Cinnarizine
CAS Number: 298-57-7
Molecular Mass: 368.5 g/mol
Formula: C26H28N2
Smiles: C(=C/c1ccccc1)\CN1CCN(C(c2ccccc2)c2ccccc2)CC1
Synonymes:
Cinnarizine, cinnarizine, 298-57-7, Stugeron, Dimitron, Folcodal, Labyrin, Midronal, Mitronal, Stutgeron, Stutgin, Glanil, Sepan, Aplactan, Cinazyn, Cinarizine, Cinnageron, Cinaperazine, Cinarizina, Aplexal, Cinnarizinum, Cinnipirine, Processine, Sedatromin, Spaderizine, Carecin, Cerebolan, Cinnacet, Corathiem, Denapol, Giganten, Hilactan, Ixertol, Katoseran, Siptazin, Artate, Eglen, Olamin, Votegol, Zepamol, 1-Cinnamyl-4-(diphenylmethyl)piperazine, 516 MD, R 516, R 1575, Stunarone, 1-Benzhydryl-4-cinnamylpiperazin, R-516, 1-(Diphenylmethyl)-4-(3-phenyl-2-propenyl)piperazine, R-1575, 3DI2E1X18L, 516-MD, NSC-758400, 1-(diphenylmethyl)-4-(3-phenylprop-2-en-1-yl)piperazine, DTXSID3022821, CHEBI:31403, 5-23-01-00233 (Beilstein Handbook Reference), 1-(di(phenyl)methyl)-4-(3-phenylprop-2-enyl)piperazine, 1-[di(phenyl)methyl]-4-(3-phenylprop-2-enyl)piperazine, cinnarizina, Stugeron Forte, Stugeron fte, cinnarizin von ct, Marzine r.f., Cinnarizin-ratiopharm, Von Ct, Cinnarizin, Cinnarizin Ratiopharm, Mylan travel sickness, Cinnarizine L Tartrate, RefChem:577233, Dihydrochloride Cinnarizine, DTXCID50809707, N07CA02, MD516, R516, 206-064-8, Dimitronal, Toliman, Lazeta, 1-Benzhydryl-4-cinnamylpiperazine, Cerepar, 16699-20-0, 1-(diphenylmethyl)-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine, Piperazine, 1-(diphenylmethyl)-4-(3-phenyl-2-propenyl)-, 1-benzhydryl-4-[(E)-3-phenylprop-2-enyl]piperazine, (Z)-Cinnarizine, C26H28N2, 1-benzhydryl-4-[(E)-cinnamyl]piperazine, CHEMBL43064, 1-trans-Cinnamyl-4-diphenylmethylpiperazine, MLS000028498, Piperazine, 1-cinnamyl-4-(diphenylmethyl)-, 1-(diphenylmethyl)-4-(3-phenyl-2-propenyl)-piperazine, Libotasin, Senoger, SMR000058307, Cero-Aterin, MFCD00056037, PIPERAZINE, 1-(DIPHENYLMETHYL)-4-(3-PHENYL-2-PROPEN-1-YL)-, Cinarizina [INN-Spanish], Cinnarizinum [INN-Latin], DTXCID802821, 4-((2E)-3-phenylprop-2-enyl)-1-(diphenylmethyl)piperazine, Apotomin, Stonoron, Cinnarizine [USAN:INN:BAN:JAN], SR-01000003093, EINECS 206-064-8, MD 516, BRN 0626121, UNII-3DI2E1X18L, Cinnarizine (JAN/USAN/INN), Cinnarizine?, Aplactan, , Mitronal, , Cinnarizine CRS, N-Benzhydryl-N'-cinnamylpiperazine, NCGC00015246-02, CAS-298-57-7, Cinnarizine, powder, Prestwick_115, Piperazine, (E)-, 1-(Diphenylmethyl)-4-(3-phenyl-2-propen-1-yl)piperazine, Cinnarizine (Standard), CINNARIZINE [MI], Opera_ID_1776, Prestwick2_000278, Prestwick3_000278, CINNARIZINE [INN], CINNARIZINE [JAN], CINNARIZINE [USAN], C 5270, CINNARIZINE [MART.], Lopac0_000314, SCHEMBL44957, BSPBio_000156, CINNARIZINE [WHO-DD], MLS001148649, MLS002207295, MLS002222167, BPBio1_000172, GTPL9072, orb1310183, cid_1547484, HY-B1090R, CINNARIZINE [EP IMPURITY], DTXSID80859311, CHEBI:131176, CINNARIZINE [EP MONOGRAPH], GLXC-06142, HMS1568H18, HMS2095H18, HMS2234B20, HMS3260P10, HMS3712H18, HMS3885F20, HMS5083E22, component of Emesazine (Salt/Mix), HY-B1090, MSK10646, Tox21_110109, Tox21_500314, BDBM50017657, EBC-85024, NSC290687, NSC771642, SBB057016, STK216257, AKOS002134299, Stugeron|Dimitronal|Stutgin|Cinarizine, Tox21_110109_1, CCG-204409, CS-4656, FC20452, KS-5155, LP00314, NSC 758400, NSC-290687, NSC-771642, SDCCGSBI-0050302.P002, QTL1_000023, NCGC00018187-03, NCGC00018187-04, NCGC00018187-05, NCGC00018187-06, NCGC00018187-07, NCGC00018187-09, NCGC00018187-14, NCGC00021488-03, NCGC00021488-04, NCGC00021488-05, NCGC00260999-01, LS-15144, ST069378, EU-0100314, NS00006812, S4727, D01295, D89561, EN300-18169892, F814438, L001227, Q775073, 1-Benzhydryl-4-[3-phenyl-2-propenyl]piperazine #, doi:10.14272/DERZBLKQOCDDDZ-JLHYYAGUSA-N.1, SR-01000003093-2, SR-01000003093-6, BRD-K07220430-001-03-6, BRD-K07220430-001-18-4, BRD-K07220430-001-19-2, BRD-K74927006-001-01-2, (E)-1-(Diphenylmethyl)-4-(3-phenylprop-2-enyl)piperazine, Cinnarizine, European Pharmacopoeia (EP) Reference Standard, N90
Bioactivity: -
Solubility in Different Solvents
| Solvent | Temperature [K] | Crystal form | Solubility [mg/mL] | Reference |
|---|---|---|---|---|
| 1-Butanol | 288.5 | - | 11.07 | [450] |
| 1-Butanol | 293.5 | - | 14.17 | [450] |
| 1-Butanol | 298.4 | - | 16.57 | [450] |
| 1-Butanol | 303.3 | - | 19.99 | [450] |
| 1-Butanol | 308.3 | - | 24.23 | [450] |
| 1-Butanol | 313.2 | - | 32.01 | [450] |
| Acetonitrile | 288.5 | - | 6.204 | [450] |
| Acetonitrile | 293.5 | - | 7.378 | [450] |
| Acetonitrile | 298.4 | - | 9.563 | [450] |
| Acetonitrile | 303.3 | - | 10.95 | [450] |
| Acetonitrile | 308.3 | - | 14.05 | [450] |
| Acetonitrile | 313.2 | - | 18.68 | [450] |
| Butyl acetate | 288.5 | - | 43.62 | [450] |
| Butyl acetate | 293.5 | - | 56.11 | [450] |
| Butyl acetate | 298.4 | - | 64.22 | [450] |
| Butyl acetate | 303.3 | - | 77.24 | [450] |
| Butyl acetate | 308.3 | - | 95.82 | [450] |
| Butyl acetate | 313.2 | - | 121.3 | [450] |
| Isopropanol | 288.5 | - | 3.1 | [450] |
| Isopropanol | 293.5 | - | 3.908 | [450] |
| Isopropanol | 298.4 | - | 4.765 | [450] |
| Isopropanol | 303.3 | - | 6.056 | [450] |
| Isopropanol | 308.3 | - | 7.827 | [450] |
| Isopropanol | 313.2 | - | 9.817 | [450] |
Molecule 3D descriptors
| Descriptor | Value |
|---|---|
| PMI1 | 1844.1938 |
| PMI2 | 6572.9927 |
| PMI3 | 7324.3550 |
| NPR1 | 0.2518 |
| NPR2 | 0.8974 |
| RadiusOfGyration | 4.6214 |
| InertialShapeFactor | 0.0005 |
| Eccentricity | 0.9678 |
| Asphericity | 0.4274 |
| SpherocityIndex | 0.2940 |
| PBF | 1.2125 |