Etodolac

CAS Number: 41340-25-4

Molecular Mass: 287.35 g/mol

Formula: C₁₇H₂₁NO₃

Smiles: CCc1cccc2c3c([nH]c12)C(CC)(CC(=O)O)OCC3

Synonymes:

Etodolac, etodolac, 41340-25-4, Etodolic acid, Lodine, Ultradol, Lodine XL, Edolan, Ramodar, Etodolaco, Zedolac, AY-24236, Etodolacum, Tedolan, AY-24,236, AY 24236, Eccoxolac, Flancox, Napilac, Lodin xl, 1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid, (rs)-etodolic acid, DTXSID9020615, Lodine SR, 1,3,4,9-Tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid, 1,8-Diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid, Pyrano[3,4-b]indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-, NSC-282126, CHEBI:4909, Pyrano(3,4-b)indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-, NIH-9918, NSC282126, DTXCID30615, AY-24-236, (+-)-1,8-Diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid, (1,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetic acid, 2M36281008, 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-ylacetic acid, Ebretin, Etolyn, 1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indol-1-ylacetic acid, Etopan xl, EtoGesic Tablets, (1,8-Diethyl-1,3,4,9-tetrahydro-pyrano(3,4-b)indol-1-yl)-acetic acid, Etodolac ER, RefChem:55167, AY 24,236, M01AB08, Etogesic Sterile Injectable Solution, 2-((1RS)-1,8-Diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indol-1-yl)acetic acid, rac-Etodolac, 2-(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid, 2-(1,8-diethyl-4,9-dihydro-3H-pyrano[3,4-b]indol-1-yl)acetic acid, MFCD00133313, CHEMBL622, (+/-)-ETODOLAC, MLS000028474, 2-{1,8-diethyl-1H,3H,4H,9H-pyrano[3,4-b]indol-1-yl}acetic acid, (1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid, SMR000058443, Etodolacum [INN-Latin], Etodolaco [INN-Spanish], Hypen, (+/-)-1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid, CCRIS 3923, SR-01000000100, NSC 282126, Etogesic, Osteluc, etodolac o, Etodolie acid, rac Etodolac, 2-(1,8-Diethyl-1H,3H,4H,9H-pyrano[3,4-b]indol-1-yl)acetic acid, Etodlic Acid, Etodolac CRS, Etodolac [USAN:USP:INN:BAN], RAK-591, NCGC00016849-01, Prestwick_209, CAS-41340-25-4, Etodolac (Standard), Lodine (TN), UNII-2M36281008, Spectrum_001244, ETODOLAC [USAN], ETODOLAC [INN], ETODOLAC [JAN], ETODOLAC [MI], Etodolac impurity mixture, ETODOLAC [VANDF], Opera_ID_1774, Prestwick0_000231, Prestwick1_000231, Prestwick2_000231, Prestwick3_000231, Spectrum2_001387, Spectrum3_001429, Spectrum4_000410, Spectrum5_001347, ETODOLAC [MART.], Epitope ID:613427, ETODOLAC [USP-RS], ETODOLAC [WHO-DD], (RS)-2-(1,8-Diethyl-4,9-dihydro-3H-pyrano[3,4-b]indol-1-yl)acetic acid, SCHEMBL3903, Lopac0_000479, BSPBio_000301, BSPBio_003138, KBioGR_000680, KBioSS_001724, Etodolac - Bio-X trade mark, MLS001077315, MLS006011566, DivK1c_000147, ETODOLAC [GREEN BOOK], SPECTRUM1501005, Etodolac (JP18/USP/INN), SPBio_001374, SPBio_002222, ETODOLAC [ORANGE BOOK], BPBio1_000333, GTPL7185, orb1310080, orb3025562, ETODOLAC [EP MONOGRAPH], ETODOLAC [USP MONOGRAPH], SCHEMBL29385172, HMS500H09, KBio1_000147, KBio2_001724, KBio2_004292, KBio2_006860, KBio3_002358, MSK8008, (R)-2-(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid, NINDS_000147, HMS1568P03, HMS1921B09, HMS2092O20, HMS2095P03, HMS2231D04, HMS3259P10, HMS3261O20, HMS3374G09, HMS3712P03, HMS5079D11, Pharmakon1600-01501005, BBC19746, Tox21_110644, Tox21_202218, Tox21_500479, 1,8-diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indole-1-acetic acid, BDBM50016799, CCG-39005, EBC-11162, Etodolac for peak identification CRS, HY-76251R, MSK8008-100A, NSC757821, Pyrano(3,4-b)indole-1-acetic acid, 1,3,4,9-tetrahydro-1,8-diethyl-, AKOS015838610, MSK8008-1000A, Pyrano(3,4-b)indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-(+-)-, Tox21_110644_1, AC-4231, CS-0832, DB00749, FR27516, LP00479, NC00718, NSC-757821, SDCCGSBI-0050463.P004, IDI1_000147, NCGC00015399-03, NCGC00015399-04, NCGC00015399-05, NCGC00015399-06, NCGC00015399-07, NCGC00015399-08, NCGC00015399-09, NCGC00015399-11, NCGC00015399-12, NCGC00015399-13, NCGC00015399-15, NCGC00015399-16, NCGC00015399-26, NCGC00015399-27, NCGC00089769-02, NCGC00089769-03, NCGC00089769-04, NCGC00089769-05, NCGC00089769-06, NCGC00089769-07, NCGC00259767-01, NCGC00261164-01, BR164431, HY-76251, SY057989, SBI-0050463.P003, AB00052194, E0858, Etodolac Solution in Acetonitrile, 100ug/mL, EU-0100479, NS00010209, Etodolac Solution in Acetonitrile, 1000ug/mL, C06991, D00315, E 0516, EN300-119494, Pyrano[3, 1,8-diethyl-1,3,4,9-tetrahydro-, AB00052194_17, F358075, Q2465218, SR-01000000100-2, SR-01000000100-4, SR-01000000100-7, BRD-A74667430-001-05-3, BRD-A74667430-001-15-2, BRD-A74667430-001-23-6, 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid, Etodolac, European Pharmacopoeia (EP) Reference Standard, F2173-0681, Z1521549186, Etodolac, United States Pharmacopeia (USP) Reference Standard, 1,8-Diethyl-1,3,4,9-tetrahydropyranol[3,4-b]indole-1-acetic acid, 1,8-DIETHYL-1,3,4,9-TETRAHYDROPYRANO(3,4-B)INDOL-1-ACETIC ACID, Pyrano(3,4,b)indole-1-acetic acid, 1,3,4,9-tetrahydro-1,8-diethyl-, Etodolac for peak identification, European Pharmacopoeia (EP) Reference Standard, PYRANO(3,4-B)INDOLE-1-ACETIC ACID, 1,8-DIETHYL-1,3,4,9-TETRAHYDRO-(+/-)-

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
1-Butanol	278.15	-	122.7	[448]
1-Butanol	283.15	-	139.6	[448]
1-Butanol	288.15	-	160.7	[448]
1-Butanol	293.15	-	190.9	[448]
1-Butanol	298.15	-	226.3	[448]
1-Butanol	303.15	-	263.1	[448]
1-Butanol	308.15	-	295.8	[448]
1-Butanol	313.15	-	339.9	[448]
1-Butanol	318.15	-	404.9	[448]
1-Butanol	323.15	-	475.2	[448]
1-Propanol	278.15	-	138.1	[448]
1-Propanol	283.15	-	158.0	[448]
1-Propanol	288.15	-	182.7	[448]
1-Propanol	293.15	-	222.9	[448]
1-Propanol	298.15	-	264.7	[448]
1-Propanol	303.15	-	308.9	[448]
1-Propanol	308.15	-	351.1	[448]
1-Propanol	313.15	-	403.8	[448]
1-Propanol	318.15	-	482.4	[448]
1-Propanol	323.15	-	562.6	[448]
Acetone	278.15	-	412.1	[448]
Acetone	283.15	-	446.3	[448]
Acetone	288.15	-	482.5	[448]
Acetone	293.15	-	520.0	[448]
Acetone	298.15	-	564.9	[448]
Acetone	303.15	-	608.2	[448]
Acetone	308.15	-	660.0	[448]
Acetone	313.15	-	707.2	[448]
Acetone	318.15	-	761.7	[448]
Acetone	323.15	-	810.5	[448]
Amyl Acetate	278.15	-	93.64	[448]
Amyl Acetate	283.15	-	103.8	[448]
Amyl Acetate	288.15	-	115.2	[448]
Amyl Acetate	293.15	-	128.3	[448]
Amyl Acetate	298.15	-	137.2	[448]
Amyl Acetate	303.15	-	152.4	[448]
Amyl Acetate	308.15	-	165.7	[448]
Amyl Acetate	313.15	-	184.8	[448]
Amyl Acetate	318.15	-	204.5	[448]
Amyl Acetate	323.15	-	226.3	[448]
Butyl acetate	278.15	-	105.5	[448]
Butyl acetate	283.15	-	117.6	[448]
Butyl acetate	288.15	-	130.5	[448]
Butyl acetate	293.15	-	145.8	[448]
Butyl acetate	298.15	-	158.4	[448]
Butyl acetate	303.15	-	174.2	[448]
Butyl acetate	308.15	-	192.6	[448]
Butyl acetate	313.15	-	214.6	[448]
Butyl acetate	318.15	-	237.2	[448]
Butyl acetate	323.15	-	262.4	[448]
Dichloromethane	278.15	-	45.28	[448]
Dichloromethane	283.15	-	57.34	[448]
Dichloromethane	288.15	-	71.2	[448]
Dichloromethane	293.15	-	86.9	[448]
Dichloromethane	298.15	-	104.2	[448]
Dichloromethane	303.15	-	123.0	[448]
Isobutanol	278.15	-	72.41	[448]
Isobutanol	283.15	-	85.62	[448]
Isobutanol	288.15	-	101.9	[448]
Isobutanol	293.15	-	123.5	[448]
Isobutanol	298.15	-	154.4	[448]
Isobutanol	303.15	-	194.6	[448]
Isobutanol	308.15	-	233.2	[448]
Isobutanol	313.15	-	286.8	[448]
Isobutanol	318.15	-	350.5	[448]
Isobutanol	323.15	-	423.1	[448]
Isobutyl Acetate	278.15	-	98.35	[448]
Isobutyl Acetate	283.15	-	108.9	[448]
Isobutyl Acetate	288.15	-	121.2	[448]
Isobutyl Acetate	293.15	-	133.8	[448]
Isobutyl Acetate	298.15	-	148.9	[448]
Isobutyl Acetate	303.15	-	160.7	[448]
Isobutyl Acetate	308.15	-	177.6	[448]
Isobutyl Acetate	313.15	-	198.5	[448]
Isobutyl Acetate	318.15	-	221.9	[448]
Isobutyl Acetate	323.15	-	250.8	[448]
Isopropanol	278.15	-	105.0	[448]
Isopropanol	283.15	-	120.2	[448]
Isopropanol	288.15	-	142.4	[448]
Isopropanol	293.15	-	174.4	[448]
Isopropanol	298.15	-	216.2	[448]
Isopropanol	303.15	-	266.4	[448]
Isopropanol	308.15	-	313.0	[448]
Isopropanol	313.15	-	366.2	[448]
Isopropanol	318.15	-	445.8	[448]
Isopropanol	323.15	-	530.1	[448]
Methyl acetate	278.15	-	180.0	[448]
Methyl acetate	283.15	-	200.9	[448]
Methyl acetate	288.15	-	223.8	[448]
Methyl acetate	293.15	-	246.7	[448]
Methyl acetate	298.15	-	265.5	[448]
Methyl acetate	303.15	-	297.6	[448]
Methyl acetate	308.15	-	322.7	[448]
Methyl acetate	313.15	-	357.1	[448]
Methyl acetate	318.15	-	392.7	[448]
Methyl acetate	323.15	-	434.1	[448]
Toluene	278.15	-	3.226	[448]
Toluene	283.15	-	4.017	[448]
Toluene	288.15	-	5.166	[448]
Toluene	293.15	-	6.515	[448]
Toluene	298.15	-	8.538	[448]
Toluene	303.15	-	10.57	[448]
Toluene	308.15	-	13.39	[448]
Toluene	313.15	-	17.31	[448]
Toluene	318.15	-	22.23	[448]
Toluene	323.15	-	28.59	[448]

Molecule 3D descriptors

Descriptor	Value
PMI1	1217.2925
PMI2	1949.2879
PMI3	2595.2604
NPR1	0.4690
NPR2	0.7511
RadiusOfGyration	3.1663
InertialShapeFactor	0.0006
Eccentricity	0.8832
Asphericity	0.1718
SpherocityIndex	0.4049
PBF	1.0186