Lenalidomide

CAS Number: 191732-72-6

Molecular Mass: 259.26 g/mol

Formula: C₁₃H₁₃N₃O₃

Smiles: Nc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O

Synonymes:

Lenalidomide, 191732-72-6, Revlimid, Revimid, 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione, CC-5013, 2,6-Piperidinedione, 3-(4-amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-, CDC 501, CDC-501, 3-(4-Amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione, Lenalidomida, DTXSID8046664, NSC-747972, F0P408N6V4, 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline, SYP-1512, 3-(4-amino-1-oxo-2,3-dihydro-1H-isoindol-2-yl)piperidine-2,6-dione, DTXCID6026664, CHEBI:63791, 4-amino-2-(6-hydroxy-2-oxo-2,3,4,5-tetrahydropyridin-3-yl)-2,3-dihydro-1H-isoindol-1-one, CC5013, IMiD3 cpd, lenalidomidum, RefChem:5941, L04AX04, NSC703813, 691-297-1, Lenalidomide (CC-5013), MFCD07772307, 3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione, CC 5013, Lenadoamide, C13H13N3O3, Revlimid (TN), 3-(4-amino-1,3-dihydro-1-oxo-2h-isoindol-2-yl)-2,6-piperidinedione, s1029, NCGC00167491-01, Lenalidomide [USAN], 3-(4-Amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione, CAS-191732-72-6, Lenalidomide?, UNII-F0P408N6V4, Lenalidomide [USAN:INN:BAN], Revimid, , ENMD 0997, ENMD-0997, HSDB 8220, IMID-5013, CDC-5013, ALBB-015321, Lenalidomide (Standard), LENALIDOMIDE [MI], LENALIDOMIDE [INN], LENALIDOMIDE [JAN], CHEMBL848, Revlimid (TN) (Celgene), LENALIDOMIDE [VANDF], SCHEMBL32978, LENALIDOMIDE [MART.], MLS003899194, LENALIDOMIDE [WHO-DD], GTPL7331, Lenalidomide (JAN/USAN/INN), orb1307920, LENALIDOMIDE [EMA EPAR], 3-(4-amino-1-oxo-isoindolin-2-yl)piperidine-2,6-dione, SCHEMBL26646478, SCHEMBL29414335, BDBM65454, HY-A0003R, Lenalidomide - Bio-X trade mark, 3-(7-Amino-3-oxo-1H-isoindol-2-yl)-piperidine-2,6-dione, HMS3654G07, HMS3674C05, HMS5079I05, LENALIDOMIDE [ORANGE BOOK], CIA27191, HY-A0003, MSK10368, Revlimid, Lenalidomide, CC-5013, Tox21_112492, AC-914, EBC-11297, NSC747972, STK639603, 2,6-Piperidinedione, 3-(4-amino-1,3-dihydro-1-oxo-2H- isoindol-2-yl)-, AKOS005146276, AKOS005174869, Tox21_112492_1, CCG-264781, CS-0125, DB00480, FL24864, KS-1207, NSC 747972, SB66166, NCGC00167491-02, NCGC00167491-03, NCGC00167491-04, NCGC01443006-01, BL164614, BP-27972, SMR002529986, SY047646, NS00003666, SW218084-2, D04687, EN300-118706, AB01273975-01, AB01273975-02, AB01273975_03, F078933, Q425681, SR-01000883999, SR-01000883999-1, 1-Oxo-4-amino-2-(2,6-dioxopiperidin-3-yl)isoindole, BRD-A17883755-001-06-1, 3-(4-Amino-1-oxo-2-isoindolinyl)piperidine-2,6-dione, Z1515385074, 2, 3-(4-amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-, 3-(4-amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)-2,6-dioxopiperidine

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
Acetonitrile	273.15	-	2.256	[106]
Acetonitrile	278.15	-	2.312	[106]
Acetonitrile	283.15	-	2.386	[106]
Acetonitrile	288.15	-	2.469	[106]
Acetonitrile	293.15	-	2.664	[105]
Acetonitrile	293.15	-	2.551	[106]
Acetonitrile	298.15	-	2.694	[105]
Acetonitrile	298.15	-	2.631	[106]
Acetonitrile	303.15	-	2.732	[105]
Acetonitrile	303.15	-	2.72	[106]
Acetonitrile	308.15	-	2.775	[105]
Acetonitrile	308.15	-	2.802	[106]
Acetonitrile	313.15	-	2.824	[105]
Acetonitrile	313.15	-	2.888	[106]
Acetonitrile	318.15	-	2.875	[105]
Acetonitrile	318.15	-	2.971	[106]
Acetonitrile	323.15	-	2.926	[105]
Acetonitrile	328.15	-	2.982	[105]
Acetonitrile	333.15	-	3.042	[105]
Ethanol	293.15	-	0.7302	[105]
Ethanol	298.15	-	0.8082	[105]
Ethanol	303.15	-	0.9173	[105]
Ethanol	308.15	-	1.042	[105]
Ethanol	313.15	-	1.175	[105]
Ethanol	318.15	-	1.334	[105]
Ethanol	323.15	-	1.534	[105]
Ethanol	328.15	-	1.724	[105]
Ethanol	333.15	-	1.952	[105]
Ethyl acetate	273.15	-	0.22	[106]
Ethyl acetate	278.15	-	0.249	[106]
Ethyl acetate	283.15	-	0.2821	[106]
Ethyl acetate	288.15	-	0.32	[106]
Ethyl acetate	293.15	-	0.3371	[105]
Ethyl acetate	293.15	-	0.3604	[106]
Ethyl acetate	298.15	-	0.3788	[105]
Ethyl acetate	298.15	-	0.4001	[106]
Ethyl acetate	303.15	-	0.4285	[105]
Ethyl acetate	303.15	-	0.4392	[106]
Ethyl acetate	308.15	-	0.4775	[105]
Ethyl acetate	308.15	-	0.4829	[106]
Ethyl acetate	313.15	-	0.5416	[105]
Ethyl acetate	313.15	-	0.531	[106]
Ethyl acetate	318.15	-	0.6114	[105]
Ethyl acetate	318.15	-	0.5784	[106]
Ethyl acetate	323.15	-	0.7034	[105]
Ethyl acetate	328.15	-	0.8041	[105]
Ethyl acetate	333.15	-	0.9198	[105]
Isopropanol	273.15	-	0.0866	[106]
Isopropanol	278.15	-	0.11	[106]
Isopropanol	283.15	-	0.141	[106]
Isopropanol	288.15	-	0.177	[106]
Isopropanol	293.15	-	0.2159	[105]
Isopropanol	293.15	-	0.224	[106]
Isopropanol	298.15	-	0.2625	[105]
Isopropanol	298.15	-	0.27	[106]
Isopropanol	303.15	-	0.318	[105]
Isopropanol	303.15	-	0.318	[106]
Isopropanol	308.15	-	0.3868	[105]
Isopropanol	308.15	-	0.3801	[106]
Isopropanol	313.15	-	0.469	[105]
Isopropanol	313.15	-	0.4507	[106]
Isopropanol	318.15	-	0.5533	[105]
Isopropanol	318.15	-	0.527	[106]
Isopropanol	323.15	-	0.6395	[105]
Isopropanol	328.15	-	0.7526	[105]
Isopropanol	333.15	-	0.8775	[105]
Methanol	273.15	-	1.25	[106]
Methanol	278.15	-	1.329	[106]
Methanol	283.15	-	1.43	[106]
Methanol	288.15	-	1.526	[106]
Methanol	293.15	-	1.616	[105]
Methanol	293.15	-	1.639	[106]
Methanol	298.15	-	1.712	[105]
Methanol	298.15	-	1.757	[106]
Methanol	303.15	-	1.822	[105]
Methanol	303.15	-	1.904	[106]
Methanol	308.15	-	1.943	[105]
Methanol	308.15	-	2.05	[106]
Methanol	313.15	-	2.074	[105]
Methanol	313.15	-	2.194	[106]
Methanol	318.15	-	2.229	[105]
Methanol	318.15	-	2.379	[106]
Methanol	323.15	-	2.433	[105]
Methanol	328.15	-	2.661	[105]
Methanol	333.15	-	2.93	[105]

Molecule 3D descriptors

Descriptor	Value
PMI1	491.0998
PMI2	2553.3988
PMI3	2733.7334
NPR1	0.1796
NPR2	0.9340
RadiusOfGyration	3.3382
InertialShapeFactor	0.0019
Eccentricity	0.9837
Asphericity	0.5580
SpherocityIndex	0.2022
PBF	0.6719