Pomalidomide

CAS Number: 19171-19-8

Molecular Mass: 273.24 g/mol

Formula: C₁₃H₁₁N₃O₄

Smiles: Nc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O

Synonymes:

Pomalidomide, 19171-19-8, Actimid, CC-4047, Pomalyst, Imnovid, 4-Aminothalidomide, 4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione, 1H-Isoindole-1,3(2H)-dione, 4-amino-2-(2,6-dioxo-3-piperidinyl)-, 3-Amino-N-(2,6-dioxo-3-piperidyl)phthalimide, IMiD 3, CC 4047, IMID-3, 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione, IMiD3, Pomalidomida, D2UX06XLB5, CC4047, CHEBI:72690, DTXSID40893458, 4-amino-2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione, Phthalimide, 3-amino-N-(2,6-dioxo-3-piperidyl)-, pomalidomidum, RefChem:55885, L04AX06, DTXCID801323473, 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione, MFCD12756407, 4-Amino-2-(2,6-dioxo-3-piperidinyl)isoindole-1,3-dione, s1567, 4-amino-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione, 1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline, S-3APG, Pomalidomide [USAN:INN], UNII-D2UX06XLB5, Pomalidomid, Pomalidomide?, HSDB 8222, Pomalyst (TN), 443919-33-3, IMiD1, Pomalidomide (Standard), 4-amino-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione, POMALIDOMIDE [MI], POMALIDOMIDE [INN], POMALIDOMIDE [JAN], 3-amino-N-(2,6-dioxo-3-piperidyl)phthalamide, POMALIDOMIDE [USAN], 3-Aminophthalimidoglutarimide, POMALIDOMIDE [VANDF], MLS006011261, CHEMBL43452, POMALIDOMIDE [WHO-DD], SCHEMBL369172, GTPL7348, orb1305562, Pomalidomide (JAN/USAN/INN), POMALIDOMIDE [EMA EPAR], 3-aminio-phthalimido-glutarimide, SCHEMBL19250920, BDBM65456, IMID-4047, Pomalidomide - Bio-X trade mark, CDC-394, Pomalidomide, >=98% (HPLC), s-3-amino-phthalimido-glutarimide, UVSMNLNDYGZFPF-UHFFFAOYSA-N, GLXC-06238, HMS3655G05, HMS3744K07, HMS5079E16, POMALIDOMIDE [ORANGE BOOK], EBC-11137, HY-10984R, NSC767909, NSC775351, AKOS013400288, CCG-264684, CS-0165, DB08910, FA30210, NSC-767909, NSC-775351, SB16552, NCGC00346551-01, NCGC00346551-03, NCGC00346551-07, NCGC00346551-09, AC-26970, AS-17905, BP-24477, BP164278, DA-21486, HY-10984, SMR004703012, SY054807, 3-(3-AMINO)-PHTALAMIDO-GLUTARIMIDE, P2074, SW218099-2, D08976, EN300-317097, AB01565777_02, F230365, SR-01000941573, Q7227206, SR-01000941573-1, BRD-A12994259-001-02-1, 4-amino-2-(2,6-dioxo-3-piperidyl)isoindole-1,3-dione, Z1269642575, 2-(2,6-Dioxopiperidin-3-yl)-4-amino-isoindole-1,3-dione, 4-amino-2-(2,6-dioxo(3-piperidyl))isoindoline-1,3-dione, 4-Amino-2-[(3RS)-2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
Acetone	278.15	-	0.0054	[136]
Acetone	283.15	-	0.0075	[136]
Acetone	288.15	-	0.0097	[136]
Acetone	293.15	-	0.01234	[136]
Acetone	298.15	-	0.01577	[136]
Acetone	303.15	-	0.0195	[136]
Acetone	308.15	-	0.02376	[136]
Acetone	313.15	-	0.02831	[136]
Acetone	318.15	-	0.03399	[136]
Ethanol	278.15	-	9.0 × 10⁻⁴	[136]
Ethanol	283.15	-	0.00114	[136]
Ethanol	288.15	-	0.00146	[136]
Ethanol	293.15	-	0.00192	[136]
Ethanol	298.15	-	0.00247	[136]
Ethanol	303.15	-	0.0031	[136]
Ethanol	308.15	-	0.00391	[136]
Ethanol	313.15	-	0.0048	[136]
Ethanol	318.15	-	0.0057	[136]
Ethyl acetate	278.15	-	0.00128	[136]
Ethyl acetate	283.15	-	0.00187	[136]
Ethyl acetate	288.15	-	0.00261	[136]
Ethyl acetate	293.15	-	0.0034	[136]
Ethyl acetate	298.15	-	0.0043	[136]
Ethyl acetate	303.15	-	0.0054	[136]
Ethyl acetate	308.15	-	0.0065	[136]
Ethyl acetate	313.15	-	0.00804	[136]
Ethyl acetate	318.15	-	0.0098	[136]
Isopropanol	278.15	-	8.0 × 10⁻⁴	[136]
Isopropanol	283.15	-	0.0012	[136]
Isopropanol	288.15	-	0.00172	[136]
Isopropanol	293.15	-	0.00225	[136]
Isopropanol	298.15	-	0.00288	[136]
Isopropanol	303.15	-	0.0036	[136]
Isopropanol	308.15	-	0.0044	[136]
Isopropanol	313.15	-	0.0054	[136]
Isopropanol	318.15	-	0.0066	[136]

Molecule 3D descriptors

Descriptor	Value
PMI1	565.4070
PMI2	2563.2448
PMI3	2788.9041
NPR1	0.2027
NPR2	0.9191
RadiusOfGyration	3.2906
InertialShapeFactor	0.0016
Eccentricity	0.9792
Asphericity	0.5132
SpherocityIndex	0.2012
PBF	0.6029