Ganciclovir

CAS Number: 82410-32-0

Molecular Mass: 255.23 g/mol

Formula: C₉H₁₃N₅O₄

Smiles: Nc1nc2c(ncn2COC(CO)CO)c(=O)[nH]1

Synonymes:

Ganciclovir, ganciclovir, 82410-32-0, Gancyclovir, Vitrasert, Zirgan, BW-759U, Ganciclovirum, RS-21592, BW 759U, Cymevene, Virgan, Cymevan, 2'-Nor-2'-deoxyguanosine, 9-((2-Hydroxy-1-(hydroxymethyl)ethoxy)methyl)guanine, 9-[(1,3-Dihydroxy-2-propoxy)methyl]guanine, P9G3CKZ4P5, 9-((1,3-Dihydroxy-2-propoxy)methyl)guanine, NSC-759656, 2-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-6,9-dihydro-3H-purin-6-one, DTXSID8041032, CHEBI:465284, 2-amino-9-(1,3-dihydroxypropan-2-yloxymethyl)-1H-purin-6-one, 2-(6-Amino-purin-9-ylmethoxy)-propane-1,3-diol, 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-1H-purin-6(9H)-one, 6H-Purin-6-one, 2-amino-1,9-dihydro-9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)-, DTXCID6021032, 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-9H-purin-6-ol, 2-amino-9-(1,3-dihydroxypropan-2-yloxymethyl)-3H-purin-6-one, 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-3H-purin-6(9H)-one, 2-Amino-9-(2-hydroxy-1-hydroxymethyl-ethoxymethyl)-1,9-dihydro-purin-6-one, 2-amino-9-(2-hydroxy-1-hydroxymethylethoxymethyl)-6,9-dihydro-1H-6-purinone, 9-[[2-Hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine, Nordeoxyguanosine, NSC716361, Ganzyk-rtu, 2-amino-9-(((1,3-dihydroxypropan-2-yl)oxy)methyl)-6,9-dihydro-3H-purin-6-one, RefChem:922069, 2'NDG, Ganciclovir, Monosodium Salt, J05AB06, S01AD09, 2-Amino-1,9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)-6H-purin-6-one, Cytovene, Hydroxyacyclovir, 2-Amino-9-(((1,3-dihydroxypropan-2-yl)oxy)methyl)-1H-purin-6(9H)-one, C9H13N5O4, 2'-NDG, MFCD00870588, Natclovir, 9-(1,3-DIHYDROXY-PROPOXYMETHANE)GUANINE, GA2, 2-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-1,9-dihydro-6H-purin-6-one, MLS000028481, Guanine, 9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)-, s1878, NCGC00015471-02, HHEMG, SMR000058324, Biolf 62, Ganciclovirum [Latin], CAS-82410-32-0, 2-amino-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-3H-purin-6-one, 2-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-6,9-dihydro-1H-purin-6-one, GCV, Citovirax, Cymeven, BW-B 759U, DRG-0018, 2-Amino-9-(((1,3-dihydroxypropan-2-yl)oxy)methyl)-6,9-dihydro-1H-purin-6-one, Vitrasert (TN), Cytovene (TN), CCRIS 9212, HSDB 6512, SR-01000075894, GCV & MSL, UNII-P9G3CKZ4P5, Ganciclovir (JAN/USP/INN), 2-((2-amino-6-hydroxy-9H-purin-9-yl)methoxy)propane-1,3-diol, 2-[(2-amino-6-hydroxy-9H-purin-9-yl)methoxy]propane-1,3-diol, Ganciclovir CRS, 2-amino-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-1H-purin-6-one, 2-amino-9-(((1,3-dihydroxypropan-2-yl)oxy)methyl)-1,9-dihydro-6H-purin-6-one, 2-Amino-1,9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)-6-H-purin-6-one, BW-795, MB3795, Prestwick_1068, ST-605, Zirgan (TN), GCV & 1110U81, Ganciclovir [USAN:USP:INN:BAN:JAN], Ganciclovir (Standard), Opera_ID_284, GANCICLOVIR [MI], Prestwick0_000839, Prestwick1_000839, Prestwick2_000839, Prestwick3_000839, GANCICLOVIR [INN], GANCICLOVIR [JAN], Lopac-G-2536, BIOLF62, 3,5-Di-O-tosylthymidine, GANCICLOVIR [HSDB], GANCICLOVIR [USAN], CHEMBL182, EC 627-054-3, G 2536, GANCICLOVIR [VANDF], SCHEMBL3033, SCHEMBL3034, 2-Amino-1,9-dihydro-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6H-purin-6-one, GANCICLOVIR [MART.], Lopac0_000539, 2'-Nor-2'-deoxyguanosine, , BSPBio_000797, GANCICLOVIR [USP-RS], GANCICLOVIR [WHO-DD], MLS001077349, BIDD:GT0783, SPBio_002718, GANCICLOVIR [EMA EPAR], BPBio1_000877, orb1310384, Ganciclovir - Bio-X trade mark, SCHEMBL14491348, BDBM85707, GANCICLOVIR [EP IMPURITY], GANCICLOVIR [ORANGE BOOK], IRSCQMHQWWYFCW-UHFFFAOYSA-N, 2-[(2-amino-6-hydroxypurin-9-yl)methoxy]propane-1,3-diol, GANCICLOVIR [EP MONOGRAPH], GLXC-07993, HMS1570H19, HMS2090K08, HMS2097H19, HMS2235C21, HMS3259B13, HMS3261L19, HMS3371H01, HMS3604L19, HMS3655M18, HMS3714H19, HMS5080O17, Pharmakon1600-01502362, GANCICLOVIR [USP MONOGRAPH], MSK10028, NSC_3454, Tox21_110160, Tox21_500539, 2-(2-Amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol, BBL029078, BDBM50237614, EBC-07889, EBC-13406, HY-13637R, NSC759656, PDSP1_000816, PDSP2_000803, SBB066292, STK801910, STL514515, AKOS004119898, AKOS026749928, AKOS037492029, Tox21_110160_1, Valganciclovir hydrochloride impurity a, AC-8069, CCG-204629, CS-2014, DB01004, FG16550, Ganciclovir, >=99% (HPLC), powder, KS-1065, LP00539, NC00647, NSC 759656, SDCCGSBI-0050522.P002, SMP2_000038, NCGC00015471-01, NCGC00015471-03, NCGC00015471-04, NCGC00015471-05, NCGC00015471-06, NCGC00015471-08, NCGC00015471-16, NCGC00093928-01, NCGC00093928-02, NCGC00168567-01, NCGC00188980-01, NCGC00261224-01, 9-(1,3-dihydroxy-2propoxymethyl)guanine, BG164496, HY-13637, SY027981, 9-(1,3-dihydroxy-2-propoxymethyl)guanine, CAS_82410-32-0, 9-(1,3-dihydroxy-2-propoxymethyl)-guanine, 9-(1,3-Dihydroxy-2-propoxymethyl)guanine, , EU-0100539, G0315, NS00003516, SW197135-3, T0688, EN300-49857, C07019, D00333, Ganciclovir 100 microg/mL in Acetonitrile:Water, 9-[[(1,3-Dihydroxy-2-propyl)oxy]methyl]guanine, F212141, Ganciclovir, Antibiotic for Culture Media Use Only, Q417640, SR-01000721941, Q-201148, SR-01000075894-1, SR-01000075894-4, SR-01000721941-3, BRD-K22662435-001-17-5, BRD-K22662435-001-18-3, BRD-K22662435-001-19-1, Z594284200, Ganciclovir, European Pharmacopoeia (EP) Reference Standard, VALGANCICLOVIR HYDROCHLORIDE IMPURITY A [USP IMPURITY], Ganciclovir, United States Pharmacopeia (USP) Reference Standard, 2-Amino-1,9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]6H-purin-6-one, 2-amino-9-{[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl}hydropurin-6-one, Ganciclovir, Pharmaceutical Secondary Standard, Certified Reference Material, 2-amino-9-{[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl}-1,9-dihydro-6H-purin-6-one, Ganciclovir, 1.0 mg/mL (1% 1M HCl in Methanol), certified reference material, Guanine, 9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)- and MSL, neutralizing monoclonal antibody

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
1-Butanol	278.15	-	0.6309	[382]
1-Butanol	283.15	-	0.6528	[382]
1-Butanol	288.15	-	0.6788	[382]
1-Butanol	293.15	-	0.7077	[382]
1-Butanol	298.15	-	0.7416	[382]
1-Butanol	303.15	-	0.7846	[382]
1-Butanol	308.15	-	0.8317	[382]
1-Butanol	313.15	-	0.8852	[382]
1-Butanol	318.15	-	0.9433	[382]
1-Propanol	278.15	-	0.6648	[382]
1-Propanol	283.15	-	0.6912	[382]
1-Propanol	288.15	-	0.721	[382]
1-Propanol	293.15	-	0.7537	[382]
1-Propanol	298.15	-	0.7901	[382]
1-Propanol	303.15	-	0.8312	[382]
1-Propanol	308.15	-	0.8756	[382]
1-Propanol	313.15	-	0.9243	[382]
1-Propanol	318.15	-	0.9813	[382]
Acetone	278.15	-	0.0012	[382]
Acetone	283.15	-	0.0015	[382]
Acetone	288.15	-	0.0019	[382]
Acetone	293.15	-	0.0025	[382]
Acetone	298.15	-	0.0032	[382]
Acetone	303.15	-	0.0038	[382]
Acetone	308.15	-	0.00467	[382]
Acetone	313.15	-	0.0056	[382]
Acetone	318.15	-	0.0069	[382]
Acetonitrile	278.15	-	0.06243	[382]
Acetonitrile	283.15	-	0.06782	[382]
Acetonitrile	288.15	-	0.0731	[382]
Acetonitrile	293.15	-	0.0795	[382]
Acetonitrile	298.15	-	0.0878	[382]
Acetonitrile	303.15	-	0.0956	[382]
Acetonitrile	308.15	-	0.1041	[382]
Acetonitrile	313.15	-	0.1122	[382]
Acetonitrile	318.15	-	0.1214	[382]
Ethanol	278.15	-	0.4001	[382]
Ethanol	283.15	-	0.4284	[382]
Ethanol	288.15	-	0.4593	[382]
Ethanol	293.15	-	0.493	[382]
Ethanol	298.15	-	0.5335	[382]
Ethanol	303.15	-	0.5729	[382]
Ethanol	308.15	-	0.6203	[382]
Ethanol	313.15	-	0.6722	[382]
Ethanol	318.15	-	0.7278	[382]
Ethyl acetate	278.15	-	6.0 × 10⁻⁴	[382]
Ethyl acetate	283.15	-	8.0 × 10⁻⁴	[382]
Ethyl acetate	288.15	-	0.0012	[382]
Ethyl acetate	293.15	-	0.0016	[382]
Ethyl acetate	298.15	-	0.002	[382]
Ethyl acetate	303.15	-	0.0026	[382]
Ethyl acetate	308.15	-	0.0032	[382]
Ethyl acetate	313.15	-	0.0039	[382]
Ethyl acetate	318.15	-	0.0047	[382]
Isopropanol	278.15	-	0.2112	[382]
Isopropanol	283.15	-	0.23	[382]
Isopropanol	288.15	-	0.2515	[382]
Isopropanol	293.15	-	0.2766	[382]
Isopropanol	298.15	-	0.3005	[382]
Isopropanol	303.15	-	0.3272	[382]
Isopropanol	308.15	-	0.3519	[382]
Isopropanol	313.15	-	0.3801	[382]
Isopropanol	318.15	-	0.412	[382]
Methanol	278.15	-	0.4705	[382]
Methanol	283.15	-	0.5068	[382]
Methanol	288.15	-	0.5527	[382]
Methanol	293.15	-	0.6016	[382]
Methanol	298.15	-	0.6577	[382]
Methanol	303.15	-	0.7242	[382]
Methanol	308.15	-	0.7996	[382]
Methanol	313.15	-	0.8778	[382]
Methanol	318.15	-	0.9568	[382]
Toluene	278.15	-	4.0 × 10⁻⁴	[382]
Toluene	283.15	-	5.0 × 10⁻⁴	[382]
Toluene	288.15	-	5.0 × 10⁻⁴	[382]
Toluene	293.15	-	6.0 × 10⁻⁴	[382]
Toluene	298.15	-	7.0 × 10⁻⁴	[382]
Toluene	303.15	-	8.0 × 10⁻⁴	[382]
Toluene	308.15	-	9.0 × 10⁻⁴	[382]
Toluene	313.15	-	0.0011	[382]
Toluene	318.15	-	0.0012	[382]

Molecule 3D descriptors

Descriptor	Value
PMI1	613.3808
PMI2	2723.9970
PMI3	2993.0190
NPR1	0.2049
NPR2	0.9101
RadiusOfGyration	3.5215
InertialShapeFactor	0.0015
Eccentricity	0.9788
Asphericity	0.5085
SpherocityIndex	0.2471
PBF	0.7921