Tolfenamic acid

CAS Number: 13710-19-5

Molecular Mass: 261.7 g/mol

Formula: C₁₄H₁₂ClNO₂

Smiles: Cc1c(Cl)cccc1Nc1ccccc1C(=O)O

Synonymes:

Tolfenamic acid, tolfenamic acid, 13710-19-5, Clotam, 2-[(3-Chloro-2-methylphenyl)amino]benzoic Acid, 2-((3-Chloro-2-methylphenyl)amino)benzoic acid, Acido tolfenamico, Acide tolfenamique, N-(3-Chloro-2-methylphenyl)anthranilic acid, Acidum tolfenamicum, N-(3-Chloro-o-tolyl)anthranilic acid, N-(2-Methyl-3-chlorophenyl)anthranilic acid, N-(3-Chloro-o-tolyl)-anthranilic acid, NSC-757873, DTXSID1045409, N-(3-chloro-o-tolyl)anthranilic, 3G943U18KM, DTXCID9025409, CHEBI:32243, 2-([3-Chloro-2-methylphenyl]amino)benzoic acid, Clotam rapid, RefChem:933170, M01AG02, 237-264-3, GEA 6414, 2-(3-Chloro-2-methylanilino)benzoic acid, Tolfedine, Benzoic acid, 2-[(3-chloro-2-methylphenyl)amino]-, MFCD00133865, N-(3-Chloro-ortho-tolyl) anthranilic acid, Anthranilic acid, N-(3-chloro-o-tolyl)-, NCGC00016705-05, Bifenac, CAS-13710-19-5, Benzoic acid, 2-((3-chloro-2-methylphenyl)amino)-, Tolfine, SR-01000000102, Tolfenamic, tolfenamic-acid, UNII-3G943U18KM, Acide tolfenamique [INN-French], Acido tolfenamico [INN-Spanish], Acidum tolfenamicum [INN-Latin], Tolfenamic acid [INN:BAN:JAN], Tolfenamic acid, 2-[(3-Chloro-2-methylphenyl)amino]benzoic acid, N-(3-Chlor-o-tolyl)-anthranilsaure, Prestwick_579, EINECS 237-264-3, Clotam (TN), Tolfenamic acid CRS, BRN 0657821, Spectrum_001263, Tolfenamic acid, NSAID, Prestwick0_000205, Prestwick1_000205, Prestwick2_000205, Prestwick3_000205, Spectrum2_001446, Spectrum3_001762, Spectrum4_000238, Spectrum5_001143, Tolfenamic Acid (Standard), Oprea1_692996, SCHEMBL25190, Tolfenamic acid (JAN/INN), BSPBio_000189, BSPBio_003223, KBioGR_000935, KBioSS_001743, TOLFENAMIC ACID [MI], MLS000028531, BIDD:GT0343, SPECTRUM1501198, TOLFENAMIC ACID [INN], TOLFENAMIC ACID [JAN], SPBio_001311, SPBio_002110, BPBio1_000209, CHEMBL121626, cid_610479, GTPL8769, orb1310296, orb3025021, SCHEMBL29389998, SCHEMBL29484181, TOLFENAMIC ACID [MART.], BDBM35905, HY-B0335R, KBio2_001743, KBio2_004311, KBio2_006879, KBio3_002723, MSK7154, TOLFENAMIC ACID [WHO-DD], HMS1568J11, HMS1921P13, HMS2090D04, HMS2095J11, HMS2230J13, HMS3370A02, HMS3651E06, HMS3712J11, HMS3884M16, HMS5080D09, Pharmakon1600-01501198, HY-B0335, Tox21_110570, CCG-39189, EBC-26362, MSK7154-100M, NSC757873, s1959, SBB058187, TOLFENAMIC ACID [EP IMPURITY], AKOS012836098, TOLFENAMIC ACID [EP MONOGRAPH], Tox21_110570_1, 2-(3-Chloro-o-toluidino)benzoic Acid, DB09216, FT28306, NSC 757873, NCGC00016705-01, NCGC00016705-02, NCGC00016705-03, NCGC00016705-04, NCGC00016705-06, NCGC00016705-07, NCGC00016705-10, NCGC00022587-03, NCGC00022587-04, NCGC00022587-05, AS-13748, DA-11289, n-(3-chloro-ortho-tolyl)anthranilic acid, SMR000058289, SY052546, SBI-0051687.P002, 2-(3-chloro-2-methyl-anilino)benzoic acid, 2-(3-Chloro-2-methylanilino)benzoic acid #, AB00052244, C2064, NS00002545, ST51015128, SW196753-3, UNM000001237003, 2-((3-Chloro-2-methylphenyl)amino)benzoicacid, D01183, D78227, Q59412, AB00052244-15, AB00052244_16, AB00052244_17, EN300-7416304, Tolfenamic acid 1000 microg/mL in Acetonitrile, Tolfenamic acid Solution in Methanol, 100ug/mL, Benzoic acid, 2-(3-chloro-2-methylphenylamino)-, F519604, SR-01000000102-2, SR-01000000102-3, Tolfenamic acid, VETRANAL(TM), analytical standard, BRD-K50133271-001-05-4, BRD-K50133271-001-10-4, BRD-K50133271-001-17-9, BRD-K50133271-001-18-7, Tolfenamic acid, European Pharmacopoeia (EP) Reference Standard, Clotam, Tolfedine,2-[(3-Chloro-2-methylphenyl)amino]benzoic Acid, Tolfenamic Acid, Pharmaceutical Secondary Standard, Certified Reference Material

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
1,4-Dioxane	288.15	-	91.84	[483]
1,4-Dioxane	293.15	-	101.6	[483]
1,4-Dioxane	298.15	-	112.8	[483]
1,4-Dioxane	303.15	-	126.3	[483]
1,4-Dioxane	308.15	-	140.3	[483]
1,4-Dioxane	313.15	-	155.4	[483]
1,4-Dioxane	318.15	-	173.1	[483]
1,4-Dioxane	323.15	-	189.0	[483]
1,4-Dioxane	328.15	-	206.5	[483]
1-Hexanol	283.15	-	9.243	[483]
1-Hexanol	288.15	-	12.31	[483]
1-Hexanol	293.15	-	16.01	[483]
1-Hexanol	298.15	-	19.82	[483]
1-Hexanol	303.15	-	24.74	[483]
1-Hexanol	308.15	-	30.3	[483]
1-Hexanol	313.15	-	36.98	[483]
1-Hexanol	318.15	-	44.08	[483]
1-Hexanol	323.15	-	52.5	[483]
1-Hexanol	328.15	-	61.68	[483]
1-Pentanol	283.15	-	8.193	[483]
1-Pentanol	288.15	-	10.55	[483]
1-Pentanol	293.15	-	14.0	[483]
1-Pentanol	298.15	-	17.97	[483]
1-Pentanol	303.15	-	22.16	[483]
1-Pentanol	308.15	-	27.1	[483]
1-Pentanol	313.15	-	33.21	[483]
1-Pentanol	318.15	-	40.71	[483]
1-Pentanol	323.15	-	49.42	[483]
1-Pentanol	328.15	-	58.38	[483]
Acetonitrile	283.15	-	1.152	[483]
Acetonitrile	288.15	-	1.704	[483]
Acetonitrile	293.15	-	2.312	[483]
Acetonitrile	298.15	-	3.064	[483]
Acetonitrile	303.15	-	3.977	[483]
Acetonitrile	308.15	-	5.249	[483]
Acetonitrile	313.15	-	6.67	[483]
Acetonitrile	318.15	-	8.555	[483]
Acetonitrile	323.15	-	10.58	[483]
Acetonitrile	328.15	-	13.41	[483]
Amyl Acetate	283.15	-	10.02	[483]
Amyl Acetate	288.15	-	12.99	[483]
Amyl Acetate	293.15	-	16.58	[483]
Amyl Acetate	298.15	-	20.6	[483]
Amyl Acetate	303.15	-	25.85	[483]
Amyl Acetate	308.15	-	31.48	[483]
Amyl Acetate	313.15	-	38.29	[483]
Amyl Acetate	318.15	-	45.83	[483]
Amyl Acetate	323.15	-	54.35	[483]
Amyl Acetate	328.15	-	64.91	[483]
Cyclohexane	283.15	-	0.0728	[483]
Cyclohexane	288.15	-	0.1049	[483]
Cyclohexane	293.15	-	0.1438	[483]
Cyclohexane	298.15	-	0.1982	[483]
Cyclohexane	303.15	-	0.2787	[483]
Cyclohexane	308.15	-	0.3785	[483]
Cyclohexane	313.15	-	0.5106	[483]
Cyclohexane	318.15	-	0.6865	[483]
Cyclohexane	323.15	-	0.9132	[483]
Cyclohexane	328.15	-	1.194	[483]
Dimethyl sulfoxide	293.15	-	53.78	[483]
Dimethyl sulfoxide	298.15	-	69.62	[483]
Dimethyl sulfoxide	303.15	-	85.76	[483]
Dimethyl sulfoxide	308.15	-	107.8	[483]
Dimethyl sulfoxide	313.15	-	131.6	[483]
Dimethyl sulfoxide	318.15	-	158.1	[483]
Dimethyl sulfoxide	323.15	-	186.9	[483]
Dimethyl sulfoxide	328.15	-	216.3	[483]
Dimethylformamide	283.15	-	22.54	[483]
Dimethylformamide	288.15	-	30.74	[483]
Dimethylformamide	293.15	-	40.22	[483]
Dimethylformamide	298.15	-	52.12	[483]
Dimethylformamide	303.15	-	65.1	[483]
Dimethylformamide	308.15	-	82.47	[483]
Dimethylformamide	313.15	-	104.1	[483]
Dimethylformamide	318.15	-	128.5	[483]
Dimethylformamide	323.15	-	156.8	[483]
Dimethylformamide	328.15	-	190.7	[483]
Ethyl acetate	283.15	-	16.44	[483]
Ethyl acetate	288.15	-	21.7	[483]
Ethyl acetate	293.15	-	27.67	[483]
Ethyl acetate	298.15	-	34.31	[483]
Ethyl acetate	303.15	-	43.51	[483]
Ethyl acetate	308.15	-	53.75	[483]
Ethyl acetate	313.15	-	67.23	[483]
Ethyl acetate	318.15	-	83.87	[483]
Ethyl acetate	323.15	-	102.1	[483]
Ethyl acetate	328.15	-	122.3	[483]
Ethyl formate	283.15	-	5.59	[483]
Ethyl formate	288.15	-	7.861	[483]
Ethyl formate	293.15	-	10.14	[483]
Ethyl formate	298.15	-	13.16	[483]
Ethyl formate	303.15	-	16.3	[483]
Ethyl formate	308.15	-	21.17	[483]
Ethyl formate	313.15	-	26.54	[483]
Ethyl formate	318.15	-	31.8	[483]
Ethyl formate	323.15	-	41.29	[483]
Ethyl formate	328.15	-	50.07	[483]
Ethylene Glycol	283.15	-	0.4129	[483]
Ethylene Glycol	288.15	-	0.6221	[483]
Ethylene Glycol	293.15	-	0.8296	[483]
Ethylene Glycol	298.15	-	1.091	[483]
Ethylene Glycol	303.15	-	1.452	[483]
Ethylene Glycol	308.15	-	1.889	[483]
Ethylene Glycol	313.15	-	2.534	[483]
Ethylene Glycol	318.15	-	3.315	[483]
Ethylene Glycol	323.15	-	4.288	[483]
Ethylene Glycol	328.15	-	5.609	[483]
Heptanol	283.15	-	10.47	[483]
Heptanol	288.15	-	13.6	[483]
Heptanol	293.15	-	17.27	[483]
Heptanol	298.15	-	21.34	[483]
Heptanol	303.15	-	26.51	[483]
Heptanol	308.15	-	31.88	[483]
Heptanol	313.15	-	39.88	[483]
Heptanol	318.15	-	47.81	[483]
Heptanol	323.15	-	56.73	[483]
Heptanol	328.15	-	68.16	[483]

Molecule 3D descriptors

Descriptor	Value
PMI1	662.9278
PMI2	2582.2564
PMI3	2969.6896
NPR1	0.2232
NPR2	0.8695
RadiusOfGyration	3.4458
InertialShapeFactor	0.0013
Eccentricity	0.9748
Asphericity	0.4741
SpherocityIndex	0.2361
PBF	0.8206