Clopidogrel hydrogen sulfate

CAS Number: 120202-66-6

Molecular Mass: 419.9 g/mol

Formula: C₁₆H₁₈ClNO₆S₂

Smiles: COC(=O)[C@H](c1ccccc1Cl)N1CCc2sccc2C1.O=S(=O)(O)O

Synonymes:

Clopidogrel hydrogen sulfate, Clopidogrel bisulfate, 120202-66-6, CLOPIDOGREL SULFATE, Clopidogrel bisulphate, Clopidogrel hemisulfate, clopidogrel hydrogen sulphate, Clopidogrel BMS, Isocover, Pidogrel, Clopidogrel-bgr, Clopidogrel-bms, Clopidogrel teva, SR 25990C, Clopidogrel zentiva, Clopidogrel (as bisulfate), SR-25990C, Clopidogrel ratiopharm, 08I79HTP27, CLOPIDOGREL (AS HYDROGEN SULFATE), DTXSID601016080, DUOCOVER COMPONENT CLOPIDOGREL BISULFATE, DUOPLAVIN COMPONENT CLOPIDOGREL BISULFATE, Thieno(3,2-c)pyridine-5(4H)-acetic acid, alpha-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (S)-, sulfate (1:1), CLOPIDOGREL/ACETYLSALICYCLIC ACID TEVA COMPONENT CLOPIDOGREL BISULFATE, CHEBI:3759, Clopidogrel 75mg, RefChem:54857, DTXCID2026024, 686-767-8, Methyl (2S)-2-(2-chlorophenyl)-2-(6,7-dihydrothieno(3,2-c)pyridin-5(4H)-yl)acetate monosulfate, Plavix, (S)-methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate sulfate, S-(+)-Clopidogrel Hydrogen Sulfate, Clopidogrel (hydrogen sulfate), Clopidogrel (Plavix), MFCD00876395, 144077-07-6, Thieno[3,2-c]pyridine-5(4H)-acetic acid,a-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (aS)-, sulfate (1:1), C16H18ClNO6S2, PM-103, methyl (2S)-2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate, sulfuric acid, Myogrel, Clopidogrel hydrogensulfate, Plavix (TN), methyl (S)-2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate sulfate, Clopidogrel sulphate, Plavitor, Osvix, (S)-(+)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyrid-5-yl)acetate sulfate, CHEMBL1083385, sulfuric acid methyl (2S)-2-(2-chlorophenyl)-2-{4H,5H,6H,7H-thieno[3,2-c]pyridin-5-yl}acetate, Clopidogrel Bisulfate [USAN], UNII-08I79HTP27, Clopidogrel bisulfate [USAN:USP], Isocover (TN), 120202-66-6 (sulfate), Methyl (S)-2-(2-Chlorophenyl)-2-[6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]acetate Sulfate, Clopidogrel bisolfato, bisulfato de clopidogrel, bissulfato de clopidogrel, Clopido grel hemisulfate, (+) Clopidogrel Bisulfate, Methyl alphaS-(2-chlorophenyl)-6,7-dihydrothieno(3,2-c)pyridine-5(4H)-acetate sulfate (1:1), Clopidogrel bisulfate (USP), Clopidogrel sulfate (JP18), SCHEMBL33556, SCHEMBL33558, SPECTRUM1503710, MDCO-157, orb1310861, Clopidogrel hydrogen sulfate CRS, CLOPIDOGREL SULFATE [JAN], GLXC-07573, HMS1922G16, HMS2093I13, HMS3884G15, Pharmakon1600-01503710, Clopidogrel sulfate tablets (JP18), CCG-39568, CLOPIDOGREL BISULFATE [VANDF], EBC-07538, HY-17459R, MFCD05865229, NSC758613, s1415, T0182L, CLOPIDOGREL BISULFATE [MART.], AKOS015900408, CLOPIDOGREL BISULFATE [USP-RS], CLOPIDOGREL BISULFATE [WHO-DD], Clopidogrel for system suitability CRS, AC-2135, CS-1882, DV-7314, FC11669, FC20513, KS-1045, methyl (2S)-2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate sulfate, CLOPIDOGREL HYDROGEN SULFATE [MI], 111GE004, BC164326, HY-17459, Methyl (+)-(S)-alpha-(o-chlorophenyl)-6,7-dihydrothieno(3,2-c)pyridine-5(4H)-acetate, sulfate (1:1), SY070710, Thieno(3,2-c)pyridine-5(4H)-acetic acid, 6,7-dihydro-alpha-(2-chlorophenyl)-, methyl ester, (S)-, sulfate, Thieno(3,2-c)pyridine-5(4H)-acetic acid, alpha-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (alphaS)-, sulfate (1:1), Clopidogrel (hydrogen sulfate) (Standard), CLOPIDOGREL BISULFATE [ORANGE BOOK], DB-224817, C2556, CLOPIDOGREL BISULFATE [USP MONOGRAPH], SW219457-1, CLOPIDOGREL HYDROGEN SULFATE [EMA EPAR], D00769, EN300-122370, CLOPIDOGREL HYDROGEN SULPHATE [EMA EPAR], CLOPIDOGREL HYDROGEN SULFATE [EP MONOGRAPH], F092016, SR-05000002068, SR-05000002068-1, (S)-(+)-Clopidogrel hydrogensulfate, >=98% (HPLC), Q27888063, S-(+)-Clopidogrel hydrogen sulfate - Bio-X trade mark, Z1541759896, (S)-(+)-Clopidogrel bisulfate, (S)-(+)-Clopidogrel hydrogen sulfate, Clopidogrel bisulfate, United States Pharmacopeia (USP) Reference Standard, Clopidogrel hydrogen sulfate, European Pharmacopoeia (EP) Reference Standard, (S)-(+)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno(3,2-c)pyrid-5-yl)acetate bisulfate, Clopidogrel Bisulfate, Pharmaceutical Secondary Standard, Certified Reference Material, Clopidogrel for system suitability, European Pharmacopoeia (EP) Reference Standard, methyl(S)-2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetatesulfate, (S)-(+)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate hydrogen sulfate, (S)-(2-Chloro-phenyl)-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)-acetic acid methyl ester sulfuric acid salt, (S)-METHYL-(2-CHLORO-PHENYL)-(6,7-DIHYDRO-4H-THIENO[3,2-C]PYRIDIN-5-YL)-ACETATE H2SO4, 120202-48-4, METHYL (+)-(S)-.ALPHA.-(O-CHLOROPHENYL)-6,7-DIHYDROTHIENO(3,2-C)PYRIDINE-5(4H)-ACETATE, SULFATE (1:1), METHYL (+)-(S)-.ALPHA.-(O-CHLOROPHENYL)-6,7-DIHYDROTHIENO(3,2-C)PYRIDINE-5(4H)-ACETATE, SULPHATE (1:1), methyl (2S)-2-(2-chlorophenyl)-2-{4H,5H,6H,7H-thieno[3,2-c]pyridin-5-yl}acetate, sulfuric acid, Methyl (S)-(+)-2-(2-Chlorophenyl)-2-[6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl]acetate Sulfate, Sulfuric acid--methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate (1/1), THIENO(3,2-C)PYRIDINE-5(4H)-ACETIC ACID, .ALPHA.-(2-CHLOROPHENYL)-6,7-DIHYDRO-, METHYL ESTER, (S)-, SULFATE (1:1), THIENO(3,2-C)PYRIDINE-5(4H)-ACETIC ACID, .ALPHA.-(2-CHLOROPHENYL)-6,7-DIHYDRO-, METHYL ESTER, (S)-, SULPHATE (1:1)

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
1-Butanol	273.15	-	247.1	[451]
1-Butanol	278.15	-	276.1	[451]
1-Butanol	283.15	-	324.4	[451]
1-Butanol	288.15	-	339.5	[451]
1-Butanol	293.15	-	383.2	[451]
1-Butanol	298.15	-	396.9	[451]
1-Butanol	303.15	-	432.7	[451]
1-Butanol	308.15	-	476.0	[451]
2-Butanol	273.15	-	17.66	[451]
2-Butanol	278.15	-	24.64	[451]
2-Butanol	283.15	-	31.55	[451]
2-Butanol	288.15	-	44.53	[451]
2-Butanol	293.15	-	58.83	[451]
2-Butanol	298.15	-	73.96	[451]
2-Butanol	303.15	-	88.08	[451]
2-Butanol	308.15	-	109.9	[451]
Acetone	273.15	-	112.8	[451]
Acetone	278.15	-	156.9	[451]
Acetone	283.15	-	203.7	[451]
Acetone	288.15	-	262.6	[451]
Acetone	293.15	-	284.2	[451]
Acetone	298.15	-	341.1	[451]
Acetone	303.15	-	405.5	[451]
Acetone	308.15	-	460.1	[451]
Ethyl acetate	273.15	-	1.226	[451]
Ethyl acetate	278.15	-	1.423	[451]
Ethyl acetate	283.15	-	1.488	[451]
Ethyl acetate	288.15	-	1.733	[451]
Ethyl acetate	293.15	-	1.962	[451]
Ethyl acetate	298.15	-	2.179	[451]
Ethyl acetate	303.15	-	2.3	[451]
Ethyl acetate	308.15	-	2.604	[451]
Isopropanol	273.15	-	46.09	[451]
Isopropanol	278.15	-	63.71	[451]
Isopropanol	283.15	-	74.19	[451]
Isopropanol	288.15	-	111.6	[451]
Isopropanol	293.15	-	133.4	[451]
Isopropanol	298.15	-	171.9	[451]
Isopropanol	303.15	-	215.4	[451]
Isopropanol	308.15	-	262.1	[451]
Methyl acetate	273.15	-	5.223	[451]
Methyl acetate	278.15	-	5.559	[451]
Methyl acetate	283.15	-	6.013	[451]
Methyl acetate	288.15	-	6.53	[451]
Methyl acetate	293.15	-	7.069	[451]
Methyl acetate	298.15	-	7.935	[451]
Methyl acetate	303.15	-	9.823	[451]
Methyl acetate	308.15	-	11.12	[451]
tert-Butyl methyl ether	273.15	-	0.225	[451]
tert-Butyl methyl ether	278.15	-	0.234	[451]
tert-Butyl methyl ether	283.15	-	0.268	[451]
tert-Butyl methyl ether	288.15	-	0.306	[451]
tert-Butyl methyl ether	293.15	-	0.3568	[451]
tert-Butyl methyl ether	298.15	-	0.386	[451]
tert-Butyl methyl ether	303.15	-	0.4243	[451]
tert-Butyl methyl ether	308.15	-	0.4316	[451]

Molecule 3D descriptors

Descriptor	Value
PMI1	1278.2041
PMI2	3137.7989
PMI3	3584.8440
NPR1	0.3566
NPR2	0.8753
RadiusOfGyration	3.0866
InertialShapeFactor	0.0007
Eccentricity	0.9343
Asphericity	0.2805
SpherocityIndex	0.2919
PBF	0.8525