Finerenone

Molecular Mass: 378.4 g/mol

Formula: C₂₁H₂₂N₄O₃

Smiles: CCOc1ncc(C)c2c1[C@H](c1ccc(C#N)cc1OC)C(C(N)=O)=C(C)N2

Synonymes:

Finerenone, 1050477-31-0, Kerendia, BAY94-8862, (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide, BAY 94-8862, finerenona, DE2O63YV8R, BAY-94-8862, (4S)-4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-1,4-dihydro-2,8-dimethyl-1,6-naphthyridine-3-carboxamide, DTXSID10146928, finerenonum, RefChem:57201, DTXCID5069419, 814-499-5, Finerenone (BAY 94-8862), (S)-4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide, 1,6-Naphthyridine-3-carboxamide, 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-1,4-dihydro-2,8-dimethyl-, (4S)-, Finerenone [USAN:INN], UNII-DE2O63YV8R, Finerenone?, Kerendia (TN), Finerenone, 1,6-Naphthyridine-3-carboxamide, 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-1,4-dihydro-2,8-dimethyl-, (4S)-, (4S)-4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-1,4-dihydro-2,8-dimethyl-1,6-naphthyridine-3-carboxamide, BAY 94-8862, Finerenone, Finerenone (Standard), FINERENONE [INN], FINERENONE [JAN], FINERENONE [USAN], FINERENONE [WHO-DD], Finerenone (JAN/USAN/INN), GTPL8678, orb1306378, SCHEMBL8157011, FINERENONE [ORANGE BOOK], SCHEMBL29623206, SCHEMBL30978927, WLZ3553, GLXC-15655, 1,6-Naphthyridine-3-carboxamide, 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-1,4-dihydro-2,8-dimethyl-, (4S)-, 1,6-Naphthyridine-3-carboxamide, 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-1,4-dihydro-2,8-dimethyl-, (4S)-, EX-A2845, MFCD29047135, HY-111372R, AC-30916, DA-53198, MS-26172, HY-111372, CS-0040097, D10633, F53302, T21395, Q21099046, (4S)-4-(4-cyano-2-methoxy-phenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
Acetone	273.15	-	20.01	[359]
Acetone	278.15	-	21.48	[359]
Acetone	283.15	-	23.58	[359]
Acetone	288.15	-	26.5	[359]
Acetone	293.15	-	28.23	[359]
Acetone	298.15	-	29.66	[359]
Acetone	303.15	-	31.36	[359]
Acetone	308.15	-	33.72	[359]
Acetone	313.15	-	36.53	[359]
Acetonitrile	273.15	-	5.995	[359]
Acetonitrile	278.15	-	7.171	[359]
Acetonitrile	283.15	-	8.148	[359]
Acetonitrile	288.15	-	9.351	[359]
Acetonitrile	293.15	-	10.41	[359]
Acetonitrile	298.15	-	11.88	[359]
Acetonitrile	303.15	-	13.56	[359]
Acetonitrile	308.15	-	15.38	[359]
Acetonitrile	313.15	-	17.36	[359]
Dichloromethane	273.15	-	28.71	[359]
Dichloromethane	278.15	-	30.7	[359]
Dichloromethane	283.15	-	34.01	[359]
Dichloromethane	288.15	-	37.24	[359]
Dichloromethane	293.15	-	39.79	[359]
Dichloromethane	298.15	-	42.78	[359]
Dichloromethane	303.15	-	44.95	[359]
Dichloromethane	308.15	-	47.41	[359]
Ethanol	273.15	-	6.296	[359]
Ethanol	278.15	-	7.623	[359]
Ethanol	283.15	-	8.856	[359]
Ethanol	288.15	-	10.15	[359]
Ethanol	293.15	-	11.84	[359]
Ethanol	298.15	-	13.35	[359]
Ethanol	303.15	-	14.99	[359]
Ethanol	308.15	-	16.71	[359]
Ethanol	313.15	-	19.0	[359]
Ethyl acetate	273.15	-	4.535	[359]
Ethyl acetate	278.15	-	5.052	[359]
Ethyl acetate	283.15	-	5.614	[359]
Ethyl acetate	288.15	-	6.114	[359]
Ethyl acetate	293.15	-	6.574	[359]
Ethyl acetate	298.15	-	7.016	[359]
Ethyl acetate	303.15	-	7.47	[359]
Ethyl acetate	308.15	-	8.027	[359]
Ethyl acetate	313.15	-	8.494	[359]
Isopropanol	273.15	-	1.158	[359]
Isopropanol	278.15	-	1.675	[359]
Isopropanol	283.15	-	2.217	[359]
Isopropanol	288.15	-	2.757	[359]
Isopropanol	293.15	-	3.376	[359]
Isopropanol	298.15	-	4.046	[359]
Isopropanol	303.15	-	4.819	[359]
Isopropanol	308.15	-	5.948	[359]
Isopropanol	313.15	-	7.373	[359]
Methanol	273.15	-	38.38	[359]
Methanol	278.15	-	40.26	[359]
Methanol	283.15	-	42.74	[359]
Methanol	288.15	-	45.66	[359]
Methanol	293.15	-	48.37	[359]
Methanol	298.15	-	51.68	[359]
Methanol	303.15	-	55.64	[359]
Methanol	308.15	-	58.88	[359]
Methanol	313.15	-	62.85	[359]
Methyl acetate	273.15	-	6.24	[359]
Methyl acetate	278.15	-	6.644	[359]
Methyl acetate	283.15	-	7.29	[359]
Methyl acetate	288.15	-	7.99	[359]
Methyl acetate	293.15	-	8.681	[359]
Methyl acetate	298.15	-	9.366	[359]
Methyl acetate	303.15	-	9.939	[359]
Methyl acetate	308.15	-	10.72	[359]
Methyl acetate	313.15	-	11.53	[359]
Methyl ethyl ketone	273.15	-	13.47	[359]
Methyl ethyl ketone	278.15	-	15.01	[359]
Methyl ethyl ketone	283.15	-	16.15	[359]
Methyl ethyl ketone	288.15	-	17.5	[359]
Methyl ethyl ketone	293.15	-	18.68	[359]
Methyl ethyl ketone	298.15	-	19.75	[359]
Methyl ethyl ketone	303.15	-	21.29	[359]
Methyl ethyl ketone	308.15	-	22.57	[359]
Methyl ethyl ketone	313.15	-	24.3	[359]
isopropyl acetate	273.15	-	1.26	[359]
isopropyl acetate	278.15	-	1.519	[359]
isopropyl acetate	283.15	-	1.85	[359]
isopropyl acetate	288.15	-	2.11	[359]
isopropyl acetate	293.15	-	2.359	[359]
isopropyl acetate	298.15	-	2.599	[359]
isopropyl acetate	303.15	-	2.84	[359]
isopropyl acetate	308.15	-	3.101	[359]
isopropyl acetate	313.15	-	3.554	[359]

Molecule 3D descriptors

Descriptor	Value
PMI1	2355.2450
PMI2	3128.3701
PMI3	4082.9853
NPR1	0.5768
NPR2	0.7662
RadiusOfGyration	3.5552
InertialShapeFactor	0.0003
Eccentricity	0.8169
Asphericity	0.0982
SpherocityIndex	0.4925
PBF	1.3142