β-Artemether
CAS Number: 71963-77-4
Molecular Mass: 298.37 g/mol
Formula: C16H26O5
Smiles: CO[C@H]1O[C@@H]2O[C@@]3(C)CC[C@H]4[C@H](C)CC[C@@H]([C@H]1C)[C@@]24OO3
Synonymes:
β-Artemether, Artemether, 71963-77-4, beta-Artemether, Dihydroartemisinin methyl ether, Artemetero, Artemetherum, Artesaph, Falcidol, Malartem, Paluther, Gvither, Methyl-dihydroartemisinine, Artemisininelactol methyl ether, Artemetheri, Larither, beta-Dihydroartemisinin methyl ether, SM 224, Dihydroqinghaosu methyl ether, DTXSID7040651, CHEBI:195280, C7D6T3H22J, (1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane, DTXCID30819889, SM224, O-Methyldihydroartemisinine, (1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecane, NSC-665970, NSC-759820, 10-methoxy-1,5,9-trimethyl-(1R,4S,5R,8S,9R,10S,12R,13R)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane, beta Arthemeter, COARTEM COMPONENT ARTEMETHER, alpha Artemether, (1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo(10.3.1.0^(4,13).0^(8,13))hexadecane, (1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo(10.3.1.04,13.08,13)hexadecane, 10-methoxy-1,5,9-trimethyl-(1R,4S,5R,8S,9R,10S,12R,13R)-11,14,15,16-tetraoxatetracyclo(10.3.1.04,13.08,13)hexadecane, 3,12-Epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin, decahydro-10-methoxy-3,6,9-trimethyl-, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-, 3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, decahydro-10-methoxy-3,6,9-trimethyl-, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-, RefChem:560091, O Methyldihydroartemisinine, P01BE02, 663-549-0, 695-829-3, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, Artenam, C16H26O5, Artemos, CPD000469218, SM-224, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-3H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene, .beta.-Artemether, Artemetero [INN-Spanish], Artemetherum [INN-Latin], methoxy(trimethyl)[?], (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin, Dihydroquinghaosu methyl ether, HSDB 7456, NSC 665970, UNII-C7D6T3H22J, Artimist, Qinghao, beta artemether, Artemether [USAN:INN:BAN], Artemether RS, NSC665970, NCGC00164591-01, Dihydroartemisinin impurity g, MLS001424249, Artemether (JAN/USAN/INN), CHEMBL566534, GTPL9955, orb1308984, orb3025906, SCHEMBL1650501, Artemether, >=98% (HPLC), GLXC-03969, HMS2052L09, HMS2232J21, HY-N0402, Coartem (artemether + lumefantrine), Tox21_112217, BDBM50248200, EBC-11189, AKOS026750084, CCG-101180, DB06697, FA17991, NC00430, NCGC00164591-11, 3,12-Epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin, decahydro-10-methoxy-3,6,9-trimethyl-, (3-alpha,5a-beta,6-beta,8a-beta,9-alpha,12-beta,12aR)-, (+)-, Artemether 100 microg/mL in Acetonitrile, SMR000469218, CAS-71963-77-4, NS00001253, D02483, EN300-122380, AB00698368-05, AB00698368_06, F795474, Q416199, BRD-K39621635-001-05-5, Z1541759910, Artemether, United States Pharmacopeia (USP) Reference Standard, (1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0, {4,13}.0, {8,13}]hexadecane, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-Methoxy-3,6,9-trimethyldecahydro-12H-3,12-epoxypyrano[4,3-j][1,2]benzodioxepine, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepine, (3r,5as,6r,8as,9r,10s,12r,12ar)-decahydro-10methoxy-3,6,9-trimethyl-3,12-epoxy-12h-pyrano[4,3-j]-1,2benzodioxepin, D8Z
Bioactivity: -
Solubility in Different Solvents
| Solvent | Temperature [K] | Crystal form | Solubility [mg/mL] | Reference |
|---|---|---|---|---|
| Ethanol | 289.05 | - | 211.5 | [424] |
| Ethanol | 290.85 | - | 228.2 | [424] |
| Ethanol | 293.95 | - | 264.5 | [424] |
| Ethanol | 296.95 | - | 320.7 | [424] |
| Ethanol | 299.05 | - | 371.6 | [424] |
| Ethanol | 301.05 | - | 419.3 | [424] |
| Ethanol | 303.95 | - | 501.3 | [424] |
| Ethanol | 306.95 | - | 622.3 | [424] |
| Ethanol | 308.45 | - | 662.9 | [424] |
| Ethanol | 310.45 | - | 768.4 | [424] |
| Ethanol | 313.2 | - | 983.9 | [424] |
| Ethanol | 316.25 | - | 1241.8 | [424] |
| Ethanol | 318.95 | - | 1668.5 | [424] |
| Ethanol | 322.65 | - | 2278.0 | [424] |
| Ethanol | 326.05 | - | 3109.6 | [424] |
| Ethanol | 328.65 | - | 3887.7 | [424] |
| Methanol | 289.45 | - | 200.2 | [424] |
| Methanol | 291.15 | - | 224.2 | [424] |
| Methanol | 294.05 | - | 261.2 | [424] |
| Methanol | 296.95 | - | 309.4 | [424] |
| Methanol | 299.05 | - | 355.1 | [424] |
| Methanol | 300.75 | - | 399.4 | [424] |
| Methanol | 303.55 | - | 504.9 | [424] |
| Methanol | 306.35 | - | 651.3 | [424] |
| Methanol | 308.25 | - | 792.9 | [424] |
| Methanol | 310.15 | - | 949.1 | [424] |
| Methanol | 312.95 | - | 1261.1 | [424] |
| Methanol | 315.65 | - | 1643.7 | [424] |
| Methanol | 317.35 | - | 2046.2 | [424] |
| Methanol | 319.45 | - | 3019.1 | [424] |
| Methanol | 322.05 | - | 3917.4 | [424] |
Molecule 3D descriptors
| Descriptor | Value |
|---|---|
| PMI1 | 1191.6296 |
| PMI2 | 1545.2811 |
| PMI3 | 2081.3501 |
| NPR1 | 0.5725 |
| NPR2 | 0.7424 |
| RadiusOfGyration | 2.8415 |
| InertialShapeFactor | 0.0006 |
| Eccentricity | 0.8199 |
| Asphericity | 0.1037 |
| SpherocityIndex | 0.4406 |
| PBF | 1.0461 |