Tenoxicam

CAS Number: 59804-37-4

Molecular Mass: 337.4 g/mol

Formula: C₁₃H₁₁N₃O₄S₂

Smiles: CN1C(C(=O)Nc2ccccn2)=C(O)c2sccc2S1(=O)=O

Synonymes:

Tenoxicam, tenoxicam, 59804-37-4, Mobiflex, Tilcotil, Tenoxicamum, Ro 12-0068, Ro 12-0068/000, Ro-12-0068, DTXSID8045486, NSC-758397, CHEBI:32192, Z1R9N0A399, 4-Hydroxy-2-methyl-N-2-pyridyl-2H-thieno(2,3-e)-1,2-thiazine-3-carboxamide 1,1-dioxide, Ro-120068000, DTXCID6025486, RO-12-0068/000, RefChem:891355, M01AC02, 4-hydroxy-2-methyl-1,1-dioxo-N-(pyridin-2-yl)-2H-1??-thieno(2,3-e)(1,2)thiazine-3-carboxamide, Alganex, Liman, Tenoxicamum [INN-Latin], 4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide, MFCD00083502, MLS000069830, 4-hydroxy-2-methyl-1,1-dioxo-N-pyridin-2-ylthieno[2,3-e]thiazine-3-carboxamide, 2H-Thieno[2,3-e]-1,2-thiazine-3-carboxamide,4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide, 4-Hydroxy-2-methyl-N-2-pyridinyl-2H-thieno(2,3-e)-1,2-thiazine-3-carboxamide 1,1-dioxide, 4-HYDROXY-2-METHYL-N-2-PYRIDINYL-2H-THIENO[2,3-E]-1,2-THIAZINE-3-CARBOXAMIDE 1,1-DIOXIDE, NCGC00016889-01, SMR000058865, CAS-59804-37-4, 2H-Thieno(2,3-e)-1,2-thiazine-3-carboxamide, 4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide, Octiveran, Rexalgan, 4-Hydroxy-2-methyl-N-pyridin-2-yl-2H-thieno-[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide, Tilcotil (TN), CCRIS 5264, SR-01000721894, BRN 0572193, Dolmen, Tenoxicam (JAN/USAN/INN), UNII-Z1R9N0A399, Mobiflex, , Rexalgan, , Alganex, , Dolmen, , Tenoxicam CRS, Liman, , (4-hydroxy-2-methyl-1,1-dioxothiopheno[2,3-e]1,2-thiazin-3-yl)-N-(2-pyridyl)ca rboxamide, Tenoxicam [USAN:INN:BAN:JAN], Tenoxicam, NSAID, 2H-Thieno[2,3-e]-1,2-thiazine-3-carboxamide, 4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide, Tenoxicam, 4-Hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e]1,2-thiazine-3-carboxamide 1,1-dioxide, Mobiflex, Tenoxicam, Prestwick_849, Tenoxicam(Mobiflex), Tenoxicam (Standard), Ro-120068, Spectrum_001430, TENOXICAM [INN], TENOXICAM [JAN], TENOXICAM [MI], TENOXICAM [USAN], Opera_ID_1757, Prestwick0_000527, Prestwick1_000527, Prestwick2_000527, Prestwick3_000527, Spectrum2_001080, Spectrum3_001563, Spectrum4_000731, Spectrum5_001615, Epitope ID:613457, TENOXICAM [MART.], TENOXICAM [WHO-DD], (3Z)-3-[hydroxy-(pyridin-2-ylamino)methylidene]-2-methyl-1,1-dioxothieno[2,3-e]thiazin-4-one, SCHEMBL25343, SCHEMBL25344, BSPBio_000513, BSPBio_003066, KBioGR_001022, KBioSS_001910, MLS001074071, MLS006011432, BIDD:GT0650, DivK1c_000252, SPECTRUM1503142, SPBio_001100, SPBio_002434, Tenoxicam - Bio-X trade mark, BPBio1_000565, CHEMBL302795, orb1308088, SCHEMBL3692450, CHEMBL3188633, SCHEMBL13448847, TENOXICAM [EP MONOGRAPH], BCBcMAP01_000251, BDBM92332, HMS500M14, HY-B0440R, KBio1_000252, KBio2_001910, KBio2_004478, KBio2_007046, KBio3_002566, Lornoxicam Impurity 5, Tenoxicam, MSK7200, NINDS_000252, HMS1569J15, HMS1923I15, HMS2090P19, HMS2092L20, HMS2096J15, HMS2232K23, HMS3370L01, HMS3656O10, HMS3713J15, HMS3884N04, HMS5081A17, Pharmakon1600-01503142, HY-B0440, Tox21_110666, BBL028173, CCG-40126, EBC-04427, NSC758397, s2512, SBB056362, STK637103, AKOS000282084, AKOS026750148, Tenoxicam degradation impurity standard, Tox21_110666_1, AC-4526, DB00469, FT28033, KS-1313, NSC 758397, IDI1_000252, SMP1_000040, NCGC00016889-02, NCGC00016889-03, NCGC00016889-05, NCGC00016889-06, NCGC00095260-01, NCGC00095260-02, BT166206, SBI-0051780.P002, NS00078018, NS00127421, ST50950119, SW219788-1, C75797, D01767, Q45050, AB00052322-11, AB00052322_12, AB00052322_13, EN300-6487244, F869060, SR-01000721894-2, SR-01000721894-4, Q63395752, Tenoxicam, British Pharmacopoeia (BP) Reference Standard, Z2588038907, Tenoxicam, European Pharmacopoeia (EP) Reference Standard, 4-hydroxy-2-methyl-1,1-dioxo-N-(2-pyridyl)thieno[2,3-e]thiazine-3-carboxamide, 4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-thieno[2,3-e]-1,2-thiazine-3-carboxamide 1,1-dioxide, N-(2-pyridyl)-4-hydroxy-2-methyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxamide 1,1-dioxide, (3e)-3-[hydroxy(pyridin-2-ylamino)methylene]-2-methyl-2,3-dihydro4h-thieno[2,3-e] [1,2]thiazin-4-one-1,1-dioxide, 4-Hydroxy-2-methyl-1,1-dioxo-N-(pyridin-2-yl)-1,2-dihydro-1lambda~6~-thieno[2,3-e][1,2]thiazine-3-carboxamide, 4-hydroxy-2-methyl-1,1-dioxo-N-(pyridin-2-yl)-2H-1lambda6-thieno[2,3-e][1,2]thiazine-3-carboxamide, 4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide1,1-dioxide, 4-Hydroxy-2-methyl-N-pyridin-2-yl-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide (Tenoxicam)

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
1-Butanol	298.15	-	0.2982	[355]
1-Butanol	303.15	-	0.3834	[355]
1-Butanol	308.15	-	0.4869	[355]
1-Butanol	313.15	-	0.5895	[355]
1-Butanol	323.15	-	0.8562	[355]
2-Butanol	298.15	-	0.2246	[355]
2-Butanol	303.15	-	0.3193	[355]
2-Butanol	308.15	-	0.4445	[355]
2-Butanol	313.15	-	0.5858	[355]
2-Butanol	323.15	-	0.9664	[355]
Diethylene Glycol Monoethyl Ether	298.15	-	4.533	[355]
Diethylene Glycol Monoethyl Ether	303.15	-	4.981	[355]
Diethylene Glycol Monoethyl Ether	308.15	-	5.45	[355]
Diethylene Glycol Monoethyl Ether	313.15	-	5.891	[355]
Diethylene Glycol Monoethyl Ether	323.15	-	6.929	[355]
Ethanol	298.15	-	0.2134	[355]
Ethanol	303.15	-	0.2351	[355]
Ethanol	308.15	-	0.2593	[355]
Ethanol	313.15	-	0.2816	[355]
Ethanol	323.15	-	0.3264	[355]
Ethyl acetate	298.15	-	2.327	[355]
Ethyl acetate	303.15	-	2.54	[355]
Ethyl acetate	308.15	-	2.789	[355]
Ethyl acetate	313.15	-	3.048	[355]
Ethyl acetate	323.15	-	3.508	[355]
Ethylene Glycol	298.15	-	1.285	[355]
Ethylene Glycol	303.15	-	1.48	[355]
Ethylene Glycol	308.15	-	1.697	[355]
Ethylene Glycol	313.15	-	1.937	[355]
Ethylene Glycol	323.15	-	2.619	[355]
Isopropanol	298.15	-	0.275	[355]
Isopropanol	303.15	-	0.3887	[355]
Isopropanol	308.15	-	0.5424	[355]
Isopropanol	313.15	-	0.7074	[355]
Isopropanol	323.15	-	1.139	[355]
Propylene Glycol	298.15	-	0.8886	[355]
Propylene Glycol	303.15	-	1.072	[355]
Propylene Glycol	308.15	-	1.251	[355]
Propylene Glycol	313.15	-	1.483	[355]
Propylene Glycol	323.15	-	1.967	[355]
Water	298.15	-	0.07712	[356]
Water	298.15	-	0.07675	[355]
Water	303.15	-	0.0951	[356]
Water	303.15	-	0.09454	[355]
Water	308.15	-	0.1232	[356]
Water	308.15	-	0.1203	[355]
Water	313.15	-	0.1578	[356]
Water	313.15	-	0.1548	[355]
Water	323.15	-	0.259	[356]
Water	323.15	-	0.2554	[355]

Molecule 3D descriptors

Descriptor	Value
PMI1	999.9528
PMI2	3663.6663
PMI3	4356.4230
NPR1	0.2295
NPR2	0.8410
RadiusOfGyration	3.6562
InertialShapeFactor	0.0008
Eccentricity	0.9733
Asphericity	0.4631
SpherocityIndex	0.0843
PBF	0.5503