol, cilostazol, 73963-72-1, Pletal, Cilostazole, Pletaal, OPC-13013, Cilostazolum, OPC-21, 6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone, 3,4-Dihydro-6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-2(1H)-quinolinone, 6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydro-2(1H)-quinolinone, NSC-758936, DTXSID9045132, CHEBI:31401, 6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydrocarbostyril, N7Z035406B, DTXCID7025132, 2(1H)-Quionlinone, 6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydro-, 6-[4-(1-cyclohexyl-1h-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril, 2(1H)-quinolinone, 6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydro-, 6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)-butoxy)-3,4-dihydro-1H-quinolin-2-one, 6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)-butoxy]-3,4-dihydro-1H-quinolin-2-one, RefChem:58562, 6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butyloxy)-3,4-dihydroquinolin-2(1H)-one, Cilostazolum [INN-Latin], 6-[4-(1-cyclohexyltetrazol-5-yl)butoxy]-3,4-dihydro-1H-quinolin-2-one, 6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydroquinolin-2(1H)-one, C20H27N5O2, MFCD00866780, 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydroquinolin-2(1H)-one, MLS000028470, 6-[4-(1-cyclohexyl-1H-1,2,3,4-tetrazol-5-yl)butoxy]-1,2,3,4-tetrahydroquinolin-2-one, NCGC00015207-07, SMR000058428, 6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)-butoxy]-3,4-dihydro-2(1H)-quinolinone, OPC 21, CAS-73963-72-1, Pletal (TN), SR-01000003107, BRN 3632107, UNII-N7Z035406B, Cilostazol [USAN:USP:INN:BAN:JAN], Cilostazol (Standard), Tocris-1692, CILOSTAZOL [MI], Opera_ID_488, CILOSTAZOL [INN], CILOSTAZOL [JAN], Spectrum2_001118, Spectrum3_001170, Spectrum4_000772, Spectrum5_001762, CILOSTAZOL [USAN], Lopac-C-0737, CILOSTAZOL [VANDF], CHEMBL799, C 0737, CILOSTAZOL [MART.], CILOSTAZOL [USP-RS], CILOSTAZOL [WHO-DD], Lopac0_000218, REGID_for_CID_2754, SCHEMBL16128, BSPBio_002759, KBioGR_001184, MLS000758281, MLS000759507, MLS001076067, MLS002153891, SPECTRUM1505230, SPBio_001256, Cilostazol (JP18/USP/INN), GTPL7148, orb1310589, orb3141224, CILOSTAZOL [ORANGE BOOK], SCHEMBL27771101, SCHEMBL29389547, HSDB 8312, KBio3_002259, CILOSTAZOL [USP MONOGRAPH], HMS1922N15, HMS2093M14, HMS2096F16, HMS2234C06, HMS3260L17, HMS3268O09, HMS3412B18, HMS3654J13, HMS3676B18, HMS3713F16, HMS5079N07, Pharmakon1600-01505230, Tox21_110098, Tox21_500218, BDBM50225508, CCG-39646, EBC-11191, HY-17464R, MSK160188, NSC758936, s1294, AKOS015855512, Cilostazol, >=98% (HPLC), powder, OPC 13013, OPC 21, Pletaal, Tox21_110098_1, AC-4334, CS-1759, DB01166, FC03161, KS-5154, LP00218, NSC 758936, SDCCGSBI-0050206.P003, 2(1H)-Quinolinone, 3,4-dihydro-6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-, NCGC00015207-01, NCGC00015207-02, NCGC00015207-03, NCGC00015207-04, NCGC00015207-05, NCGC00015207-06, NCGC00015207-08, NCGC00015207-09, NCGC00015207-10, NCGC00015207-11, NCGC00015207-12, NCGC00015207-25, NCGC00022153-02, NCGC00022153-04, NCGC00022153-05, NCGC00022153-06, NCGC00022153-07, NCGC00260903-01, HY-17464, SBI-0050206.P002, C2587, EU-0100218, NS00009762, SW199053-2, T0462, D01896, F20538, AB00382988-14, AB00382988_15, AB00382988_16, F862750, Q258591, SR-01000003107-2, SR-01000003107-4, SR-01000003107-7, BRD-K67017579-001-04-2, BRD-K67017579-001-05-9, BRD-K67017579-001-07-5, BRD-K67017579-001-13-3, BRD-K67017579-001-17-4, BRD-K67017579-001-26-5, BRD-K67017579-001-27-3, BRD-K67017579-001-28-1, SR-01000003107-10, Z1501485368, Cilostazol, United States Pharmacopeia (USP) Reference Standard, 6-[4-(1-cyclohexyl-1,2,3,4-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril, 6-[4-(l-cyclohexyl-1,2,3,4-tetrazol-5-yl)butoxyl]-3,4-dihydrocarbostyril, Cilostazol, Pharmaceutical Secondary Standard, Certified Reference Material, 6-(4-(1-CYCLOHEXYL-1H-TETRAZOL-5-YL)BUTOXY)QUINOLINE-2,3(1H,4H)-DIONE, 6-[4-(1-Cyclohexyl-5-tetrazolyl)butoxy]-1,2,3,4- tetrahydro-2-oxoquinolinone

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
1,4-Dioxane	288.15	-	23.03	[331]
1,4-Dioxane	293.15	-	26.63	[331]
1,4-Dioxane	298.15	-	30.76	[331]
1,4-Dioxane	303.15	-	35.41	[331]
1,4-Dioxane	308.15	-	40.9	[331]
1,4-Dioxane	313.15	-	47.82	[331]
1-Butanol	273.15	-	1.798	[331]
1-Butanol	278.15	-	2.687	[331]
1-Butanol	283.15	-	3.699	[331]
1-Butanol	288.15	-	4.835	[331]
1-Butanol	293.15	-	6.071	[331]
1-Butanol	298.15	-	7.389	[331]
1-Butanol	303.15	-	8.916	[331]
1-Butanol	308.15	-	10.48	[331]
1-Butanol	313.15	-	12.21	[331]
1-Propanol	273.15	-	1.039	[331]
1-Propanol	278.15	-	1.676	[331]
1-Propanol	283.15	-	2.432	[331]
1-Propanol	288.15	-	3.15	[331]
1-Propanol	293.15	-	4.02	[331]
1-Propanol	298.15	-	4.82	[331]
1-Propanol	303.15	-	5.672	[331]
1-Propanol	308.15	-	6.647	[331]
1-Propanol	313.15	-	7.735	[331]
Acetone	273.15	-	8.704	[331]
Acetone	278.15	-	10.62	[331]
Acetone	283.15	-	12.49	[331]
Acetone	288.15	-	14.59	[331]
Acetone	293.15	-	16.73	[331]
Acetone	298.15	-	19.1	[331]
Acetone	303.15	-	21.53	[331]
Acetone	308.15	-	24.09	[331]
Acetone	313.15	-	27.37	[331]
Acetonitrile	273.15	-	2.2	[331]
Acetonitrile	278.15	-	3.64	[331]
Acetonitrile	283.15	-	5.038	[331]
Acetonitrile	288.15	-	6.636	[331]
Acetonitrile	293.15	-	8.382	[331]
Acetonitrile	298.15	-	10.6	[331]
Acetonitrile	303.15	-	12.98	[331]
Acetonitrile	308.15	-	15.58	[331]
Acetonitrile	313.15	-	18.73	[331]
Ethanol	273.15	-	1.088	[331]
Ethanol	278.15	-	1.816	[331]
Ethanol	283.15	-	2.598	[331]
Ethanol	288.15	-	3.44	[331]
Ethanol	293.15	-	4.37	[331]
Ethanol	298.15	-	5.34	[331]
Ethanol	303.15	-	6.383	[331]
Ethanol	308.15	-	7.631	[331]
Ethanol	313.15	-	8.95	[331]
Ethyl acetate	273.15	-	0.4463	[331]
Ethyl acetate	278.15	-	0.7898	[331]
Ethyl acetate	283.15	-	1.19	[331]
Ethyl acetate	288.15	-	1.628	[331]
Ethyl acetate	293.15	-	2.101	[331]
Ethyl acetate	298.15	-	2.643	[331]
Ethyl acetate	303.15	-	3.21	[331]
Ethyl acetate	308.15	-	3.778	[331]
Ethyl acetate	313.15	-	4.358	[331]
Isopropanol	273.15	-	0.415	[331]
Isopropanol	278.15	-	0.7613	[331]
Isopropanol	283.15	-	1.138	[331]
Isopropanol	288.15	-	1.574	[331]
Isopropanol	293.15	-	2.034	[331]
Isopropanol	298.15	-	2.609	[331]
Isopropanol	303.15	-	3.265	[331]
Isopropanol	308.15	-	3.961	[331]
Isopropanol	313.15	-	4.638	[331]
Methanol	273.15	-	2.41	[331]
Methanol	278.15	-	3.81	[331]
Methanol	283.15	-	5.292	[331]
Methanol	288.15	-	6.924	[331]
Methanol	293.15	-	8.72	[331]
Methanol	298.15	-	10.6	[331]
Methanol	303.15	-	12.7	[331]
Methanol	308.15	-	14.9	[331]
Methanol	313.15	-	17.19	[331]
Methyl ethyl ketone	273.15	-	12.26	[331]
Methyl ethyl ketone	278.15	-	14.54	[331]
Methyl ethyl ketone	283.15	-	16.75	[331]
Methyl ethyl ketone	288.15	-	19.36	[331]
Methyl ethyl ketone	293.15	-	21.96	[331]
Methyl ethyl ketone	298.15	-	24.72	[331]
Methyl ethyl ketone	303.15	-	27.76	[331]
Methyl ethyl ketone	308.15	-	31.54	[331]
Methyl ethyl ketone	313.15	-	35.69	[331]

Molecule 3D descriptors

Descriptor	Value
PMI1	1007.9775
PMI2	9309.4809
PMI3	9587.9169
NPR1	0.1051
NPR2	0.9710
RadiusOfGyration	5.1902
InertialShapeFactor	0.0010
Eccentricity	0.9945
Asphericity	0.7198
SpherocityIndex	0.1527
PBF	1.0373