Bifonazole

CAS Number: 60628-96-8

Molecular Mass: 310.4 g/mol

Formula: C₂₂H₁₈N₂

Smiles: c1ccc(-c2ccc(C(c3ccccc3)n3ccnc3)cc2)cc1

Synonymes:

Bifonazole, bifonazole, 60628-96-8, Mycospor, Trifonazole, Bifonazol, BAY H 4502, Bifonazolum, 1-((4-Biphenylyl)phenylmethyl)-1H-imidazole, 1-(alpha-(4-Biphenylyl)benzyl)imidazole, Bay-h-4502, Bay H-4502, (+-)-1-(p,alpha-Diphenylbenzyl)imidazole, DTXSID9045631, NSC-758954, QYJ305Z91O, D01AC10, DTXCID7025631, 1-((4-biphenylyl)-phenylmethyl)-1H-imidazole, 1H-Imidazole, 1-((1,1'-biphenyl)-4-ylphenylmethyl)-, (+-)-, 1-(phenyl(4-phenylphenyl)methyl)-1H-imidazole, 1-[phenyl(4-phenylphenyl)methyl]-1H-imidazole, bifonazolo, RefChem:568329, CHEBI:31286, 1-((RS)-(Biphenyl-4-yl)(phenyl)methyl)-1H-imidazole, 262-336-6, Amycor, Azolmen, 1-[phenyl-(4-phenylphenyl)methyl]imidazole, Bifonazol [INN-Spanish], Bifonazolum [INN-Latin], 1H-Imidazole, 1-([1,1'-biphenyl]-4-ylphenylmethyl)-, 1-([1,1'-Biphenyl]-4-yl(phenyl)methyl)-1H-imidazole, (+/-)-Bifonazole, 1-(p,alpha-Diphenylbenzyl)imidazole, MFCD00865567, MLS000028576, CHEMBL277535, 1-[biphenyl-4-yl(phenyl)methyl]-1H-imidazole, 1H-Imidazole, 1-((1,1'-biphenyl)-4-ylphenylmethyl)-, (+-)1-([1,1'-Biphenyl]-4-ylphenylmethyl)-1H-imidazole, NCGC00018254-03, SMR000058970, 1-[biphenyl-4-yl(phenyl)methyl]imidazole, 1-(ALPHA,4-DIPHENYLBENZYL)IMIDAZOLE, 1-({[1,1'-biphenyl]-4-yl}(phenyl)methyl)-1H-imidazole, Mycospor (TN), CAS-60628-96-8, SR-01000003136, EINECS 262-336-6, BRN 0618427, 1-[([1,1'-Biphenyl]-4-yl)(phenyl)methyl]-1H-imidazole, UNII-QYJ305Z91O, Mycosporan, Bedriol, Mycosporan, , Bifazole, , Mycospor, , Bifonazole CRS, Bifonazole [USAN:INN:BAN:JAN], Bifonazole (Standard), CPD000058970, BIFONAZOLE [MI], BIFONAZOLE [INN], BIFONAZOLE [JAN], 1-[PHENYL-(4-PHENYLPHENYL)-METHYL]IMIDAZOLE, Opera_ID_1656, Spectrum2_000035, Spectrum3_001970, (.+/-.)-Bifonazole, BIFONAZOLE [USAN], Imidazole, 1-(alpha-(4-biphenylyl)benzyl)-, 1-(Biphenyl-4-yl-phenyl-methyl)-1H-imidazole, BIFONAZOLE [MART.], cid_2378, BIFONAZOLE [WHO-DD], SCHEMBL36803, BSPBio_003570, 5-23-04-00292 (Beilstein Handbook Reference), MLS000759537, MLS001074074, MLS001424050, SPECTRUM1505309, SPBio_000129, Bifonazole - Bio-X trade mark, orb1309472, orb3139347, Bifonazole (JP18/USAN/INN), BIFONAZOLE [EP IMPURITY], Bifonazole, >=98% (HPLC), CHEBI:78692, HY-B0301R, KBio3_002922, 1-(p,?-Diphenylbenzyl)imidazole, BIFONAZOLE [EP MONOGRAPH], GLXC-01551, HMS1922B18, HMS2051F04, HMS2090K13, HMS2093B09, HMS2232J24, HMS3374H02, HMS3393F04, HMS3651G21, HMS3715L21, HMS5080M15, Pharmakon1600-01505309, HY-B0301, MSK10152, Tox21_110850, BDBM50128548, CCG-39996, DL-338, EBC-01060, NSC758954, s1854, STK618771, Bifonazole for system suitability CRS, AKOS005553008, Tox21_110850_1, AB07497, CCG-100993, DB04794, FP36903, KS-5111, NC00243, NSC 758954, [phenyl(4-phenylphenyl)methyl]imidazole, MRF-0000274, NCGC00018254-02, NCGC00018254-04, NCGC00018254-05, NCGC00018254-08, NCGC00018254-09, NCGC00089815-02, NCGC00089815-03, NCGC00089815-04, AC-15414, BP164253, DA-51112, SY052768, SBI-0206755.P001, 1-(.alpha.-(4-Biphenylyl)benzyl)imidazole, 1-[alpha-(4-biphenylyl)-benzyl]-imidazole, (Biphenyl-4-yl)-imidazol-1-yl-phenylmethane, B4173, NS00003619, ST50993921, SW197623-3, 1-[4-Biphenylyl(phenyl)methyl]-1H-imidazole, VU0239694-7, D01775, EN300-295624, Imidazole, 1-(.alpha.-(4-biphenylyl)benzyl)-, AB00383029-16, AB00383029_17, AB00383029_18, (.+/-.)-1-(p,.alpha.-Diphenylbenzyl)imidazole, F806741, Q421162, 1-(1-Biphenyl-4-yl-2-phenyl-methyl)-1H-imidazole, SR-01000003136-4, SR-01000003136-6, (+/-)-1-(P,.ALPHA.-DIPHENYLBENZYL)IMIDAZOLE, BRD-A94543220-001-02-3, BRD-A94543220-001-12-2, BRD-A94543220-001-23-9, BRD-A94543220-001-24-7, Z275375166, 1-(Biphenyl-4-yl-phenyl-methyl)-1H-imidazole (bifonazole), 1-(Biphenyl-4-yl-phenyl-methyl)-1H-imidazole( Bifanozole), 1-(Biphenyl-4-yl-phenyl-methyl)-1H-imidazole(Bifonazole), 1-[[1,1'-Biphenyl]-4-yl(phenyl)methyl]-1H-imidazole #, Bifonazole, European Pharmacopoeia (EP) Reference Standard, 1H-Imidazole, 1-([1,1'-biphenyl]-4-ylphenylmethyl)-, (.+/-.)-, 1H-IMIDAZOLE, 1-((1,1'-BIPHENYL)-4-YLPHENYLMETHYL)-, (+/-)-, Bifonazole, Pharmaceutical Secondary Standard, Certified Reference Material, Bifonazole for system suitability, European Pharmacopoeia (EP) Reference Standard

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
1-Butanol	283.15	-	13.27	[347]
1-Butanol	288.19	-	17.42	[347]
1-Butanol	293.16	-	22.0	[347]
1-Butanol	298.14	-	27.49	[347]
1-Butanol	303.15	-	34.05	[347]
1-Butanol	308.23	-	44.88	[347]
1-Butanol	313.11	-	55.06	[347]
1-Butanol	318.18	-	68.57	[347]
1-Butanol	323.14	-	86.99	[347]
1-Pentanol	283.1	-	12.93	[347]
1-Pentanol	288.13	-	16.83	[347]
1-Pentanol	293.15	-	21.37	[347]
1-Pentanol	298.19	-	27.12	[347]
1-Pentanol	303.16	-	33.63	[347]
1-Pentanol	308.14	-	42.82	[347]
1-Pentanol	313.17	-	52.7	[347]
1-Pentanol	318.16	-	67.22	[347]
1-Pentanol	323.12	-	83.31	[347]
1-Propanol	278.15	-	5.976	[348]
1-Propanol	283.12	-	16.03	[347]
1-Propanol	283.15	-	8.214	[348]
1-Propanol	288.14	-	19.2	[347]
1-Propanol	288.15	-	11.13	[348]
1-Propanol	293.15	-	24.41	[347]
1-Propanol	293.15	-	14.8	[348]
1-Propanol	298.15	-	19.43	[348]
1-Propanol	298.18	-	29.9	[347]
1-Propanol	303.15	-	25.32	[348]
1-Propanol	303.16	-	37.69	[347]
1-Propanol	308.15	-	32.92	[348]
1-Propanol	308.21	-	47.35	[347]
1-Propanol	313.15	-	43.49	[348]
1-Propanol	313.16	-	59.03	[347]
1-Propanol	318.15	-	54.78	[348]
1-Propanol	318.19	-	70.68	[347]
1-Propanol	323.17	-	86.54	[347]
2-Butanol	283.13	-	7.243	[347]
2-Butanol	288.16	-	9.753	[347]
2-Butanol	293.14	-	12.56	[347]
2-Butanol	298.17	-	16.97	[347]
2-Butanol	303.15	-	21.76	[347]
2-Butanol	308.12	-	28.18	[347]
2-Butanol	313.19	-	36.61	[347]
2-Butanol	318.16	-	48.44	[347]
2-Butanol	323.15	-	60.8	[347]
Acetonitrile	283.24	-	6.533	[347]
Acetonitrile	288.17	-	8.357	[347]
Acetonitrile	293.15	-	10.42	[347]
Acetonitrile	298.14	-	12.99	[347]
Acetonitrile	303.08	-	16.22	[347]
Acetonitrile	308.13	-	20.16	[347]
Acetonitrile	313.16	-	25.35	[347]
Acetonitrile	318.14	-	31.04	[347]
Acetonitrile	323.11	-	38.92	[347]
Butyl acetate	283.13	-	4.558	[347]
Butyl acetate	288.16	-	5.515	[347]
Butyl acetate	293.14	-	6.734	[347]
Butyl acetate	298.19	-	8.11	[347]
Butyl acetate	303.15	-	10.15	[347]
Butyl acetate	308.18	-	12.26	[347]
Butyl acetate	313.14	-	15.67	[347]
Butyl acetate	318.13	-	19.29	[347]
Butyl acetate	323.15	-	25.01	[347]
Dimethylformamide	283.17	-	61.61	[347]
Dimethylformamide	288.13	-	72.87	[347]
Dimethylformamide	293.15	-	85.69	[347]
Dimethylformamide	298.18	-	100.7	[347]
Dimethylformamide	303.14	-	119.0	[347]
Dimethylformamide	308.09	-	140.2	[347]
Dimethylformamide	313.25	-	165.6	[347]
Dimethylformamide	318.13	-	198.8	[347]
Dimethylformamide	323.18	-	233.9	[347]
Ethanol	283.15	-	15.1	[347]
Ethanol	288.18	-	18.34	[347]
Ethanol	293.13	-	21.75	[347]
Ethanol	298.15	-	27.22	[347]
Ethanol	303.17	-	33.88	[347]
Ethanol	308.14	-	41.2	[347]
Ethanol	313.15	-	50.69	[347]
Ethanol	318.2	-	63.62	[347]
Ethanol	323.14	-	78.67	[347]
Ethyl acetate	283.16	-	7.688	[347]
Ethyl acetate	288.14	-	9.766	[347]
Ethyl acetate	293.17	-	12.28	[347]
Ethyl acetate	298.13	-	14.92	[347]
Ethyl acetate	303.18	-	18.22	[347]
Ethyl acetate	308.12	-	22.66	[347]
Ethyl acetate	313.1	-	27.76	[347]
Ethyl acetate	318.13	-	34.96	[347]
Ethyl acetate	323.1	-	42.76	[347]
Isoamyl Alcohol	283.13	-	11.59	[347]
Isoamyl Alcohol	288.17	-	14.71	[347]
Isoamyl Alcohol	293.07	-	18.69	[347]
Isoamyl Alcohol	298.14	-	23.76	[347]
Isoamyl Alcohol	303.17	-	29.81	[347]
Isoamyl Alcohol	308.13	-	37.96	[347]
Isoamyl Alcohol	313.18	-	48.74	[347]
Isoamyl Alcohol	318.15	-	61.35	[347]
Isoamyl Alcohol	323.24	-	80.1	[347]
Isobutanol	283.14	-	10.49	[347]
Isobutanol	288.17	-	13.89	[347]
Isobutanol	293.13	-	17.82	[347]
Isobutanol	298.12	-	22.18	[347]
Isobutanol	303.16	-	29.01	[347]
Isobutanol	308.15	-	38.25	[347]
Isobutanol	313.19	-	49.32	[347]
Isobutanol	318.14	-	65.69	[347]
Isobutanol	323.16	-	85.75	[347]
Isopropanol	278.15	-	4.89	[348]
Isopropanol	283.15	-	6.777	[348]
Isopropanol	283.16	-	5.632	[347]
Isopropanol	288.14	-	7.083	[347]
Isopropanol	288.15	-	9.07	[348]
Isopropanol	293.15	-	8.967	[347]
Isopropanol	293.15	-	12.56	[348]
Isopropanol	298.15	-	16.62	[348]
Isopropanol	298.18	-	11.55	[347]
Isopropanol	303.15	-	22.36	[348]
Isopropanol	303.17	-	14.57	[347]
Isopropanol	308.13	-	18.93	[347]
Isopropanol	308.15	-	29.02	[348]
Isopropanol	313.15	-	38.1	[348]
Isopropanol	313.16	-	24.16	[347]
Isopropanol	318.1	-	31.92	[347]
Isopropanol	318.15	-	49.01	[348]
Isopropanol	323.14	-	41.81	[347]
Methanol	278.15	-	17.86	[348]
Methanol	283.15	-	23.67	[348]
Methanol	288.15	-	30.55	[348]
Methanol	293.15	-	39.78	[348]
Methanol	298.15	-	50.6	[348]
Methanol	303.15	-	64.44	[348]
Methanol	308.15	-	80.94	[348]
Methanol	313.15	-	102.4	[348]
Methanol	318.15	-	125.3	[348]
Methyl acetate	283.12	-	10.48	[347]
Methyl acetate	288.14	-	13.2	[347]
Methyl acetate	293.15	-	16.24	[347]
Methyl acetate	298.19	-	19.88	[347]
Methyl acetate	303.17	-	23.99	[347]
Methyl acetate	308.14	-	29.33	[347]
Methyl acetate	313.18	-	35.54	[347]
Methyl acetate	318.15	-	42.4	[347]
Methyl acetate	323.13	-	49.39	[347]
Propyl acetate	283.15	-	5.883	[347]
Propyl acetate	288.16	-	7.104	[347]
Propyl acetate	293.09	-	9.26	[347]
Propyl acetate	298.14	-	11.66	[347]
Propyl acetate	303.15	-	14.48	[347]
Propyl acetate	308.17	-	18.21	[347]
Propyl acetate	313.11	-	23.1	[347]
Propyl acetate	318.16	-	28.12	[347]
Propyl acetate	323.1	-	34.39	[347]
Propylene Glycol	278.15	-	7.29	[348]
Propylene Glycol	283.15	-	9.953	[348]
Propylene Glycol	288.15	-	13.47	[348]
Propylene Glycol	293.15	-	17.73	[348]
Propylene Glycol	298.15	-	23.17	[348]
Propylene Glycol	303.15	-	29.9	[348]
Propylene Glycol	308.15	-	38.69	[348]
Propylene Glycol	313.15	-	49.32	[348]
Propylene Glycol	318.15	-	62.97	[348]
Water	278.15	-	0.114	[348]
Water	283.15	-	0.1588	[348]
Water	288.15	-	0.2195	[348]
Water	293.15	-	0.2917	[348]
Water	298.15	-	0.3529	[348]
Water	303.15	-	0.4943	[348]
Water	308.15	-	0.6634	[348]
Water	313.15	-	0.8246	[348]
Water	318.15	-	1.043	[348]

Molecule 3D descriptors

Descriptor	Value
PMI1	1169.9422
PMI2	4241.7882
PMI3	5052.3620
NPR1	0.2316
NPR2	0.8396
RadiusOfGyration	4.1056
InertialShapeFactor	0.0007
Eccentricity	0.9728
Asphericity	0.4597
SpherocityIndex	0.1648
PBF	0.8044