Carvedilol

CAS Number: 72956-09-3

Molecular Mass: 406.5 g/mol

Formula: C₂₄H₂₆N₂O₄

Smiles: COc1ccccc1OCCNCC(O)COc1cccc2[nH]c3ccccc3c12

Synonymes:

Carvedilol, carvedilol, 72956-09-3, Coreg, Dilatrend, Eucardic, Carvedilolum, Artist, Kredex, Dimitone, Querto, BM-14190, Coronis, Korvasan, Talliton, SKF 105517, 1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol, DQ 2466, DQ-2466, SK&F-105517, (+-)-1-(Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol, NSC-758694, SKF-105517, BM 14.190, BM-14-190, BM-14.190, C07AG02, 0K47UL67F2, CHEBI:3441, DTXSID8022747, BM14190, 1-(9H-Carbazol-4-yloxy)-3-(2-(2-methoxyphenoxy)ethylamino)propan-2-ol, [3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-methoxyphenoxy)ethyl]amine, 2-Propanol, 1-(9H-carbazol-4-yloxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)-, (+-)-, 2-Propanol, 1-(9H-carbazol-4-yloxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)-, 2-Propanol, 1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-, carvedilolo, (3-(9H-carbazol-4-yloxy)-2-hydroxypropyl)(2-(2-methoxyphenoxy)ethyl)amine, Eucardic 25, Eucardic 12.5, Eucardic 6.25, Eucardic 3.125, 14C-labeled Carvedilol, RefChem:54726, Carvedilol, 14C labeled, DTXCID602747, (2RS)-1-(9H-Carbazol-4-yloxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)propan-2-ol, 615-871-8, 658-032-1, 1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol, Carvedilolum [Latin], 1-((9H-Carbazol-4-yl)oxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)propan-2-ol, BM 14190, MFCD00864692, CHEMBL723, 1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol, Coropress, Dibloc, SMR000449280, Artist (TN), Coreg (TN), HSDB 7044, SR-01000759289, UNII-0K47UL67F2, Carvedilol CRS, Coreg, , 1-[(9H-Carbazol-4-yl)oxy]-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol, EG-P042, (R)-BM 14190, Carvedilol [USAN:USP:INN:BAN:JAN], Carvedilol (Standard), Spectrum_001665, Carvedilol (R)-Isomer, CARVEDILOL [MI], CARVEDILOL [INN], CARVEDILOL [JAN], Spectrum2_001673, Spectrum3_001182, Spectrum4_000636, Spectrum5_001436, CARVEDILOL [HSDB], CARVEDILOL [USAN], CARVEDILOL [VANDF], CARVEDILOL [MART.], CARVEDILOL [USP-RS], CARVEDILOL [WHO-DD], SCHEMBL22293, GTPL551, KBioGR_001252, KBioSS_002145, MLS000758299, MLS000759508, MLS001424092, MLS006011886, orb422241, SPBio_001885, Carvedilol (JP17/USP/INN), Carvedilol - Bio-X trade mark, orb2893745, CARVEDILOL [ORANGE BOOK], SCHEMBL10082334, SCHEMBL29370188, SCHEMBL29687280, BDBM25759, HY-B0006R, KBio2_002145, KBio2_004713, KBio2_007281, KBio3_002323, CARVEDILOL [EP MONOGRAPH], MSK1388, CARVEDILOL [USP MONOGRAPH], GLXC-03245, HMS2051N03, HMS2089B09, HMS2093E12, HMS3261E15, HMS3269N11, HMS3393N03, HMS3413B14, HMS3655O14, HMS3677B14, HMS3715D15, HMS3750I15, HMS3884E12, HMS5080E13, Pharmakon1600-01504257, Carvedilol 1.0 mg/ml in Methanol, ALBB-038656, EX-A5746, HY-B0006, Tox21_500347, BBL029064, EBC-00687, MSK1388-100M, NSC758694, s1831, STK621453, Carvedilol for system suitability CRS, AKOS005554967, Carvedilol, >=98% (HPLC), solid, MSK1388-1000M, AC-1641, CCG-100917, CCG-207952, CS-1194, DB01136, FC11729, KS-1037, LP00347, NC00167, NSC 758694, SB17441, SDCCGSBI-0206771.P002, 1-(9H-carbazol-4-yloxy)-3-[(2-{[2-(methyloxy)phenyl]oxy}ethyl)amino]propan-2-ol, NCGC00167832-01, NCGC00167832-02, NCGC00167832-03, NCGC00167832-04, NCGC00167832-19, NCGC00261032-01, BC164291, SBI-0206771.P001, Carvedilol Solution in Methanol, 100ug/mL, DB-055704, DB-057556, DB-057557, C2260, Carvedilol Solution in Methanol, 1000ug/mL, NS00002339, SW197547-3, C06875, D00255, F19969, AB00639903-07, AB00639903-09, AB00639903_10, AB00639903_11, AB00639903_12, L001243, Q412534, SR-01000759289-5, SR-01000759289-6, SR-01000759289-9, BRD-A10977446-001-04-8, BRD-A10977446-001-05-5, BRD-A10977446-001-12-1, BRD-A10977446-001-13-9, BRD-A10977446-001-14-7, BRD-A10977446-011-01-3, BRD-A10977446-045-01-1, Z1515383337, Carvedilol, European Pharmacopoeia (EP) Reference Standard, Carvedilol, United States Pharmacopeia (USP) Reference Standard, 1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxy-phenoxy)-ethylamino]-propan-2-ol, 1-(9H-Carbozol-4-yloxy)-3-[[2-(2-methoxy phenoxy)ethyl]amino]-2-propanol, Carvedilol, Pharmaceutical Secondary Standard, Certified Reference Material, (+/-)-1-CARBAZOL-4-YLOXY)-3-((2-(O-METHOXYPHENOXY)ETHYL)AMINO)-2-PROPANOL, 1-(CARBAZOL-4-YLOXY)-3-((2-(O-METHOXY-PHENOXY)ETHYL)AMINO)-2-PROPANOL, Carvedilol for system suitability, European Pharmacopoeia (EP) Reference Standard, 107741-96-8, 2-PROPANOL, 1-(9H-CARBAZOL-4-YLOXY)-3-((2-(2-METHOXYPHENOXY)ETHYL)AMINO)-, (+/-)-

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
1-Butanol	288.15	-	3.027	[239]
1-Butanol	293.15	-	3.51	[239]
1-Butanol	298.15	-	4.087	[239]
1-Butanol	303.15	-	4.756	[239]
1-Butanol	308.15	-	5.479	[239]
1-Propanol	288.15	-	3.465	[239]
1-Propanol	293.15	-	4.303	[239]
1-Propanol	298.15	-	5.392	[239]
1-Propanol	303.15	-	6.574	[239]
1-Propanol	308.15	-	7.989	[239]
Acetone	278.15	-	3.62	[240]
Acetone	283.15	-	4.94	[240]
Acetone	288.15	-	70.55	[239]
Acetone	288.15	-	6.529	[240]
Acetone	293.15	-	82.5	[239]
Acetone	293.15	-	8.529	[240]
Acetone	298.15	-	96.7	[239]
Acetone	298.15	-	11.6	[240]
Acetone	303.15	-	111.8	[239]
Acetone	303.15	-	14.65	[240]
Acetone	308.15	-	127.0	[239]
Acetone	308.15	-	19.23	[240]
Acetone	313.15	-	24.8	[240]
Dichloromethane	288.15	-	16.27	[239]
Dichloromethane	293.15	-	21.27	[239]
Dichloromethane	298.15	-	27.15	[239]
Dichloromethane	303.15	-	34.97	[239]
Dichloromethane	308.15	-	45.15	[239]
Ethanol	278.15	-	4.39	[240]
Ethanol	283.15	-	5.99	[240]
Ethanol	288.15	-	4.742	[239]
Ethanol	288.15	-	7.849	[240]
Ethanol	293.15	-	5.899	[239]
Ethanol	293.15	-	9.977	[240]
Ethanol	298.15	-	7.354	[239]
Ethanol	298.15	-	12.85	[240]
Ethanol	303.15	-	8.831	[239]
Ethanol	303.15	-	16.99	[240]
Ethanol	308.15	-	10.84	[239]
Ethanol	308.15	-	21.03	[240]
Ethanol	313.15	-	26.61	[240]
Ethyl acetate	278.15	-	2.67	[240]
Ethyl acetate	283.15	-	3.63	[240]
Ethyl acetate	288.15	-	6.28	[239]
Ethyl acetate	288.15	-	6.115	[240]
Ethyl acetate	293.15	-	7.867	[239]
Ethyl acetate	293.15	-	7.784	[240]
Ethyl acetate	298.15	-	9.886	[239]
Ethyl acetate	298.15	-	9.93	[240]
Ethyl acetate	303.15	-	12.0	[239]
Ethyl acetate	303.15	-	12.09	[240]
Ethyl acetate	308.15	-	14.79	[239]
Ethyl acetate	308.15	-	15.16	[240]
Ethyl acetate	313.15	-	17.21	[240]
Isopropanol	288.15	-	2.25	[239]
Isopropanol	293.15	-	2.951	[239]
Isopropanol	298.15	-	3.838	[239]
Isopropanol	303.15	-	4.982	[239]
Isopropanol	308.15	-	6.49	[239]
Methanol	278.15	-	6.44	[240]
Methanol	283.15	-	8.84	[240]
Methanol	288.15	-	7.748	[239]
Methanol	288.15	-	11.52	[240]
Methanol	293.15	-	9.633	[239]
Methanol	293.15	-	15.1	[240]
Methanol	298.15	-	12.0	[239]
Methanol	298.15	-	20.09	[240]
Methanol	303.15	-	14.8	[239]
Methanol	303.15	-	25.45	[240]
Methanol	308.15	-	18.27	[239]
Methanol	308.15	-	32.53	[240]
Methanol	313.15	-	41.22	[240]
Propylene Glycol	288.15	-	7.679	[239]
Propylene Glycol	293.15	-	8.597	[239]
Propylene Glycol	298.15	-	9.617	[239]
Propylene Glycol	303.15	-	10.63	[239]
Propylene Glycol	308.15	-	11.69	[239]
Tetrahydrofuran	278.15	-	2.19	[240]
Tetrahydrofuran	283.15	-	3.09	[240]
Tetrahydrofuran	288.15	-	108.5	[239]
Tetrahydrofuran	288.15	-	4.28	[240]
Tetrahydrofuran	293.15	-	120.4	[239]
Tetrahydrofuran	293.15	-	5.911	[240]
Tetrahydrofuran	298.15	-	133.3	[239]
Tetrahydrofuran	298.15	-	8.318	[240]
Tetrahydrofuran	303.15	-	148.1	[239]
Tetrahydrofuran	303.15	-	11.24	[240]
Tetrahydrofuran	308.15	-	162.8	[239]
Tetrahydrofuran	308.15	-	14.87	[240]
Tetrahydrofuran	313.15	-	20.0	[240]
Water	278.15	-	452.0	[240]
Water	283.15	-	535.8	[240]
Water	288.15	-	645.8	[240]
Water	293.15	-	768.4	[240]
Water	298.15	-	933.3	[240]
Water	303.15	-	1104.0	[240]
Water	308.15	-	1311.5	[240]
Water	313.15	-	1534.4	[240]

Molecule 3D descriptors

Descriptor	Value
PMI1	2017.8719
PMI2	10634.5116
PMI3	11136.0743
NPR1	0.1812
NPR2	0.9550
RadiusOfGyration	5.4094
InertialShapeFactor	0.0005
Eccentricity	0.9834
Asphericity	0.5571
SpherocityIndex	0.2324
PBF	1.2357