Bezafibrate

CAS Number: 41859-67-0

Molecular Mass: 361.8 g/mol

Formula: C₁₉H₂₀ClNO₄

Smiles: CC(C)(Oc1ccc(CCNC(=O)c2ccc(Cl)cc2)cc1)C(=O)O

Synonymes:

Bezafibrate, bezafibrate, 41859-67-0, Bezalip, Bezafibrato, Bezatol SR, Bezafibratum, BM-15.075, BM-15075, BM 15.075, DTXSID3029869, NSC-758174, Y9449Q51XH, Propanoic acid, 2-(4-(2-((4-chlorobenzoyl)amino)ethyl)phenoxy)-2-methyl-, DTXCID909869, CHEBI:47612, Propanoic acid, 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methyl-, Beza Lande, Beza Puren, BM15.075, Bezalip-mono, Fibrazate xl, Zimbacol xl, Bezagen xl, Liparol xl, RefChem:58600, C10AB02, 255-567-9, Cedur, Befizal, Bezafibrat, Sklerofibrat, Azufibrat, Bezafibratum [INN-Latin], Bezafibrato [INN-Spanish], Bezatol SR (TN), 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methylpropanoic acid, 2-(4-(2-(4-Chlorobenzamido)ethyl)phenoxy)-2-methylpropanoic acid, 2-(p-(2-(p-Chlorobenzamido)ethyl)phenoxy)-2-methylpropionic acid, MFCD00078970, Difaterol, Bezatol, 2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]-2-methylpropanoic acid, 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methyl-propanoic acid, MLS000028533, CHEMBL264374, durabezur, Reducterol, Bezabeta, Bezacur, Bezamerck, Eulitop, Solibay, Lipox, Bezafibrat PB, Beza-Lande, Beza-Puren, Regadrin B, 2-(4-{2-[(4-chlorophenyl)formamido]ethyl}phenoxy)-2-methylpropanoic acid, BM15075, NCGC00016850-01, SMR000058298, Bezafibrato [Spanish], Bezalip Retard, CAS-41859-67-0, BF-759, 2-{4-[2-(4-chlorobenzamido)ethyl]phenoxy}-2-methylpropanoic acid, BM 15075, LO 44, 2-(4-{2-[(4-chlorobenzoyl)amino]ethyl}phenoxy)-2-methylpropanoic acid, 2-[P-[2-P-CHLOROBENZAMIDO)ETHYL]PHENOXY]-2-METHYLPROPIONIC ACID, CCRIS 9085, SR-01000000106, EINECS 255-567-9, BRN 4267656, UNII-Y9449Q51XH, Bezafibrate CRS, Bezalip SR, Bezafibrate [USAN:INN:BAN:JAN], PEM, Prestwick_724, BENAFIBRATE, a-[4-(4-chlorobenzoylaminoethyl)phenoxy]isobutyric acid, Bezafibrate (Standard), Spectrum_001443, Opera_ID_376, BEZAFIBRATE [MI], Prestwick0_000378, Prestwick1_000378, Prestwick2_000378, Prestwick3_000378, Spectrum2_000922, Spectrum3_001500, Spectrum4_000325, Spectrum5_001079, Spectrum5_001967, BEZAFIBRATE [INN], BEZAFIBRATE [JAN], BEZAFIBRATE [USAN], BEZAFIBRATE [MART.], SCHEMBL16299, BEZAFIBRATE [WHO-DD], BSPBio_000535, BSPBio_001314, BSPBio_003119, KBioGR_000034, KBioGR_000669, KBioSS_000034, KBioSS_001923, MLS001148205, Bezafibrate, >=98%, solid, DivK1c_000092, SPECTRUM1502046, SPBio_000824, SPBio_002456, BPBio1_000589, GTPL2668, orb1310243, orb3025853, Bezafibrate - Bio-X trade mark, BDBM28701, Bezafibrate (JP18/USAN/INN), HMS500E14, HY-B0637R, KBio1_000092, KBio2_000034, KBio2_001923, KBio2_002602, KBio2_004491, KBio2_005170, KBio2_007059, KBio3_000067, KBio3_000068, KBio3_002619, 2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]isobutyric Acid, NINDS_000092, BEZAFIBRATE [EP MONOGRAPH], Bio2_000034, Bio2_000514, HMS1361B16, HMS1569K17, HMS1791B16, HMS1921H16, HMS1989B16, HMS2089F04, HMS2092B12, HMS2096K17, HMS2233E22, HMS3261D21, HMS3369B13, HMS3402B16, HMS3650K22, HMS3652M22, HMS3713K17, HMS5082C22, Pharmakon1600-01502046, HY-B0637, MSK10345, UYB80274, Tox21_110645, Tox21_301845, Tox21_500500, CCG-39683, EBC-26794, NSC758174, s4159, AKOS005107743, Propionic acid, 2-(4-(2-((4-chlorobenzoyl)amino)ethyl)phenoxy)-2-methyl-, Tox21_110645_1, AB03023, AC-6817, DB01393, FB18580, HS-0040, LP00500, NSC 758174, SB17361, SDCCGSBI-0051715.P003, IDI1_000092, IDI1_033784, NCGC00016850-02, NCGC00016850-03, NCGC00016850-04, NCGC00016850-05, NCGC00016850-06, NCGC00016850-07, NCGC00016850-08, NCGC00016850-09, NCGC00016850-10, NCGC00016850-11, NCGC00016850-12, NCGC00016850-15, NCGC00016850-25, NCGC00023317-03, NCGC00023317-04, NCGC00023317-05, NCGC00023317-06, NCGC00023317-07, NCGC00023317-08, NCGC00255376-01, NCGC00261185-01, BB166159, Bezafibrate, analytical reference material, SY052507, Bezafibrate 100 microg/mL in Acetonitrile, SBI-0051715.P002, DB-238976, AB00052265, B3346, NS00000219, ST51014927, SW196871-4, D01366, D70191, AB00052265-15, AB00052265_16, AB00052265_17, EN300-18539646, F544300, Q577387, SR-01000000106-3, SR-01000000106-4, SR-01000000106-5, BRD-K46018455-001-06-0, BRD-K46018455-001-17-7, BRD-K46018455-001-26-8, BRD-K46018455-001-27-6, SR-01000000106-10, Bezafibrate Working Standard (Secondary Reference Standard), Bezafibrate, European Pharmacopoeia (EP) Reference Standard, 2-(4-(2-parachlorobenzamidoethyl)phenoxy)-2-methylpropionic acid, 2-[4-[2-(4-chlorobezamide)ethyl]phenoxy]-2-methylpropanoic acid, 2-[4-[2-[(4-Chlorobenzoyl)amino]ethyl]phenoxyl]-2-methylpropanoic Acid, 2-(4-{2-[(4-chlorophenyl)carbonylamino]ethyl}phenoxy)-2-methylpropanoic acid, 2-[4-(2-{[(4-chlorophenyl)carbonyl]amino}ethyl)phenoxy]-2-methylpropanoic acid

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
1-Butanol	283.16	-	9.073	[120]
1-Butanol	288.17	-	10.74	[120]
1-Butanol	293.14	-	13.18	[120]
1-Butanol	298.17	-	15.91	[120]
1-Butanol	303.16	-	19.41	[120]
1-Butanol	308.14	-	23.48	[120]
1-Butanol	313.17	-	28.42	[120]
1-Butanol	318.16	-	34.29	[120]
1-Butanol	323.17	-	40.36	[120]
1-Pentanol	283.23	-	7.879	[120]
1-Pentanol	288.23	-	9.641	[120]
1-Pentanol	293.29	-	11.54	[120]
1-Pentanol	298.5	-	13.63	[120]
1-Pentanol	303.24	-	16.54	[120]
1-Pentanol	308.02	-	19.91	[120]
1-Pentanol	313.08	-	23.82	[120]
1-Pentanol	317.95	-	28.26	[120]
1-Pentanol	322.74	-	33.74	[120]
1-Propanol	283.13	-	11.71	[120]
1-Propanol	283.15	-	12.07	[119]
1-Propanol	288.15	-	14.47	[119]
1-Propanol	288.18	-	14.1	[120]
1-Propanol	293.15	-	17.54	[119]
1-Propanol	293.27	-	17.04	[120]
1-Propanol	298.15	-	21.13	[119]
1-Propanol	298.53	-	20.36	[120]
1-Propanol	303.15	-	25.25	[119]
1-Propanol	303.33	-	24.86	[120]
1-Propanol	308.15	-	30.24	[119]
1-Propanol	308.23	-	29.58	[120]
1-Propanol	313.15	-	35.49	[119]
1-Propanol	313.37	-	34.82	[120]
1-Propanol	318.15	-	41.89	[119]
1-Propanol	318.35	-	40.71	[120]
1-Propanol	323.15	-	48.1	[119]
1-Propanol	323.26	-	49.16	[120]
2-Butanol	283.16	-	9.184	[120]
2-Butanol	288.17	-	11.67	[120]
2-Butanol	293.14	-	14.43	[120]
2-Butanol	298.16	-	17.46	[120]
2-Butanol	303.16	-	20.76	[120]
2-Butanol	308.14	-	25.02	[120]
2-Butanol	313.17	-	29.74	[120]
2-Butanol	318.16	-	35.32	[120]
2-Butanol	323.16	-	40.84	[120]
Acetonitrile	283.24	-	0.7929	[120]
Acetonitrile	288.25	-	1.062	[120]
Acetonitrile	293.24	-	1.395	[120]
Acetonitrile	298.25	-	1.876	[120]
Acetonitrile	303.24	-	2.414	[120]
Acetonitrile	308.22	-	3.172	[120]
Acetonitrile	313.22	-	4.189	[120]
Acetonitrile	318.23	-	5.384	[120]
Acetonitrile	323.24	-	6.792	[120]
Butyl acetate	283.17	-	0.9075	[120]
Butyl acetate	288.19	-	1.106	[120]
Butyl acetate	293.2	-	1.356	[120]
Butyl acetate	298.14	-	1.716	[120]
Butyl acetate	303.19	-	2.116	[120]
Butyl acetate	308.16	-	2.559	[120]
Butyl acetate	313.14	-	3.047	[120]
Butyl acetate	318.14	-	3.696	[120]
Butyl acetate	323.2	-	4.448	[120]
Cyclohexanone	283.14	-	17.58	[120]
Cyclohexanone	288.19	-	21.37	[120]
Cyclohexanone	293.24	-	25.73	[120]
Cyclohexanone	298.14	-	31.23	[120]
Cyclohexanone	303.27	-	37.22	[120]
Cyclohexanone	308.13	-	44.41	[120]
Cyclohexanone	313.19	-	52.69	[120]
Cyclohexanone	318.22	-	61.43	[120]
Cyclohexanone	323.22	-	70.64	[120]
Ethanol	283.14	-	16.23	[120]
Ethanol	283.15	-	13.99	[119]
Ethanol	288.15	-	16.92	[119]
Ethanol	288.24	-	17.6	[120]
Ethanol	293.15	-	20.66	[119]
Ethanol	293.3	-	20.49	[120]
Ethanol	298.15	-	24.88	[119]
Ethanol	298.28	-	24.18	[120]
Ethanol	303.15	-	29.72	[119]
Ethanol	303.24	-	28.65	[120]
Ethanol	308.15	-	35.03	[119]
Ethanol	308.22	-	33.01	[120]
Ethanol	313.13	-	40.54	[120]
Ethanol	313.15	-	42.05	[119]
Ethanol	318.15	-	49.57	[119]
Ethanol	318.18	-	48.75	[120]
Ethanol	323.15	-	59.15	[119]
Ethanol	323.24	-	58.83	[120]
Ethyl acetate	283.17	-	2.09	[120]
Ethyl acetate	288.17	-	2.478	[120]
Ethyl acetate	293.16	-	2.92	[120]
Ethyl acetate	298.14	-	3.654	[120]
Ethyl acetate	303.17	-	4.398	[120]
Ethyl acetate	308.14	-	5.332	[120]
Ethyl acetate	313.17	-	6.406	[120]
Ethyl acetate	318.16	-	7.891	[120]
Ethyl acetate	323.19	-	9.328	[120]
Isoamyl Alcohol	283.77	-	4.992	[120]
Isoamyl Alcohol	288.56	-	6.532	[120]
Isoamyl Alcohol	293.5	-	8.246	[120]
Isoamyl Alcohol	298.59	-	10.06	[120]
Isoamyl Alcohol	303.13	-	12.03	[120]
Isoamyl Alcohol	308.21	-	14.86	[120]
Isoamyl Alcohol	313.25	-	18.16	[120]
Isoamyl Alcohol	318.17	-	21.91	[120]
Isoamyl Alcohol	323.25	-	26.57	[120]
Isobutanol	282.95	-	4.544	[120]
Isobutanol	288.04	-	5.902	[120]
Isobutanol	292.93	-	7.974	[120]
Isobutanol	298.24	-	10.15	[120]
Isobutanol	303.2	-	12.28	[120]
Isobutanol	308.22	-	15.32	[120]
Isobutanol	313.23	-	18.84	[120]
Isobutanol	318.17	-	23.15	[120]
Isobutanol	323.2	-	28.41	[120]
Isopropanol	283.06	-	6.979	[120]
Isopropanol	283.15	-	7.28	[119]
Isopropanol	288.14	-	9.3	[120]
Isopropanol	288.15	-	9.02	[119]
Isopropanol	293.15	-	11.24	[119]
Isopropanol	293.19	-	11.63	[120]
Isopropanol	298.15	-	14.5	[119]
Isopropanol	298.24	-	14.24	[120]
Isopropanol	303.15	-	18.03	[119]
Isopropanol	303.21	-	17.41	[120]
Isopropanol	308.15	-	22.24	[119]
Isopropanol	308.16	-	21.57	[120]
Isopropanol	313.14	-	26.49	[120]
Isopropanol	313.15	-	26.19	[119]
Isopropanol	318.15	-	31.89	[119]
Isopropanol	318.22	-	32.66	[120]
Isopropanol	323.15	-	38.33	[119]
Isopropanol	323.2	-	39.29	[120]
Methanol	283.12	-	21.09	[120]
Methanol	283.15	-	17.19	[119]
Methanol	288.15	-	20.49	[119]
Methanol	288.24	-	22.36	[120]
Methanol	293.15	-	25.36	[119]
Methanol	293.26	-	25.25	[120]
Methanol	298.15	-	30.51	[119]
Methanol	298.17	-	29.69	[120]
Methanol	303.12	-	36.16	[120]
Methanol	303.15	-	38.14	[119]
Methanol	308.14	-	43.88	[120]
Methanol	308.15	-	46.34	[119]
Methanol	313.13	-	53.83	[120]
Methanol	313.15	-	56.86	[119]
Methanol	318.14	-	65.81	[120]
Methanol	318.15	-	69.1	[119]
Methanol	323.12	-	79.69	[120]
Methanol	323.15	-	82.4	[119]
Methyl ethyl ketone	283.14	-	7.832	[120]
Methyl ethyl ketone	288.16	-	9.229	[120]
Methyl ethyl ketone	293.17	-	10.86	[120]
Methyl ethyl ketone	298.16	-	12.57	[120]
Methyl ethyl ketone	303.17	-	14.8	[120]
Methyl ethyl ketone	308.14	-	17.34	[120]
Methyl ethyl ketone	313.16	-	19.97	[120]
Methyl ethyl ketone	318.17	-	22.81	[120]
Methyl ethyl ketone	323.16	-	26.75	[120]
Propyl acetate	283.16	-	1.457	[120]
Propyl acetate	288.24	-	1.737	[120]
Propyl acetate	293.16	-	2.093	[120]
Propyl acetate	298.18	-	2.562	[120]
Propyl acetate	303.16	-	3.11	[120]
Propyl acetate	308.16	-	3.756	[120]
Propyl acetate	313.18	-	4.484	[120]
Propyl acetate	318.16	-	5.41	[120]
Propyl acetate	323.16	-	6.497	[120]
Water	283.15	-	0.0247	[119]
Water	288.15	-	0.0318	[119]
Water	293.15	-	0.0403	[119]
Water	298.15	-	0.0512	[119]
Water	303.15	-	0.0658	[119]
Water	308.15	-	0.0825	[119]
Water	313.15	-	0.1022	[119]
Water	318.15	-	0.1253	[119]
Water	323.15	-	0.1553	[119]

Molecule 3D descriptors

Descriptor	Value
PMI1	630.4278
PMI2	10897.6256
PMI3	10953.6485
NPR1	0.0576
NPR2	0.9949
RadiusOfGyration	5.5738
InertialShapeFactor	0.0016
Eccentricity	0.9983
Asphericity	0.8388
SpherocityIndex	0.0946
PBF	0.7573