Levetiracetam

Molecular Mass: 170.21 g/mol

Formula: C₈H₁₄N₂O₂

Smiles: CC[C@@H](C(N)=O)N1CCCC1=O

Synonymes:

Levetiracetam, 102767-28-2, Keppra, (2S)-2-(2-oxopyrrolidin-1-yl)butanamide, Keppra XR, Spritam, UCB-L 059, ucb L059, matever, Levetiracetame, Levetiracetamum, UCB-L059, Elepsia, (S)-alpha-Ethyl-2-oxo-1-pyrrolidineacetamide, Levetiracetam sun, E Keppra, Elepsia XR, Levetiracetam teva, Levetiracetam accord, Levetiracetam actavis, Levetiracetam hospira, 1-Pyrrolidineacetamide, alpha-ethyl-2-oxo-, (alphaS)-, (-)-(S)-alpha-Ethyl-2-oxo-1-pyrrolidineacetamide, UCB-22059, UCB 22059, NSC-760119, Levetiracetam In Sodium Chloride, AGB-101, N03AX14, 44YRR34555, LEVETIRACETAM RATIOPHARM, CHEBI:6437, DTXSID9023207, LEVETIRACETAM ACTAVIS GROUP, 1-Pyrrolidineacetamide, alpha-ethyl-2-oxo-, (S)-, Desitrend, Roweepra, Levetiracetam ER, Etiracetam, R, Etiracetam, S, Levetiracetam oral, Etiracetam, S-, R-isomer Etiracetam, S-isomer Etiracetam, LEVERTIRACETAM, Levetiracetam Injection, RefChem:5943, ucb-L060, UcbL060, Levetiracetam Levetiracetam, Levetiracetam Extended-release, DTXCID503207, ELEPSIA XR 1000 MG, ELEPSIA XR 1500 MG, UCB6474, alpha ethyl 2 oxo 1 Pyrrolidineacetamide, 1-Pyrrolidineacetamide, Alpha-ethyl-2-oxo-,(S)-, 600-348-9, (S)-2-(2-Oxopyrrolidin-1-yl)butanamide, SIB-S1, MFCD03265610, Levetiracetam [INN], Levetiracetamum [INN-Latin], Levroxa, (S)-(-)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide, Leviteracetam, Levipil, Torleva, (S)-Levetiracetam, SMR000466303, Keppra (TN), Levesam 500, Etiracetam levo-isomer, SR-01000759400, s1356, UNII-44YRR34555, HSDB 7528, Levetiracetam CRS, 1-Pyrrolidineacetamide, a-ethyl-2-oxo-, a-Ethyl-2-oxo-1-pyrrolidineacetamide, Etiracetam, UCB 6474, (2RS)-2-(2-Oxopyrrolidin-1-yl)butanamide, Levetiracetam [USAN:USP:INN:BAN], E keppra (TN), (S)-2-(2-Oxo-1-pyrrolidinyl)butyramide, L-059, LEVETIRACETAM [MI], LEVETIRACETAM [JAN], CHEMBL1286, LEVETIRACETAM [HSDB], LEVETIRACETAM [USAN], LEVETIRACETAM [VANDF], MLS000759403, MLS001424069, MLS006010215, BIDD:GT0242, LEVETIRACETAM [MART.], SCHEMBL118843, LEVETIRACETAM [USP-RS], LEVETIRACETAM [WHO-DD], GTPL6826, orb1310850, orb3141186, SCHEMBL6650425, LEVETIRACETAM [EMA EPAR], Levetiracetam (JP19/USP/INN), HPHUVLMMVZITSG-LURJTMIESA-N, Levetiracetam - Bio-X trade mark, Levetiracetam, >=98% (HPLC), Levetiracetam, analytical standard, GLXC-03020, HMS2051D07, HMS2089L20, HMS2235I18, HMS3262H11, HMS3713P16, HMS3884O11, Levetiracetam, 1mg/ml in Methanol, Pharmakon1600-01502265, LEVETIRACETAM [EP IMPURITY], LEVETIRACETAM [ORANGE BOOK], ALBB-027275, HY-B0106, MSK10598, LEVETIRACETAM [EP MONOGRAPH], LEVETIRACETAM [USP IMPURITY], Tox21_500835, BDBM50422542, EBC-06279, LEVETIRACETAM [USP MONOGRAPH], NSC760119, STL388027, Levetiracetam 1.0 mg/ml in Methanol, AKOS015841981, AC-1479, CCG-100928, CS-1854, DB01202, FL24879, KS-1176, LP00835, NC00178, NSC 760119, SDCCGSBI-0633760.P001, NCGC00186028-01, NCGC00186028-13, NCGC00261520-01, (S)-2-(2-oxopyrrolidin-1-yl)butyramide, BL164623, (s)-2-(2-oxopyrrolidin-1-yl) butyramide, (a-S)-a-Ethyl-2-oxo-1-pyrrolidineacetamide, L0234, SW197558-3, C07841, D00709, EN300-244575, AB00639945-06, AB00639945_07, AB00639945_08, F079444, (S)-2-(2-OXO-PYRROLIDIN-1-YL)-BUTYRAMIDE, 1-Pyrrolidineacetamide, |A-ethyl-2-oxo-, (|AS)-, SR-01000759400-4, SR-01000759400-5, BRD-K49404994-001-09-1, BRD-K49404994-001-10-9, BRD-K49404994-001-11-7, Z1255435426, (-)-(S)-.ALPHA.-ETHYL-2-OXO-1-PYRROLIDINEACETAMIDE, 1-Pyrrolidineacetamide, .alpha.-ethyl-2-oxo-, (.alpha.S)-, Levetiracetam Working Standard (Secondary Reference Standard), Levetiracetam, European Pharmacopoeia (EP) Reference Standard, Levetiracetam, United States Pharmacopeia (USP) Reference Standard, (-)-(S)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide (2S)-2-(2-Oxo-pyrrolidin-1-yl)butanamide, Levitiracetam, Pharmaceutical Secondary Standard, Certified Reference Material

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
1,4-Dioxane	288.15	-	14.53	[375]
1,4-Dioxane	293.15	-	18.2	[375]
1,4-Dioxane	298.15	-	22.41	[375]
1,4-Dioxane	303.15	-	28.11	[375]
1,4-Dioxane	308.15	-	34.59	[375]
1,4-Dioxane	313.15	-	42.64	[375]
1,4-Dioxane	318.15	-	52.44	[375]
1,4-Dioxane	323.15	-	64.26	[375]
1-Propanol	283.15	-	39.08	[375]
1-Propanol	288.15	-	48.27	[375]
1-Propanol	293.15	-	58.88	[375]
1-Propanol	298.15	-	70.67	[375]
1-Propanol	303.15	-	84.77	[375]
1-Propanol	308.15	-	101.8	[375]
1-Propanol	313.15	-	122.2	[375]
1-Propanol	318.15	-	145.2	[375]
1-Propanol	323.15	-	173.5	[375]
Acetone	283.15	-	16.52	[375]
Acetone	288.15	-	20.89	[375]
Acetone	293.15	-	26.09	[375]
Acetone	298.15	-	32.73	[375]
Acetone	303.15	-	40.62	[375]
Acetone	308.15	-	50.3	[375]
Acetone	313.15	-	61.87	[375]
Acetone	318.15	-	76.12	[375]
Acetone	323.15	-	93.42	[375]
Acetonitrile	283.15	-	30.17	[375]
Acetonitrile	288.15	-	37.27	[375]
Acetonitrile	293.15	-	45.12	[375]
Acetonitrile	298.15	-	54.93	[375]
Acetonitrile	303.15	-	66.33	[375]
Acetonitrile	308.15	-	79.62	[375]
Acetonitrile	313.15	-	94.84	[375]
Acetonitrile	318.15	-	113.3	[375]
Acetonitrile	323.15	-	135.0	[375]
Cyclohexane	283.15	-	0.02185	[375]
Cyclohexane	288.15	-	0.0304	[375]
Cyclohexane	293.15	-	0.0412	[375]
Cyclohexane	298.15	-	0.0569	[375]
Cyclohexane	303.15	-	0.0763	[375]
Cyclohexane	308.15	-	0.1023	[375]
Cyclohexane	313.15	-	0.1375	[375]
Cyclohexane	318.15	-	0.1835	[375]
Cyclohexane	323.15	-	0.242	[375]
Ethanol	283.15	-	117.5	[375]
Ethanol	288.15	-	141.1	[375]
Ethanol	293.15	-	168.5	[375]
Ethanol	298.15	-	199.4	[375]
Ethanol	303.15	-	236.7	[375]
Ethanol	308.15	-	278.5	[375]
Ethanol	313.15	-	327.9	[375]
Ethanol	318.15	-	385.7	[375]
Ethanol	323.15	-	452.6	[375]
Ethyl acetate	283.15	-	7.513	[375]
Ethyl acetate	288.15	-	9.494	[375]
Ethyl acetate	293.15	-	11.84	[375]
Ethyl acetate	298.15	-	14.77	[375]
Ethyl acetate	303.15	-	18.11	[375]
Ethyl acetate	308.15	-	22.22	[375]
Ethyl acetate	313.15	-	27.23	[375]
Ethyl acetate	318.15	-	33.22	[375]
Ethyl acetate	323.15	-	40.35	[375]
Isopropanol	283.15	-	26.13	[375]
Isopropanol	288.15	-	33.38	[375]
Isopropanol	293.15	-	42.01	[375]
Isopropanol	298.15	-	51.89	[375]
Isopropanol	303.15	-	64.86	[375]
Isopropanol	308.15	-	80.37	[375]
Isopropanol	313.15	-	99.02	[375]
Isopropanol	318.15	-	122.7	[375]
Isopropanol	323.15	-	152.7	[375]
Methanol	283.15	-	376.9	[375]
Methanol	288.15	-	455.9	[375]
Methanol	293.15	-	547.6	[375]
Methanol	298.15	-	655.3	[375]
Methanol	303.15	-	778.0	[375]
Methanol	308.15	-	920.7	[375]
Methanol	313.15	-	1086.4	[375]
Methanol	318.15	-	1278.8	[375]
Methanol	323.15	-	1499.8	[375]
Toluene	283.15	-	1.979	[375]
Toluene	288.15	-	2.692	[375]
Toluene	293.15	-	3.537	[375]
Toluene	298.15	-	4.785	[375]
Toluene	303.15	-	6.257	[375]
Toluene	308.15	-	8.304	[375]
Toluene	313.15	-	11.03	[375]
Toluene	318.15	-	14.89	[375]
Toluene	323.15	-	20.3	[375]

Molecule 3D descriptors

Descriptor	Value
PMI1	426.9939
PMI2	671.0795
PMI3	750.3116
NPR1	0.5691
NPR2	0.8944
RadiusOfGyration	2.3302
InertialShapeFactor	0.0021
Eccentricity	0.8223
Asphericity	0.0997
SpherocityIndex	0.4923
PBF	0.9324