Triamterene

CAS Number: 396-01-0

Molecular Mass: 253.26 g/mol

Formula: C₁₂H₁₁N₇

Smiles: Nc1nc(N)c2nc(-c3ccccc3)c(N)nc2n1

Synonymes:

Triamterene, triamterene, 396-01-0, 6-phenylpteridine-2,4,7-triamine, 2,4,7-Triamino-6-phenylpteridine, Dyrenium, Dytac, Pterophene, Triamteren, Diurene, Noridil, Pterofen, Taturil, Teridin, Triteren, Ademine, Jatropur, Noridyl, Triamteril, Urocaudal, Teriam, Diren, Ditak, Dyren, Tri-Span, 6-Phenyl-2,4,7-pteridinetriamine, 2,4,7-Pteridinetriamine, 6-phenyl-, Ademin(e), SK&F 8542, Triamterenum, Triamterena, SKF 8542, 6-Phenyl-2,4,7-triaminopteridine, NSC-77625, Pteridine, 2,4,7-triamino-6-phenyl-, 2,4,7-Triamino-6-fenilpteridina, Triamtereno, DTXSID6021373, SK-8542, SK&F-8542, CHEBI:9671, WS821Z52LQ, NSC77625, NSC-639359, DTXCID001373, 5-26-17-00447 (Beilstein Handbook Reference), NSC639359, Triamterene Capsules, RefChem:58580, C03DB02, 206-904-3, Ademin, Triampur, Trispan, C12H11N7, MFCD00006708, NSC 77625, Triamterene (Standard), Diucelpin, Diuteren, Masuharmin, Triamizide, Triamthiazid, Amteren, Dinazide, Diutensat, Dyberzide, Dytenzide, Esiteren, Hidiurese, Hydrene, Hypertorr, Jenateren, Kalspare, Nephral, Renezide, Reviten, Tricilone, Triurene, Uretren, Diarol, Isobar, Trizid, Anjal, Dazid, Turfa, Apo-triazide, Thiazid Wolff, NCI-C56042, NCGC00016016-10, CAS-396-01-0, Triazide, Fluss 40, SALI-PUREN, Triamterenum [INN-Latin], Triamterena [INN-Spanish], Dyrenium (TN), BRN 0266723, CCRIS 5872, Pteridine deriv. 11, HSDB 3405, 2,4,7-Triamino-6-fenilpteridina [Italian], NCI C56042, SR-01000002968, EINECS 206-904-3, NSC 639359, UNII-WS821Z52LQ, Adernine, Pterophene, , Triamterene?, AI3-60017, Urocaudal, , Dyrenium, , Jatropur, , Pterofen, , Triampur, , Triamterene CRS, Dytac, , Tri-Span, , Prestwick_480, Dyazide (Salt/Mix), Triamterene [USAN:USP:INN:BAN:JAN], Spectrum_000508, Triamterene, >=99%, TRIAMTERENE [MI], Prestwick0_000034, Prestwick1_000034, Prestwick2_000034, Prestwick3_000034, Spectrum2_000938, Spectrum3_001372, Spectrum4_000366, Spectrum5_001034, Lopac-T-4143, TRIAMTERENE [INN], TRIAMTERENE [JAN], TRIAMTERENE [HSDB], TRIAMTERENE [IARC], TRIAMTERENE [USAN], CHEMBL585, Epitope ID:613460, T 4143, TRIAMTERENE [VANDF], NCIOpen2_004741, TRIAMTERENE [MART.], Lopac0_001196, Oprea1_825704, SCHEMBL40707, BSPBio_000127, BSPBio_002924, KBioGR_000831, KBioSS_000988, TRIAMTERENE [USP-RS], TRIAMTERENE [WHO-DD], MLS000069431, BIDD:GT0534, DivK1c_000433, SPECTRUM1500589, SPBio_000876, SPBio_002048, BDBM6644, BPBio1_000141, GTPL4329, orb2281211, orb3025005, Triamterene (JP18/USP/INN), 2,7-Triamino-6-phenylpteridine, 6-Phenyl-2,7-triaminopteridine, SCHEMBL10586653, SCHEMBL29531410, HMS501F15, HY-B0575R, KBio1_000433, KBio2_000988, KBio2_003556, KBio2_006124, KBio3_002144, TRIAMTERENE [ORANGE BOOK], NINDS_000433, HMS1568G09, HMS2092O17, HMS2095G09, HMS2232B04, HMS3259C08, HMS3263P13, HMS3371D10, HMS3652E10, HMS3712G09, HMS5082A10, Pharmakon1600-01500589, TRIAMTERENE [EP MONOGRAPH], TRIAMTERENE [USP IMPURITY], 2,7-Pteridinetriamine, 6-phenyl-, Pteridine,4,7-triamino-6-phenyl-, TRIAMTERENE [USP MONOGRAPH], DYAZIDE COMPONENT TRIAMTERENE, HY-B0575, MAXZIDE COMPONENT TRIAMTERENE, MSK10265, Tox21_110283, Tox21_202021, Tox21_302833, Tox21_501196, CCG-40090, EBC-03774, NSC757367, s4080, SBB017574, STK300348, AKOS003790819, Tox21_110283_1, DB00384, FT28388, LP01196, NC00544, NSC-757367, SDCCGSBI-0051163.P004, IDI1_000433, SMP1_000147, NCGC00016016-01, NCGC00016016-02, NCGC00016016-03, NCGC00016016-04, NCGC00016016-05, NCGC00016016-06, NCGC00016016-07, NCGC00016016-08, NCGC00016016-09, NCGC00016016-11, NCGC00016016-12, NCGC00016016-13, NCGC00016016-14, NCGC00016016-15, NCGC00016016-16, NCGC00016016-18, NCGC00016016-28, NCGC00016016-29, NCGC00023458-03, NCGC00023458-04, NCGC00023458-05, NCGC00023458-06, NCGC00023458-07, NCGC00256495-01, NCGC00259570-01, NCGC00261881-01, AC-14066, AS-12471, SMR000059118, ST093702, SBI-0051163.P003, DB-049442, AB00052116, CS-0695001, EU-0101196, NS00010256, SW196688-3, Triamterene 1.0 mg/ml in Dimethyl Sulfoxide, D00386, D95706, EN300-119540, WLN: T66 BN DN GN JNJ CZ EZ HR& IZ, 2,4-DIAMINO-6-PHENYL-7-PTERIDINYLAMINE, AB00052116_13, AB00052116_14, Q221520, SR-01000002968-2, SR-01000002968-4, SR-01000002968-6, BRD-K92049597-001-05-9, BRD-K92049597-001-10-9, BRD-K92049597-001-19-0, BRD-K92049597-001-20-8, Z275128596, 2,7-Diimino-6-phenyl-1,2,3,7-tetrahydro-4-pteridinamine, Triamterene, British Pharmacopoeia (BP) Reference Standard, Triamterene, European Pharmacopoeia (EP) Reference Standard, Triamterene, United States Pharmacopeia (USP) Reference Standard, Triamterene, Pharmaceutical Secondary Standard, Certified Reference Material

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
1,2-Dichloroethane	283.15	-	0.0056	[431]
1,2-Dichloroethane	288.15	-	0.0075	[431]
1,2-Dichloroethane	293.15	-	0.0113	[431]
1,2-Dichloroethane	298.15	-	0.01669	[431]
1,2-Dichloroethane	303.15	-	0.0239	[431]
1,2-Dichloroethane	308.15	-	0.0337	[431]
1,2-Dichloroethane	313.15	-	0.0532	[431]
1,2-Dichloroethane	318.15	-	0.074	[431]
1,2-Dichloroethane	323.15	-	0.1099	[431]
1-Butanol	283.15	-	0.00926	[431]
1-Butanol	288.15	-	0.0148	[431]
1-Butanol	293.15	-	0.0224	[431]
1-Butanol	298.15	-	0.0317	[431]
1-Butanol	303.15	-	0.044	[431]
1-Butanol	308.15	-	0.0574	[431]
1-Butanol	313.15	-	0.08439	[431]
1-Butanol	318.15	-	0.1168	[431]
1-Butanol	323.15	-	0.1742	[431]
1-Propanol	283.15	-	0.01449	[431]
1-Propanol	288.15	-	0.0208	[431]
1-Propanol	293.15	-	0.0309	[431]
1-Propanol	298.15	-	0.0483	[431]
1-Propanol	303.15	-	0.0679	[431]
1-Propanol	308.15	-	0.0941	[431]
1-Propanol	313.15	-	0.1286	[431]
1-Propanol	318.15	-	0.1748	[431]
1-Propanol	323.15	-	0.231	[431]
2-Methoxyethanol	283.15	-	6.122	[431]
2-Methoxyethanol	288.15	-	8.028	[431]
2-Methoxyethanol	293.15	-	10.88	[431]
2-Methoxyethanol	298.15	-	14.57	[431]
2-Methoxyethanol	303.15	-	19.37	[431]
2-Methoxyethanol	308.15	-	25.28	[431]
2-Methoxyethanol	313.15	-	33.68	[431]
2-Methoxyethanol	318.15	-	44.46	[431]
2-Methoxyethanol	323.15	-	57.32	[431]
Acetonitrile	283.15	-	0.01233	[431]
Acetonitrile	288.15	-	0.01669	[431]
Acetonitrile	293.15	-	0.0249	[431]
Acetonitrile	298.15	-	0.0383	[431]
Acetonitrile	303.15	-	0.055	[431]
Acetonitrile	308.15	-	0.0758	[431]
Acetonitrile	313.15	-	0.1139	[431]
Acetonitrile	318.15	-	0.1618	[431]
Acetonitrile	323.15	-	0.2309	[431]
Dimethyl sulfoxide	293.15	-	7.202	[431]
Dimethyl sulfoxide	298.15	-	10.02	[431]
Dimethyl sulfoxide	303.15	-	13.51	[431]
Dimethyl sulfoxide	308.15	-	18.11	[431]
Dimethyl sulfoxide	313.15	-	23.99	[431]
Dimethyl sulfoxide	318.15	-	31.69	[431]
Dimethyl sulfoxide	323.15	-	41.47	[431]
Ethyl acetate	283.15	-	0.0076	[431]
Ethyl acetate	288.15	-	0.0118	[431]
Ethyl acetate	293.15	-	0.0189	[431]
Ethyl acetate	298.15	-	0.0243	[431]
Ethyl acetate	303.15	-	0.0363	[431]
Ethyl acetate	308.15	-	0.0494	[431]
Ethyl acetate	313.15	-	0.0705	[431]
Ethyl acetate	318.15	-	0.09949	[431]
Ethyl acetate	323.15	-	0.1512	[431]
Isobutanol	283.15	-	0.008	[431]
Isobutanol	288.15	-	0.0111	[431]
Isobutanol	293.15	-	0.0168	[431]
Isobutanol	298.15	-	0.0238	[431]
Isobutanol	303.15	-	0.03338	[431]
Isobutanol	308.15	-	0.04604	[431]
Isobutanol	313.15	-	0.0686	[431]
Isobutanol	318.15	-	0.1012	[431]
Isobutanol	323.15	-	0.1443	[431]
Isopropanol	283.15	-	0.0068	[431]
Isopropanol	288.15	-	0.0118	[431]
Isopropanol	293.15	-	0.0163	[431]
Isopropanol	298.15	-	0.0244	[431]
Isopropanol	303.15	-	0.0346	[431]
Isopropanol	308.15	-	0.04797	[431]
Isopropanol	313.15	-	0.0675	[431]
Isopropanol	318.15	-	0.0945	[431]
Isopropanol	323.15	-	0.134	[431]
Methanol	283.15	-	0.1838	[431]
Methanol	288.15	-	0.2712	[431]
Methanol	293.15	-	0.3977	[431]
Methanol	298.15	-	0.5236	[431]
Methanol	303.15	-	0.7859	[431]
Methanol	308.15	-	1.036	[431]
Methanol	313.15	-	1.463	[431]
Methanol	318.15	-	1.942	[431]
Methanol	323.15	-	2.709	[431]
Water	283.15	-	0.0151	[431]
Water	288.15	-	0.0181	[431]
Water	293.15	-	0.0211	[431]
Water	298.15	-	0.0251	[431]
Water	303.15	-	0.0302	[431]
Water	308.15	-	0.0369	[431]
Water	313.15	-	0.04359	[431]
Water	318.15	-	0.0523	[431]
Water	323.15	-	0.064	[431]

Molecule 3D descriptors

Descriptor	Value
PMI1	530.2851
PMI2	2382.9013
PMI3	2834.3851
NPR1	0.1871
NPR2	0.8407
RadiusOfGyration	3.3685
InertialShapeFactor	0.0016
Eccentricity	0.9823
Asphericity	0.5415
SpherocityIndex	0.0803
PBF	0.4494