Brivaracetam

Molecular Mass: 212.29 g/mol

Formula: C₁₁H₂₀N₂O₂

Smiles: CCC[C@@H]1CC(=O)N([C@@H](CC)C(N)=O)C1

Synonymes:

Brivaracetam, 357336-20-0, Briviact, UCB 34714, UCB-34714, UCB34714, (2s)-2-[(4r)-2-oxo-4-propylpyrrolidin-1-yl]butanamide, U863JGG2IA, 1-Pyrrolidineacetamide, alpha-ethyl-2-oxo-4-propyl-, (alphaS,4R)-, CHEBI:133013, DTXSID00905081, (2S)-2-((4R)-2-Oxo-4-propylpyrrolidin-1-yl)butanamide, brivaracetamum, RefChem:57048, N03AX23, DTXCID601334183, (2S)-2-((4R)-2-OXO-4-PROPYLTETRAHYDRO-1H-PYRROL-1-YL) BUTANAMIDE, 2-(2-oxo-4-propylpyrrolidin-1-yl)butanamide, MFCD25976668, (S)-2-((R)-2-Oxo-4-propylpyrrolidin-1-yl)butanamide, Rikelta, Brivaracetam [USAN:INN], UNII-U863JGG2IA, Brivaracetam?, (2S)-2-[(4R)-2-oxidanylidene-4-propyl-pyrrolidin-1-yl]butanamide, compound 83alpha, (R)-Atomoxetine, Briviact (TN), 1-Pyrrolidineacetamide, alpha-ethyl-2-oxo-4-propyl-, (alphaS,4R)-, (alphaS,4R)-alpha-Ethyl-2-oxo-4-propyl-1-pyrrolidineacetamide, Brivaracetam, Briviact, UCB 34714, BRIVARACETAM [MI], BRIVARACETAM [INN], BRIVARACETAM [JAN], BRIVARACETAM [USAN], Brivaracetam [EP monograph], BRIVARACETAM [MART.], orb363926, BRIVARACETAM [WHO-DD], SCHEMBL122081, Brivaracetam (JAN/USAN/INN), CHEMBL607400, GTPL9041, AE5 - Anti-epileptic drugs 5, (2S)-2-[(4R)-2-oxo-4-propyl-pyrrolidin-1-yl]butanamide, DEA NO. 2710, MSYKRHVOOPPJKU-BDAKNGLRSA-N, BRIVARACETAM [ORANGE BOOK], GLXC-27574, EX-A2748, BDBM50422531, AKOS027324306, CCG-266666, CS-3418, DB05541, NCGC00390779-02, AC-29289, AS-35277, BB161996, HY-14449, NS00068020, D08879, Q408099, BRD-K00634421-001-01-0, (2S)-2-((4R)-2-oxo-4-n-propyl-1-pyrrolidinyl)butanamide, (2S)-2-[(4R)-2-Oxo-4-propyl-1-pyrrolidinyl]butanamide, (alphaS,4R)-alpha-Ethyl-2-oxo-4-propyl-1-pyrrolidineacetamide, 1-Pyrrolidineacetamide alpha-ethyl-2-oxo-4-propyl-, (alphaS,4R)-

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
1-Propanol	278.15	-	457.6	[352]
1-Propanol	283.15	-	587.0	[352]
1-Propanol	288.15	-	731.0	[352]
1-Propanol	293.15	-	921.1	[352]
1-Propanol	298.15	-	1100.0	[352]
1-Propanol	303.15	-	1311.0	[352]
1-Propanol	308.15	-	1607.0	[352]
1-Propanol	313.15	-	1949.0	[352]
1-Propanol	318.15	-	2503.0	[352]
1-Propanol	323.15	-	2980.0	[352]
Butyl acetate	278.15	-	46.93	[352]
Butyl acetate	283.15	-	56.72	[352]
Butyl acetate	288.15	-	72.34	[352]
Butyl acetate	293.15	-	98.6	[352]
Butyl acetate	298.15	-	147.9	[352]
Butyl acetate	303.15	-	192.7	[352]
Butyl acetate	308.15	-	303.7	[352]
Butyl acetate	313.15	-	418.0	[352]
Butyl acetate	318.15	-	649.3	[352]
Butyl acetate	323.15	-	1091.0	[352]
Ethanol	278.15	-	861.9	[352]
Ethanol	283.15	-	1073.0	[352]
Ethanol	288.15	-	1271.0	[352]
Ethanol	293.15	-	1537.0	[352]
Ethanol	298.15	-	1767.0	[352]
Ethanol	303.15	-	2122.0	[352]
Ethanol	308.15	-	2538.0	[352]
Ethanol	313.15	-	3105.0	[352]
Ethanol	318.15	-	3879.0	[352]
Ethanol	323.15	-	4778.0	[352]
Ethyl acetate	278.15	-	84.79	[352]
Ethyl acetate	283.15	-	125.8	[352]
Ethyl acetate	288.15	-	182.0	[352]
Ethyl acetate	293.15	-	276.4	[352]
Ethyl acetate	298.15	-	386.3	[352]
Ethyl acetate	303.15	-	538.5	[352]
Ethyl acetate	308.15	-	806.3	[352]
Ethyl acetate	313.15	-	1049.0	[352]
Ethyl acetate	318.15	-	1505.0	[352]
Ethyl acetate	323.15	-	2072.0	[352]
Ethyl formate	278.15	-	262.2	[352]
Ethyl formate	283.15	-	340.8	[352]
Ethyl formate	288.15	-	439.8	[352]
Ethyl formate	293.15	-	579.0	[352]
Ethyl formate	298.15	-	757.7	[352]
Ethyl formate	303.15	-	1007.0	[352]
Ethyl formate	308.15	-	1270.0	[352]
Ethyl formate	313.15	-	1659.0	[352]
Ethyl formate	318.15	-	2215.0	[352]
Ethyl formate	323.15	-	2733.0	[352]
Heptane	278.15	-	0.01506	[352]
Heptane	283.15	-	0.02728	[352]
Heptane	288.15	-	0.049	[352]
Heptane	293.15	-	0.06911	[352]
Heptane	298.15	-	0.1176	[352]
Heptane	303.15	-	0.1617	[352]
Heptane	308.15	-	0.2389	[352]
Heptane	313.15	-	0.3518	[352]
Heptane	318.15	-	0.4703	[352]
Heptane	323.15	-	0.6876	[352]
Hexane	278.15	-	0.068	[352]
Hexane	283.15	-	0.1093	[352]
Hexane	288.15	-	0.1459	[352]
Hexane	293.15	-	0.2161	[352]
Hexane	298.15	-	0.29	[352]
Hexane	303.15	-	0.3829	[352]
Hexane	308.15	-	0.5155	[352]
Hexane	313.15	-	0.6524	[352]
Hexane	318.15	-	0.8218	[352]
Hexane	323.15	-	1.151	[352]
Isopropanol	278.15	-	410.4	[352]
Isopropanol	283.15	-	546.4	[352]
Isopropanol	288.15	-	637.6	[352]
Isopropanol	293.15	-	778.2	[352]
Isopropanol	298.15	-	920.0	[352]
Isopropanol	303.15	-	1105.0	[352]
Isopropanol	308.15	-	1413.0	[352]
Isopropanol	313.15	-	1749.0	[352]
Isopropanol	318.15	-	2163.0	[352]
Isopropanol	323.15	-	2790.0	[352]
Methanol	278.15	-	1630.0	[352]
Methanol	283.15	-	2011.0	[352]
Methanol	288.15	-	2357.0	[352]
Methanol	293.15	-	2664.0	[352]
Methanol	298.15	-	3020.0	[352]
Methanol	303.15	-	3689.0	[352]
Methanol	308.15	-	4127.0	[352]
Methanol	313.15	-	5055.0	[352]
Methanol	318.15	-	6393.0	[352]
Methanol	323.15	-	7900.0	[352]
isopropyl acetate	278.15	-	61.75	[352]
isopropyl acetate	283.15	-	82.58	[352]
isopropyl acetate	288.15	-	121.9	[352]
isopropyl acetate	293.15	-	151.1	[352]
isopropyl acetate	298.15	-	220.3	[352]
isopropyl acetate	303.15	-	325.5	[352]
isopropyl acetate	308.15	-	460.6	[352]
isopropyl acetate	313.15	-	708.9	[352]
isopropyl acetate	318.15	-	1005.0	[352]
isopropyl acetate	323.15	-	1448.0	[352]
tert-Butyl methyl ether	278.15	-	14.57	[352]
tert-Butyl methyl ether	283.15	-	21.41	[352]
tert-Butyl methyl ether	288.15	-	33.15	[352]
tert-Butyl methyl ether	293.15	-	61.14	[352]
tert-Butyl methyl ether	298.15	-	92.55	[352]
tert-Butyl methyl ether	303.15	-	149.0	[352]
tert-Butyl methyl ether	308.15	-	216.0	[352]
tert-Butyl methyl ether	313.15	-	367.5	[352]
tert-Butyl methyl ether	318.15	-	706.3	[352]
tert-Butyl methyl ether	323.15	-	1232.0	[352]

Molecule 3D descriptors

Descriptor	Value
PMI1	475.3689
PMI2	1653.4776
PMI3	1777.7900
NPR1	0.2674
NPR2	0.9301
RadiusOfGyration	3.0333
InertialShapeFactor	0.0020
Eccentricity	0.9636
Asphericity	0.4062
SpherocityIndex	0.2400
PBF	0.8179