Imatinib

Compound Structure

CAS Number: 152459-95-5

Molecular Mass: 493.6 g/mol

Formula: C29H31N7O

Smiles: Cc1ccc(NC(=O)c2ccc(CN3CCN(C)CC3)cc2)cc1Nc1nccc(-c2cccnc2)n1

Synonymes:

Bioactivity: -

Solubility in Different Solvents

Solvent Temperature [K] Crystal form Solubility [mg/mL] Reference
1-Propanol 273.15 - 2.992 [481]
1-Propanol 278.15 - 3.373 [481]
1-Propanol 283.15 - 3.863 [481]
1-Propanol 288.15 - 4.46 [481]
1-Propanol 293.15 - 5.119 [481]
1-Propanol 298.15 - 5.9 [481]
1-Propanol 303.15 - 6.804 [481]
1-Propanol 308.15 - 7.7 [481]
1-Propanol 313.15 - 8.639 [481]
Acetone 273.15 - 2.296 [481]
Acetone 278.15 - 2.547 [481]
Acetone 283.15 - 2.898 [481]
Acetone 288.15 - 3.271 [481]
Acetone 293.15 - 3.76 [481]
Acetone 298.15 - 4.292 [481]
Acetone 303.15 - 4.929 [481]
Acetone 308.15 - 5.572 [481]
Acetone 313.15 - 6.229 [481]
Acetonitrile 273.15 - 0.097 [481]
Acetonitrile 278.15 - 0.1371 [481]
Acetonitrile 283.15 - 0.1879 [481]
Acetonitrile 288.15 - 0.2568 [481]
Acetonitrile 293.15 - 0.3376 [481]
Acetonitrile 298.15 - 0.4506 [481]
Acetonitrile 303.15 - 0.5816 [481]
Acetonitrile 308.15 - 0.7313 [481]
Acetonitrile 313.15 - 0.8906 [481]
Ethyl acetate 273.15 - 0.446 [481]
Ethyl acetate 278.15 - 0.5918 [481]
Ethyl acetate 283.15 - 0.7263 [481]
Ethyl acetate 288.15 - 0.8787 [481]
Ethyl acetate 293.15 - 1.029 [481]
Ethyl acetate 298.15 - 1.198 [481]
Ethyl acetate 303.15 - 1.409 [481]
Ethyl acetate 308.15 - 1.646 [481]
Ethyl acetate 313.15 - 1.91 [481]
Toluene 273.15 - 3.903 [481]
Toluene 278.15 - 4.44 [481]
Toluene 283.15 - 5.103 [481]
Toluene 288.15 - 5.796 [481]
Toluene 293.15 - 6.585 [481]
Toluene 298.15 - 7.416 [481]
Toluene 303.15 - 8.289 [481]
Toluene 308.15 - 9.124 [481]
Toluene 313.15 - 10.04 [481]

Molecule 3D descriptors

Descriptor Value
PMI1 3750.3074
PMI2 16428.9143
PMI3 19714.8759
NPR1 0.1902
NPR2 0.8333
RadiusOfGyration 6.3569
InertialShapeFactor 0.0002
Eccentricity 0.9817
Asphericity 0.5358
SpherocityIndex 0.0606
PBF 0.7327