Levofloxacin

Molecular Mass: 361.4 g/mol

Formula: C₁₈H₂₀FN₃O₄

Smiles: C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23

Synonymes:

Levofloxacin, LEVOFLOXACIN, 100986-85-4, Levaquin, Quixin, (-)-Ofloxacin, Iquix, Cravit, (S)-Ofloxacin, Levofloxacine, Tavanic, L-Ofloxacin, Levofloxacino, Levofloxacinum, Elequine, Oftaquix, Floxacin, Levofloxacin Anhydrous, DR-3355, Nofaxin, Volequin, Quinsair, NSC-758709, RIX4E89Y14, (S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, DTXSID0041060, LEVAQUIN IN DEXTROSE 5% IN PLASTIC CONTAINER, RWJ-25213, CHEBI:63598, (2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid, (3S)-(-)-9-Fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid, 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 2,3-dihydro-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (S)-, (S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzooxazine-6-carboxylic acid, Ofloxacin s-(-)-form hemihydrate, Anhydrous, Levofloxacin, lLevofloxacin, Evoxil, (2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo(7.3.1.0^(5,13))trideca-5(13),6,8,11-tetraene-11-carboxylic acid, (2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo(7.3.1.05,13)trideca-5(13),6,8,11-tetraene-11-carboxylic acid, (2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13),6,8,11-tetraene-11-carboxylic acid, (3S)-(-)-9-Fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido(1,2,3-de)(1,4)benzoxazine-6-carboxylic acid, (S)-(-)-9-Fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido(1,2,3-de)(1,4)benzooxazine-6-carboxylic acid, Ofloxacin S-(-)-, RefChem:5945, (-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, hemihydrate, 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, hydrate (2:1), (S)-, Levofloxacin in 5% Dextrose, Levofloxacin, sodium chloride, DTXCID8021060, J01MA12, S01AE05, LEVOFLOXACIN IN DEXTROSE 5% IN PLASTIC CONTAINER, 600-146-0, 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic Acid, 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (S)-, 6GNT3Y5LMF, Levofloxacin (as hemihydrate), Levofloxacin hemihydrate, Ofloxacin, (S)-, Ofloxacin S-(-)-form, (S)-(-)-Ofloxacin, MFCD00865049, Levofloxacin (Levaquin), MP-376, Levofloxacin (INN), Levaquin (TN), 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (3S)-, (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, MMV687798, (S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, LEVOFLOXACIN [INN], LFX, Levofloxacine [INN-French], Levofloxacinum [INN-Latin], Levofloxacino [INN-Spanish], DR3355, HR 355, Aeroquin, Unibiotic, Venaxan, Levofloxacin [USAN:INN:JAN], Loxof, RWJ 25213-097, (-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazin-yl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, SMR000466387, Cravit (TN), S-(-)-Ofloxacin, CCRIS 4074, UNII-RIX4E89Y14, Levofiexacin, Ofloxcacin, S-ofloxacin, s1940, HSDB 8028, Cravit IV, Anhydrous Ofloxacin, DR-3355: L-isomer of ofloxacin, LevofloxacinLevaquin, (S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, HR-355, MP 376, Spectrum_001719, CPD000466387, Levofloxacin (Standard), Levofloxacin (anhydrous), Levofloxacine (anhydrous), Levofloxacino (anhydrous), Spectrum2_001676, Spectrum3_000995, Spectrum4_001123, Spectrum5_001438, SCHEMBL15397, BSPBio_002689, KBioGR_001605, KBioSS_002199, (-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, fluoro-methyl-(4-methylpiperazin-1-yl)-oxo-[?]carboxylic acid, MLS000759524, MLS001165709, MLS001423977, LEVOFLOXACIN [WHO-DD], SPECTRUM1504260, SPBio_001891, orb1300652, orb3141259, GTPL10911, HY-B0330R, KBio2_002199, KBio2_004767, KBio2_007335, KBio3_001909, MSK5725, HMS1922J07, HMS2051G04, HMS2090O10, HMS2093E18, HMS2232G06, Pharmakon1600-01504260, EX-A1488, HY-B0330, Levofloxacin, >=98.0% (HPLC), BDBM50366826, CCG-39093, DE-108, EBC-11226, MSK5725-100D, MSK5725-100M, NSC755604, NSC758709, OFLOXACIN S-(-)-FORM [MI], AKOS008901361, AKOS015895104, AC-7593, AL10796, DB01137, NC00094, NSC 758709, NSC-755604, NCGC00178529-01, NCGC00178529-02, NCGC00178529-03, NCGC00178529-06, (S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, AS-31796, SY007392, Levofloxacin Solution in DMSO, 100ug/mL, Levofloxacin, analytical reference material, SBI-0206768.P001, L0193, Levofloxacin Solution in Methanol, 100ug/mL, NS00010154, C07660, D08120, AB00171657-12, AB00171657-13, AB00171657_14, AB00171657_15, F387019, Q424193, SR-05000001999, SR-05000001999-1, BRD-K09471561-001-06-7, BRD-K09471561-001-18-2, Z1590790198, ()-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1, ()-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1, (2S)-7-Fluoro-2-methyl-6-(4-methylpiperazin-4-ium-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylate, (3S)-9-Fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, (S)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]-benzoxazine-6-carboxylic acid

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
1-Butanol	288.15	-	5.771	[42]
1-Butanol	293.15	-	6.928	[42]
1-Butanol	298.15	-	8.635	[42]
1-Butanol	303.15	-	10.51	[42]
1-Butanol	308.15	-	13.7	[42]
1-Butanol	313.15	-	17.52	[42]
1-Butanol	318.15	-	23.37	[42]
1-Butanol	323.15	-	30.67	[42]
1-Butanol	328.15	-	35.19	[42]
1-Propanol	288.15	-	5.304	[42]
1-Propanol	293.15	-	5.83	[42]
1-Propanol	298.15	-	6.843	[42]
1-Propanol	303.15	-	8.657	[42]
1-Propanol	308.15	-	11.15	[42]
1-Propanol	313.15	-	13.49	[42]
1-Propanol	318.15	-	17.7	[42]
1-Propanol	323.15	-	21.15	[42]
1-Propanol	328.15	-	26.82	[42]
Acetic acid	298.15	-	372.0	[42]
Acetic acid	303.15	-	383.8	[42]
Acetic acid	308.15	-	399.1	[42]
Acetic acid	313.15	-	412.8	[42]
Acetic acid	318.15	-	427.7	[42]
Acetic acid	323.15	-	440.6	[42]
Acetic acid	328.15	-	449.7	[42]
Ethanol	288.15	-	3.55	[42]
Ethanol	293.15	-	4.909	[42]
Ethanol	298.15	-	6.594	[42]
Ethanol	303.15	-	8.22	[42]
Ethanol	308.15	-	10.88	[42]
Ethanol	313.15	-	15.43	[42]
Ethanol	318.15	-	19.4	[42]
Ethanol	323.15	-	24.77	[42]
Ethanol	328.15	-	31.49	[42]
Ethyl acetate	288.15	-	7.186	[42]
Ethyl acetate	293.15	-	7.799	[42]
Ethyl acetate	298.15	-	8.13	[42]
Ethyl acetate	303.15	-	9.001	[42]
Ethyl acetate	308.15	-	10.24	[42]
Ethyl acetate	313.15	-	11.64	[42]
Ethyl acetate	318.15	-	13.6	[42]
Ethyl acetate	323.15	-	17.25	[42]
Ethyl acetate	328.15	-	19.59	[42]
Isopropanol	288.15	-	2.09	[42]
Isopropanol	293.15	-	2.576	[42]
Isopropanol	298.15	-	3.01	[42]
Isopropanol	303.15	-	3.839	[42]
Isopropanol	308.15	-	4.796	[42]
Isopropanol	313.15	-	6.263	[42]
Isopropanol	318.15	-	7.531	[42]
Isopropanol	323.15	-	9.93	[42]
Isopropanol	328.15	-	12.26	[42]

Molecule 3D descriptors

Descriptor	Value
PMI1	1094.6828
PMI2	4613.4328
PMI3	5431.6704
NPR1	0.2015
NPR2	0.8494
RadiusOfGyration	3.9260
InertialShapeFactor	0.0008
Eccentricity	0.9795
Asphericity	0.5135
SpherocityIndex	0.1610
PBF	0.7365