Gliclazide

CAS Number: 21187-98-4

Molecular Mass: 323.4 g/mol

Formula: C₁₅H₂₁N₃O₃S

Smiles: Cc1ccc(S(=O)(=O)NC(=O)NN2CC3CCCC3C2)cc1

Synonymes:

Gliclazide, gliclazide, 21187-98-4, Glimicron, Diamicron, Gliclazida, S-852, DTXSID9023095, S-1702, 1-(3-Azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea, 1-(Hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea, CHEBI:31654, NSC-758673, J3.151H, SE-1702, Gliclazidum, SE 1702, DTXCID003095, Glyclazide, Gliklazid, S 1702, 1-(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-[(4-methylphenyl)sulfonyl]urea, S 852, Benzenesulfonamide, N-(((hexahydrocyclopenta(c)pyrrol-2(1H)-yl)amino)carbonyl)-4-methyl-, Benzenesulfonamide, N-[[(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)amino]carbonyl]-4-methyl-, Gen Gliclazide, Novo Gliclazide, Diamicron MR, 1-[(4-methylbenzene)sulfonyl]-3-{octahydrocyclopenta[c]pyrrol-2-yl}urea, Bilxona, Ziclaseg, Edicil, Glimil, Zicron, Vamju, Dacadis mr, Nazdol mr, Vitile xl, Zicron pr, 1-((4-methylbenzene)sulfonyl)-3-(octahydrocyclopenta(c)pyrrol-2-yl)urea, 1-(Hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-((4-methylphenyl)sulfonyl)urea, S852, RefChem:389010, A10BB09, 244-260-5, G4PX8C4HKV, S1702, MFCD00409893, Gliclazidum [INN-Latin], Gliclazida [INN-Spanish], 1-(3-Azabicyclo[3.3.0]oct-3-yl)-3-p-tolylsulphonylurea, 1-(3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-3-(4-methylphenyl)sulfonylurea, 1-[3-Azabicyclo[3.3.0]oct-3-yl]-3-p-toluenesulfonylurea, N-(hexahydrocyclopenta[c]pyrrol-2(1H)-ylcarbamoyl)-4-methylbenzenesulfonamide, Benzenesulfonamide,N-[[(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)amino]carbonyl]-4-methyl-, S1702, SE1702, N-((hexahydrocyclopenta[c]pyrrol-2(1H)-yl)carbamoyl)-4-methylbenzenesulfonamide, N-[[(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)amino]carbonyl]-4-methylbenzenesulfonamide, N-(4-Methylbenzenesulfonyl)-N'-(3-azabicyclo(3.3.0)oct-3-yl)urea, Gliclazide?, Glimicron (TN), SMR000542971, SR-01000816184, Unava, Diabrezide, , Glyclazide, , Diamicron, , Glimicron, , Nordialex, , Gliclazide CRS, NCGC00016751-01, Prestwick_869, CAS-21187-98-4, Gliclazide (Standard), Gliclazide (Diamicron), Spectrum_001478, SpecPlus_000870, Prestwick0_000558, Prestwick1_000558, Prestwick2_000558, Prestwick3_000558, Spectrum3_001862, Spectrum4_000598, Spectrum5_000753, Gliclazide (JP18/INN), SCHEMBL16387, BSPBio_000635, BSPBio_003304, KBioGR_001096, KBioSS_001958, MLS001215197, MLS001304077, MLS001304118, DivK1c_006966, Gliclazide, powder, >=98%, SPECTRUM1504145, SPECTRUM1505013, SPBio_002556, BPBio1_000699, CHEMBL427216, orb1308313, orb3139692, Urea, 1-(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)-, HY-B0753R, KBio1_001910, KBio2_001958, KBio2_004526, KBio2_007094, KBio3_002806, Gliclazide (S1702, Diamicron), HMS1569P17, HMS1922D15, HMS2090K16, HMS2096P17, HMS2855P09, HMS3656C22, HMS3713P17, HMS3744O13, HMS5081J09, Pharmakon1600-01504145, HY-B0753, MSK10066, Tox21_110590, 1-(4-methylbenzenesulfonyl)-3-{octahydrocyclopenta[c]pyrrol-2-yl}urea, BBL012275, BDBM50103512, EBC-80093, NSC758673, NSC813216, s2601, SBB066074, STK803142, AKOS003237903, AKOS016340698, Tox21_110590_1, AB05958, CCG-213918, DB01120, FG23666, KS-1067, NSC-813216, 1-(3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-3-(p-tolylsulfonyl)urea, N-[(hexahydrocyclopenta[c]pyrrol-2(1H)-ylamino)carbonyl]-4-methylbenzenesulfonamide, NCGC00095107-01, NCGC00095107-02, NCGC00095107-03, NCGC00095107-04, NCGC00095107-05, NCGC00095107-06, NCGC00095107-09, NCGC00095107-10, AC-12045, ST076805, SBI-0052662.P002, AB00053165, G0381, NS00002064, SW196994-3, D01599, D83168, AB00053165-09, AB00053165_10, AB00053165_11, EN300-7359575, F811940, Q290001, SR-01000816184-2, SR-01000816184-3, SR-01000816184-4, BRD-A61154809-001-04-3, BRD-A61154809-001-14-2, BRD-A61154809-001-15-9, BRD-A61154809-001-16-7, Gliclazide, British Pharmacopoeia (BP) Reference Standard, Gliclazide, European Pharmacopoeia (EP) Reference Standard, [(3-azabicyclo[3.3.0]oct-3-yl)amino]-N-[(4-methylphenyl)sulfonyl]carboxamide, N-(3-azabicyclo[3.3.0]oct-3-yl){[(4-methylphenyl)sulfonyl]amino}carboxamide, N-[(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)carbamoyl]-4-methylbenzene-1-sulfonamide, N-[[(H exahydrocylopenta[c]pyrrol-2(1H)-yl]amino]carbonyl ]-4-methylbenzenesulfonamide, BENZENESULFONAMIDE, N-[[(HEXAHYDROCYCLOPENTA[C]PYRROL-2(1H)-YL)AMINO]CARBONYL]-4-METHYL

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
1-Butanol	278.15	-	2.235	[267]
1-Butanol	283.15	-	2.81	[267]
1-Butanol	288.15	-	3.494	[267]
1-Butanol	293.15	-	4.354	[267]
1-Butanol	298.15	-	5.36	[267]
1-Butanol	303.15	-	6.715	[267]
1-Butanol	308.15	-	8.042	[267]
1-Butanol	313.15	-	9.932	[267]
1-Butanol	318.15	-	11.91	[267]
1-Propanol	278.15	-	2.877	[267]
1-Propanol	283.15	-	3.633	[267]
1-Propanol	288.15	-	4.5	[267]
1-Propanol	293.15	-	5.58	[267]
1-Propanol	298.15	-	6.97	[267]
1-Propanol	303.15	-	8.543	[267]
1-Propanol	308.15	-	10.16	[267]
1-Propanol	313.15	-	12.35	[267]
1-Propanol	318.15	-	14.82	[267]
2-Butanol	278.15	-	1.806	[267]
2-Butanol	283.15	-	2.29	[267]
2-Butanol	288.15	-	2.95	[267]
2-Butanol	293.15	-	3.75	[267]
2-Butanol	298.15	-	4.675	[267]
2-Butanol	303.15	-	5.801	[267]
2-Butanol	308.15	-	7.13	[267]
2-Butanol	313.15	-	8.911	[267]
2-Butanol	318.15	-	11.06	[267]
Acetone	278.15	-	40.07	[267]
Acetone	283.15	-	46.33	[267]
Acetone	288.15	-	54.17	[267]
Acetone	293.15	-	63.04	[267]
Acetone	298.15	-	73.62	[267]
Acetone	303.15	-	84.27	[267]
Acetone	308.15	-	96.64	[267]
Acetone	313.15	-	110.7	[267]
Acetone	318.15	-	127.1	[267]
Acetonitrile	278.15	-	10.81	[267]
Acetonitrile	283.15	-	13.21	[267]
Acetonitrile	288.15	-	16.28	[267]
Acetonitrile	293.15	-	19.69	[267]
Acetonitrile	298.15	-	23.99	[267]
Acetonitrile	303.15	-	28.86	[267]
Acetonitrile	308.15	-	33.78	[267]
Acetonitrile	313.15	-	39.69	[267]
Acetonitrile	318.15	-	47.73	[267]
Chloroform	278.15	-	253.3	[267]
Chloroform	283.15	-	279.5	[267]
Chloroform	288.15	-	305.6	[267]
Chloroform	293.15	-	337.7	[267]
Chloroform	298.15	-	368.3	[267]
Chloroform	303.15	-	402.6	[267]
Chloroform	308.15	-	440.1	[267]
Chloroform	313.15	-	481.5	[267]
Chloroform	318.15	-	527.3	[267]
Cyclohexanone	278.15	-	36.02	[267]
Cyclohexanone	283.15	-	42.61	[267]
Cyclohexanone	288.15	-	49.44	[267]
Cyclohexanone	293.15	-	57.51	[267]
Cyclohexanone	298.15	-	66.43	[267]
Cyclohexanone	303.15	-	76.9	[267]
Cyclohexanone	308.15	-	87.93	[267]
Cyclohexanone	313.15	-	101.7	[267]
Cyclohexanone	318.15	-	117.0	[267]
Dimethylformamide	278.15	-	258.0	[267]
Dimethylformamide	283.15	-	284.6	[267]
Dimethylformamide	288.15	-	309.9	[267]
Dimethylformamide	293.15	-	337.1	[267]
Dimethylformamide	298.15	-	363.8	[267]
Dimethylformamide	303.15	-	394.1	[267]
Dimethylformamide	308.15	-	426.4	[267]
Dimethylformamide	313.15	-	461.0	[267]
Dimethylformamide	318.15	-	500.2	[267]
Ethanol	278.15	-	4.168	[267]
Ethanol	283.15	-	5.108	[267]
Ethanol	288.15	-	6.277	[267]
Ethanol	293.15	-	7.607	[267]
Ethanol	298.15	-	9.342	[267]
Ethanol	303.15	-	11.15	[267]
Ethanol	308.15	-	13.6	[267]
Ethanol	313.15	-	16.07	[267]
Ethanol	318.15	-	19.35	[267]
Ethyl acetate	278.15	-	4.943	[267]
Ethyl acetate	283.15	-	5.84	[267]
Ethyl acetate	288.15	-	7.073	[267]
Ethyl acetate	293.15	-	8.219	[267]
Ethyl acetate	298.15	-	9.669	[267]
Ethyl acetate	303.15	-	11.47	[267]
Ethyl acetate	308.15	-	13.36	[267]
Ethyl acetate	313.15	-	15.41	[267]
Ethyl acetate	318.15	-	17.92	[267]
Ethyl formate	278.15	-	7.71	[267]
Ethyl formate	283.15	-	9.764	[267]
Ethyl formate	288.15	-	12.07	[267]
Ethyl formate	293.15	-	14.68	[267]
Ethyl formate	298.15	-	18.2	[267]
Ethyl formate	303.15	-	21.89	[267]
Ethyl formate	308.15	-	26.68	[267]
Ethyl formate	313.15	-	32.28	[267]
Ethyl formate	318.15	-	38.25	[267]
Isobutanol	278.15	-	1.491	[267]
Isobutanol	283.15	-	1.924	[267]
Isobutanol	288.15	-	2.495	[267]
Isobutanol	293.15	-	3.209	[267]
Isobutanol	298.15	-	3.981	[267]
Isobutanol	303.15	-	5.054	[267]
Isobutanol	308.15	-	6.235	[267]
Isobutanol	313.15	-	7.774	[267]
Isobutanol	318.15	-	9.801	[267]
Isopropanol	278.15	-	1.429	[267]
Isopropanol	283.15	-	1.879	[267]
Isopropanol	288.15	-	2.461	[267]
Isopropanol	293.15	-	3.122	[267]
Isopropanol	298.15	-	3.975	[267]
Isopropanol	303.15	-	5.039	[267]
Isopropanol	308.15	-	6.273	[267]
Isopropanol	313.15	-	7.951	[267]
Isopropanol	318.15	-	9.943	[267]
Methanol	278.15	-	9.921	[267]
Methanol	283.15	-	12.04	[267]
Methanol	288.15	-	14.32	[267]
Methanol	293.15	-	17.28	[267]
Methanol	298.15	-	20.42	[267]
Methanol	303.15	-	24.08	[267]
Methanol	308.15	-	28.16	[267]
Methanol	313.15	-	33.5	[267]
Methanol	318.15	-	38.69	[267]
Methyl acetate	278.15	-	9.555	[267]
Methyl acetate	283.15	-	11.73	[267]
Methyl acetate	288.15	-	13.96	[267]
Methyl acetate	293.15	-	17.12	[267]
Methyl acetate	298.15	-	20.29	[267]
Methyl acetate	303.15	-	23.77	[267]
Methyl acetate	308.15	-	28.12	[267]
Methyl acetate	313.15	-	33.48	[267]
Methyl acetate	318.15	-	38.97	[267]
Tetrahydrofuran	278.15	-	74.4	[267]
Tetrahydrofuran	283.15	-	89.29	[267]
Tetrahydrofuran	288.15	-	109.3	[267]
Tetrahydrofuran	293.15	-	130.8	[267]
Tetrahydrofuran	298.15	-	158.0	[267]
Tetrahydrofuran	303.15	-	190.5	[267]
Tetrahydrofuran	308.15	-	222.5	[267]
Tetrahydrofuran	313.15	-	263.0	[267]
Tetrahydrofuran	318.15	-	317.2	[267]
Toluene	278.15	-	0.9496	[267]
Toluene	283.15	-	1.214	[267]
Toluene	288.15	-	1.527	[267]
Toluene	293.15	-	1.932	[267]
Toluene	298.15	-	2.39	[267]
Toluene	303.15	-	2.949	[267]
Toluene	308.15	-	3.563	[267]
Toluene	313.15	-	4.47	[267]
Toluene	318.15	-	5.375	[267]

Molecule 3D descriptors

Descriptor	Value
PMI1	1163.7345
PMI2	4000.5718
PMI3	4685.2774
NPR1	0.2484
NPR2	0.8539
RadiusOfGyration	3.9022
InertialShapeFactor	0.0007
Eccentricity	0.9687
Asphericity	0.4312
SpherocityIndex	0.1890
PBF	0.8995