Ribavirin(II)

CAS Number: 36791-04-5

Molecular Mass: 244.2 g/mol

Formula: C₈H₁₂N₄O₅

Smiles: NC(=O)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)n1

Synonymes:

Ribavirin(II), ribavirin, 36791-04-5, Tribavirin, Rebetol, Virazole, Copegus, Vilona, Ribamidil, Ribasphere, Ribavirine, Viramid, RTCA, Ribavirina, Varazid, Ribavirinum, Cotronak, 1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide, ICN-1229, Virazid, Ribavirin Mylan, Ribavirin Teva, 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide, Ribavirin BioPartners, SCH 18908, DTXSID8023557, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide, Ribavirin Teva Pharma B.V., NSC-163039, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide, CHEBI:63580, 49717AWG6K, ribofluranosyl carboxamide, 1H-1,2,4-Triazole-3-carboxamide, 1-beta-D-ribofuranosyl-, SCH-18908, DTXCID603557, Ribovirin, Viramide, NSC 163039, NSC163039, Ribavarin, ICN 1229, Ribapak, ICN1229, 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-1,2,4-triazole-3-carboxamide, 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-1H-1,2,4-triazole-3-carboxamide, RefChem:6200, J05AP01, 1-Beta-D-ribofuranosyl-1,2,4-triazolo-3-carboxamide, 1-beta-d-ribofuranosyl-1h-1,2, 4-triazole-3-carboxamide, 636-825-3, Ribamide, Ribavirine [INN-French], Ribavirinum [INN-Latin], Ribavirina [INN-Spanish], MFCD00058564, 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-1,2,4-triazole-3-carboxamide, RBV, Ribamidyl, Rebetron, Ribavirin Capsules, 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide, Rebretron, Virazide, 1H-1,2,4-Triazole-3-carboxamide, 1-.beta.-D-ribofuranosyl-, Ribav, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,2,4-triazole-3-carboxamide, 1-ss-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide, RTC, Ravanex, Ribacine, C-Virin, DRG-0028, Ribasphere (TN), Virazole (TN), SMR000058315, Copegus (TN), Rebetol (TN), HSDB 6513, SR-01000076112, BRN 0892462, Ribavirvin, UNII-49717AWG6K, VirustazCotronak, Tribavirin, , Ribamidil, , Virazide, , Virazole, , s2504, Viramid, , Viratek, , Virazid, , Ribavirin CRS, Vilona, , Ribavirin [USAN:USP:INN:BAN], NCGC00015904-02, 66510-90-5, Ribavirin, antiviral, CAS-36791-04-5, RG-964, Ribavirin (Copegus), Ribavirin (Standard), Ribavirin (Copegus)?, Ro-20-9963, Spectrum_001826, 4pb1, RIBAVIRIN [INN], RIBAVIRIN [JAN], RIBAVIRIN [MI], RIBAVIRIN [HSDB], RIBAVIRIN [USAN], Prestwick3_000993, Spectrum3_001876, Spectrum4_001252, Spectrum5_002075, RIBAVIRIN [VANDF], R-964, Epitope ID:768752, RIBAVIRIN [MART.], R 9644, RIBAVIRIN [USP-RS], RIBAVIRIN [WHO-DD], SCHEMBL3727, 1-.beta.-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide, CHEMBL1643, Lopac0_001063, BSPBio_001085, BSPBio_003352, KBioGR_001804, KBioSS_002331, RIBAVIRIN [EMA EPAR], AA-504/07617051, cid_37542, MLS000028486, MLS002222317, DivK1c_000782, SPECTRUM1503938, Ribavirin (JP18/USP/INN), BPBio1_001195, GTPL6842, orb1310388, orb3140076, RIBAVIRIN [ORANGE BOOK], 1,2,4-Triazole-3-carboxamide, 1-beta-D-ribofuranosyl-, 1-.beta.-D-Ribofuranosyl-1,2,4-triazolo-3-carboxamide, RIBAVIRIN [EP MONOGRAPH], HMS502H04, HY-B0434R, KBio1_000782, KBio2_002328, KBio2_004896, KBio2_007464, KBio3_002854, RIBAVIRIN [USP MONOGRAPH], NINDS_000782, GLXC-05861, HMS2090L15, HMS2094O09, HMS2098G07, HMS2232P07, HMS3263E08, HMS3715G07, Pharmakon1600-01503938, ALBB-038667, HY-B0434, MSK10023, Tox21_110259, Tox21_200967, Tox21_501063, BDBM50154375, CCG-38985, EBC-00633, HB4522, NSC758650, AKOS001715163, Tox21_110259_1, DB00811, GS-3572, LP01063, NR02712, NSC-758650, SDCCGSBI-0051033.P004, IDI1_000782, SMP1_000261, NCGC00090726-01, NCGC00090726-03, NCGC00090726-04, NCGC00090726-05, NCGC00090726-06, NCGC00090726-07, NCGC00090726-08, NCGC00090726-09, NCGC00090726-12, NCGC00090726-25, NCGC00090726-30, NCGC00258520-01, NCGC00261748-01, 252269-50-4, AS-34178, SY055294, SBI-0051033.P003, AB00430481, EU-0101063, NS00009126, R0077, EN300-59237, D00423, AB00430481-15, AB00430481-16, AB00430481_17, AB00430481_18, Ribavirin, Antibiotic for Culture Media Use Only, 1-beta-Ribofuranosyl-1,2,4-triazole-3-carboamide, F079125, Q421862, Ribavirin 100 microg/mL in Acetonitrile:Methanol, SR-01000721904, 1-b-d-ribofuranosyl-1,2,4-triazole-3-carboxamide, Q-201670, SR-01000076112-2, SR-01000076112-3, SR-01000076112-4, SR-01000721904-2, BRD-K60369935-001-02-7, BRD-K60369935-001-15-9, BRD-K60369935-001-18-3, SR-01000076112-11, 1-(beta-D-Ribofuranosyl)-1,2,4-triazole-3-carboxamide, 1-|_-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide, 1-|A-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide, Ribavirin, British Pharmacopoeia (BP) Reference Standard, Z594284196, 1-(beta -D-ribofuranosyl)-1,2,4-triazole-3-carboxamide, Ribavirin, European Pharmacopoeia (EP) Reference Standard, Ribavirin, United States Pharmacopeia (USP) Reference Standard, Ribavirin, Pharmaceutical Secondary Standard, Certified Reference Material, 1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide, 1-?-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
1,4-Dioxane	283.15	-	0.2048	[333]
1,4-Dioxane	288.15	-	0.2909	[333]
1,4-Dioxane	293.15	-	0.4166	[333]
1,4-Dioxane	298.15	-	0.5779	[333]
1,4-Dioxane	303.15	-	0.8003	[333]
1,4-Dioxane	308.15	-	1.091	[333]
1,4-Dioxane	313.15	-	1.478	[333]
1,4-Dioxane	318.15	-	1.986	[333]
1-Butanol	283.15	-	0.2003	[332]
1-Butanol	288.15	-	0.2399	[332]
1-Butanol	293.15	-	0.3126	[332]
1-Butanol	298.15	-	0.3967	[332]
1-Butanol	303.15	-	0.4617	[332]
1-Butanol	308.15	-	0.5521	[332]
1-Butanol	313.15	-	0.6432	[332]
1-Butanol	318.15	-	0.7517	[332]
1-Butanol	323.15	-	0.9389	[332]
1-Propanol	278.15	-	0.1985	[333]
1-Propanol	283.15	-	0.2867	[333]
1-Propanol	283.15	-	0.1508	[332]
1-Propanol	288.15	-	0.4	[333]
1-Propanol	288.15	-	0.188	[332]
1-Propanol	293.15	-	0.5601	[333]
1-Propanol	293.15	-	0.2609	[332]
1-Propanol	298.15	-	0.7855	[333]
1-Propanol	298.15	-	0.3324	[332]
1-Propanol	303.15	-	1.074	[333]
1-Propanol	303.15	-	0.422	[332]
1-Propanol	308.15	-	1.463	[333]
1-Propanol	308.15	-	0.5186	[332]
1-Propanol	313.15	-	1.975	[333]
1-Propanol	313.15	-	0.6222	[332]
1-Propanol	318.15	-	2.64	[333]
1-Propanol	318.15	-	0.7485	[332]
1-Propanol	323.15	-	0.9358	[332]
2-Butanol	283.15	-	0.2109	[332]
2-Butanol	288.15	-	0.2262	[332]
2-Butanol	293.15	-	0.2556	[332]
2-Butanol	298.15	-	0.2754	[332]
2-Butanol	303.15	-	0.32	[332]
2-Butanol	308.15	-	0.3544	[332]
2-Butanol	313.15	-	0.4193	[332]
2-Butanol	318.15	-	0.5059	[332]
2-Butanol	323.15	-	0.5755	[332]
Acetone	283.15	-	0.1271	[332]
Acetone	288.15	-	0.149	[332]
Acetone	293.15	-	0.1804	[332]
Acetone	298.15	-	0.2099	[332]
Acetone	303.15	-	0.2578	[332]
Acetone	308.15	-	0.306	[332]
Acetone	313.15	-	0.3676	[332]
Acetone	318.15	-	0.4434	[332]
Acetone	323.15	-	0.4877	[332]
Acetonitrile	278.15	-	0.0409	[333]
Acetonitrile	283.15	-	0.0628	[333]
Acetonitrile	288.15	-	0.091	[333]
Acetonitrile	293.15	-	0.1289	[333]
Acetonitrile	298.15	-	0.183	[333]
Acetonitrile	303.15	-	0.259	[333]
Acetonitrile	308.15	-	0.3589	[333]
Acetonitrile	313.15	-	0.4963	[333]
Acetonitrile	318.15	-	0.674	[333]
Dimethyl sulfoxide	293.15	-	193.4	[332]
Dimethyl sulfoxide	298.15	-	241.5	[332]
Dimethyl sulfoxide	303.15	-	276.3	[332]
Dimethyl sulfoxide	308.15	-	303.5	[332]
Dimethyl sulfoxide	313.15	-	354.4	[332]
Dimethyl sulfoxide	318.15	-	413.7	[332]
Dimethyl sulfoxide	323.15	-	475.9	[332]
Ethanol	283.15	-	0.2516	[332]
Ethanol	288.15	-	0.3596	[332]
Ethanol	293.15	-	0.491	[332]
Ethanol	298.15	-	0.6558	[332]
Ethanol	303.15	-	0.8641	[332]
Ethanol	308.15	-	1.161	[332]
Ethanol	313.15	-	1.389	[332]
Ethanol	318.15	-	1.771	[332]
Ethanol	323.15	-	2.234	[332]
Formic Acid	283.15	-	331.1	[332]
Formic Acid	288.15	-	365.7	[332]
Formic Acid	293.15	-	445.4	[332]
Formic Acid	298.15	-	548.3	[332]
Formic Acid	303.15	-	642.0	[332]
Formic Acid	308.15	-	736.7	[332]
Formic Acid	313.15	-	812.9	[332]
Formic Acid	318.15	-	949.2	[332]
Formic Acid	323.15	-	1185.1	[332]
Methanol	278.15	-	2.325	[333]
Methanol	283.15	-	3.154	[333]
Methanol	283.15	-	3.514	[332]
Methanol	288.15	-	4.314	[333]
Methanol	288.15	-	4.037	[332]
Methanol	293.15	-	5.746	[333]
Methanol	293.15	-	4.482	[332]
Methanol	298.15	-	7.669	[333]
Methanol	298.15	-	5.189	[332]
Methanol	303.15	-	10.2	[333]
Methanol	303.15	-	6.116	[332]
Methanol	308.15	-	13.24	[333]
Methanol	308.15	-	7.253	[332]
Methanol	313.15	-	17.29	[333]
Methanol	313.15	-	8.125	[332]
Methanol	318.15	-	22.26	[333]
Methanol	318.15	-	9.873	[332]
Methanol	323.15	-	11.31	[332]
Water	278.15	-	79.12	[333]
Water	283.15	-	105.9	[333]
Water	283.15	-	120.1	[332]
Water	288.15	-	142.2	[333]
Water	288.15	-	142.7	[332]
Water	293.15	-	185.7	[333]
Water	293.15	-	168.4	[332]
Water	298.15	-	239.5	[333]
Water	298.15	-	197.8	[332]
Water	303.15	-	302.2	[333]
Water	303.15	-	226.8	[332]
Water	308.15	-	378.5	[333]
Water	308.15	-	260.8	[332]
Water	313.15	-	465.8	[333]
Water	313.15	-	309.4	[332]
Water	318.15	-	567.0	[333]
Water	318.15	-	371.0	[332]
Water	323.15	-	421.7	[332]

Molecule 3D descriptors

Descriptor	Value
PMI1	526.8762
PMI2	1884.6859
PMI3	2191.3570
NPR1	0.2404
NPR2	0.8601
RadiusOfGyration	3.0699
InertialShapeFactor	0.0016
Eccentricity	0.9707
Asphericity	0.4444
SpherocityIndex	0.1866
PBF	0.6751