Progesterone

CAS Number: 57-83-0

Molecular Mass: 314.5 g/mol

Formula: C₂₁H₃₀O₂

Smiles: CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C

Synonymes:

Progesterone, progesterone, 57-83-0, Pregn-4-ene-3,20-dione, Agolutin, Crinone, Progestin, Utrogestan, Luteol, 4-Pregnene-3,20-dione, Gestormone, Glanducorpin, Prometrium, Syngesterone, Corlutin, Cyclogest, Gestone, Corlutina, Corluvite, Flavolutan, Fologenon, Gynolutone, Hormoflaveine, Hormoluton, Lucorteum, Luteostab, Lutociclina, Lutocyclin, Pregnenedione, Progestasert, Progesterol, Progesteronum, Progestone, Progestron, Corporin, Gesterol, Gestron, Gynlutin, Luteodyn, Luteogan, Luteopur, Luteosan, Luteovis, Lutidon, Nalutron, Lutin, Lutocyclin M, Bio-luton, Lipo-Lutin, Luteocrin normale, Methylpregnone, Progestosol, Progestronol, Syngestrets, Lingusorbs, Luteinique, Lutocylin, Lutoform, Lutogyl, Lutromone, Membrettes, Piaponon, Primolut, Progekan, Prolets, Prolidon, Proluton, Protormone, Syntolutan, Lutren, Lucorteum Sol, Prochieve, Prolutone, Synovex S, Endometrin, Gesterol 100, Gynoluton, Projestaject, 17alpha-Progesterone, Percutacrine Luteinique, Progeston, Pregnene-3,20-dione, Akrolutin, Gestiron, Progestogel, 3,20-Pregnene-4, (S)-Progesterone, Progesteron, Lutocylol, Progestol, Luteum, Crinone progesterone gel, Gelbkoerperhormon, NSC-9704, Progesterona, Vitarrine, (S)-4-Pregnene-3,20-dione, Delta(4)-pregnene-3,20-dione, (S)-Pregn-4-en-3,20-dione, beta-Progesterone, Lutogynon, Progesterone, micronized, DTXSID3022370, 17alpha-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione, NSC-64377, MILPROSA, 4G7DS2Q64Y, CHEBI:17026, NSC9704, delta(Sup4)-pregnene-3,20-dione, (8S,9S,10R,13S,14S,17S)-17-Acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one, NSC64377, U 3672, DTXCID902370, Natural Progesterone, delta4-Pregnene-3,20-dione, Syngestrone, Lutigest, Progesta-care, Progesto-Life, Lutocylin M, Progesterone Combo, Serenity for women, Progesterone Phenolic, Synthetic Progestagen, Progesterone 1538, (8S,9S,10R,13S,14S,17S)-17-Acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta(a)phenanthren-3-one, RefChem:6165, Therapeutic Progesterone, P25 Progesterone Cream, P50 Progesterone Cream, P75 Progesterone Cream, EAZI-BREED CIDR Sheep, EAZI-BREED CIDR Cattle, P75 Lav Progesterone Cream, Advanced Formula Progesto-Life, CHEBI:59826, EAZI-BREED CIDR Sheep Insert, EAZI-BREED CIDR Cattle Insert, G03DA04, DTXCID801775313, P75 Maxx with Retinol All Natural Progesterone 75 Cream, (1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltetracyclo(8.7.0.02,7.011,15)heptadec-6-en-5-one, 200-350-6, DTXSID001346637, Lutex, Gesterol 50, Colprosterone, Cyclogesterin, Prolutin, Lugesteron, Lutocuclin M, Luteol (VAN), .beta.-Progesterone, Percutacrine, Progeffik, Utrogest, Estima, Progesteronum [INN-Latin], Progesterona [INN-Spanish], delta(sup 4)-Pregnene-3,20-dione, C21H30O2, CCRIS 533, Prontogest, 17.alpha.-Progesterone, HSDB 3389, Progesterone [Progestins], 4-Pregnen-3,20-dione, AI3-51682, Prometrium (TN), Pregn-4-en-3,20-dione, MFCD00003658, Crinone (TN), 6alpha-Methylpregn-4-en-17alpha-ol-3,20-dione, .delta.4-Pregnene-3,20-dione, Progesterone (Standard), Pregn-4-ene-3,20-dione, 17alpha-hydroxy-6alpha-methyl-, component of Cyclogesterin, .delta.(sup4)-Pregnene-3,20-dione, CHEMBL103, D4-Pregnene-3,20-dione, MLS000028517, (8S,9S,10R,13S,14S,17S)-17-Acetyl-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one, NCGC00015785-04, SMR000058345, 6.alpha.-Methylpregn-4-en-17.alpha.-ol-3,20-dione, 17.alpha.-Hydroxy-6.alpha.-methylpregn-4-ene-3,20-dione, 17a-Progesterone, Duraprogen, Pregesterone, Progestan, Pregn-4-ene-3,20-dione, 17.alpha.-hydroxy-6.alpha.-methyl-, (1S,10S,11S,14S,15S,2R)-14-acetyl-2,15-dimethyl-5-oxotetracyclo[8.7.0.0<2,7>.0 <11,15>]heptadec-6-ene, SMR000653542, CIDR, Progesterone (Prometrium), WLN: L E5 B666 OV MUTJ A1 E1 FV1, SR-01000000088, SR-01000076054, NSC 9704, EINECS 200-350-6, NSC 64377, Pregn-4-ene-3, 17.alpha.-hydroxy-6.alpha.-methyl-, BHR-100, UNII-4G7DS2Q64Y, Progestrel, Lipolutin, Lutinus, Progesterone RS, Progesterone CRS, 1dbb, CAS-57-83-0, Progesterone [USP:INN:BAN:JAN], racemic progesterone, Prestwick_411, Progesterone solution, mpp22, 2aa6, 4bb2, Opera_ID_292, Progesterone, >=99%, Prestwick0_000477, Prestwick1_000477, Prestwick2_000477, Prestwick3_000477, Spectrum5_002053, PROGESTERONE [MI], Cyclogesterin (Salt/Mix), PROGESTERONE [INN], PROGESTERONE [JAN], bmse000482, Epitope ID:116051, EC 200-350-6, PROGESTERONE [HSDB], SCHEMBL7671, ?4-Pregnene-3,20-dione, PROGESTERONE [VANDF], BIDD:PXR0094, Lopac0_000895, BSPBio_000614, PROGESTERONE [MART.], HUMAN SERUM (progesterone), MLS000758277, MLS001074187, MLS001423982, MLS002222367, BIDD:ER0547, P0130_SIGMA, PROGESTERONE [USP-RS], PROGESTERONE [WHO-DD], PROGESTERONE [WHO-IP], SPBio_002553, .delta.-Pregnene-3,20-dione, BDBM8903, BPBio1_000676, GTPL2377, Hydroxyprogesterone Caproic acid, orb1310573, orb3025169, SCHEMBL7610853, SCHEMBL8711607, HY-N0437R, Progesterone (JP18/USP/INN), BHR-310, ETI-411, MSK2223, PROGESTERONE [GREEN BOOK], 1a28, 1h60, HMS1569O16, HMS2051O05, HMS2090J07, HMS2096O16, HMS2230F23, HMS2233P11, HMS3262D12, HMS3713O16, Pregnene, 3,20-dione-delta^4-, PROGESTERONE [ORANGE BOOK], PROGESTERONE [EP MONOGRAPH], Progesterone in human serum (high), BIJUVA COMPONENT PROGESTERONE, HY-N0437, PROGESTERONE [USP MONOGRAPH], Tox21_113157, Tox21_201792, Tox21_300307, Tox21_500895, AC-700, CMC_13406, EBC-06111, LMST02030159, MSK2223-100A, Progesterone, 1mg/ml in Acetonitrile, PROGESTERONUM [WHO-IP LATIN], s1705, SBB012538, AKOS015894908, MSK2223-1000A, Progesterone, 4-Pregnene-3,20-dione, CCG-100766, CS-1937, DB00396, DR-2011, FD12045, FP27173, LP00895, NC00016, SDCCGSBI-0050870.P002, Progesterone 1.0 mg/ml in Acetonitrile, NCGC00022185-03, NCGC00022185-04, NCGC00022185-05, NCGC00022185-06, NCGC00022185-07, NCGC00022185-08, NCGC00022185-09, NCGC00022185-10, NCGC00022185-11, NCGC00022185-12, NCGC00022185-14, NCGC00022185-21, NCGC00090798-01, NCGC00090798-02, NCGC00254120-01, NCGC00259341-01, NCGC00261580-01, (8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one, AS-12660, CPD000058345, NCI60_042166, ST069329, FE-999913, CS-0694805, EU-0100895, NS00010899, P0478, T0478, (14beta,17alpha)-pregn-4-ene-3,20-dione, Progesterone, meets USP testing specifications, Progesterone, Vetec(TM) reagent grade, 98%, C00410, D00066, P 0130, Q26963, S00293, Progesterone Solution in Acetonitrile, 100ug/mL, Progesterone, VETRANAL(TM), analytical standard, F374675, Progesterone Solution in Acetonitrile, 1000ug/mL, SR-01000000088-5, SR-01000000088-6, SR-01000076054-1, SR-01000076054-4, BRD-K64994968-001-03-6, 32104FB6-BF81-4F6E-83C2-024DEEAEB272, Z1501485353, Progesterone, British Pharmacopoeia (BP) Reference Standard, Progesterone, powder, BioReagent, suitable for cell culture, Progesterone, European Pharmacopoeia (EP) Reference Standard, Progesterone, gamma-irradiated, BioXtra, suitable for cell culture, Progesterone, United States Pharmacopeia (USP) Reference Standard, Progesterone-Water Soluble, powder, BioReagent, suitable for cell culture, Progesterone for peak identification, European Pharmacopoeia (EP) Reference Standard, Progesterone for system suitability, European Pharmacopoeia (EP) Reference Standard, Progesterone, Pharmaceutical Secondary Standard, Certified Reference Material, (1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one, 137940-28-4

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
1,4-Dioxane	288.15	-	242.9	[270]
1,4-Dioxane	293.15	-	290.9	[270]
1,4-Dioxane	298.15	-	343.1	[270]
1,4-Dioxane	303.15	-	406.3	[270]
1,4-Dioxane	308.15	-	481.1	[270]
1,4-Dioxane	313.15	-	566.5	[270]
1,4-Dioxane	318.15	-	663.1	[270]
1,4-Dioxane	323.15	-	777.5	[270]
1-Butanol	278.15	-	24.78	[270]
1-Butanol	283.15	-	33.17	[270]
1-Butanol	288.15	-	44.52	[270]
1-Butanol	293.15	-	57.11	[270]
1-Butanol	298.15	-	73.83	[270]
1-Butanol	303.15	-	93.85	[270]
1-Butanol	308.15	-	121.3	[270]
1-Butanol	313.15	-	154.9	[270]
1-Butanol	318.15	-	195.5	[270]
1-Butanol	323.15	-	244.5	[270]
1-Propanol	278.15	-	22.62	[270]
1-Propanol	283.15	-	30.39	[270]
1-Propanol	288.15	-	41.36	[270]
1-Propanol	293.15	-	55.89	[270]
1-Propanol	298.15	-	72.89	[270]
1-Propanol	303.15	-	96.59	[270]
1-Propanol	308.15	-	125.5	[270]
1-Propanol	313.15	-	161.8	[270]
1-Propanol	318.15	-	209.0	[270]
1-Propanol	323.15	-	266.8	[270]
Acetone	278.15	-	63.34	[270]
Acetone	283.15	-	82.7	[270]
Acetone	288.15	-	107.8	[270]
Acetone	293.15	-	137.4	[270]
Acetone	298.15	-	175.5	[270]
Acetone	303.15	-	219.0	[270]
Acetone	308.15	-	275.4	[270]
Acetone	313.15	-	341.6	[270]
Acetone	318.15	-	427.7	[270]
Acetone	323.15	-	535.4	[270]
Acetonitrile	278.15	-	44.11	[270]
Acetonitrile	283.15	-	61.79	[270]
Acetonitrile	288.15	-	80.25	[270]
Acetonitrile	293.15	-	108.4	[270]
Acetonitrile	298.15	-	143.0	[270]
Acetonitrile	303.15	-	185.8	[270]
Acetonitrile	308.15	-	241.7	[270]
Acetonitrile	313.15	-	311.6	[270]
Acetonitrile	318.15	-	399.6	[270]
Acetonitrile	323.15	-	510.2	[270]
Ethanol	278.15	-	18.51	[270]
Ethanol	283.15	-	24.91	[270]
Ethanol	288.15	-	33.96	[270]
Ethanol	293.15	-	46.7	[270]
Ethanol	298.15	-	60.7	[270]
Ethanol	303.15	-	79.18	[270]
Ethanol	308.15	-	104.0	[270]
Ethanol	313.15	-	135.7	[270]
Ethanol	318.15	-	172.5	[270]
Ethanol	323.15	-	223.6	[270]
Ethyl acetate	278.15	-	47.11	[270]
Ethyl acetate	283.15	-	57.94	[270]
Ethyl acetate	288.15	-	70.98	[270]
Ethyl acetate	293.15	-	87.71	[270]
Ethyl acetate	298.15	-	105.7	[270]
Ethyl acetate	303.15	-	128.6	[270]
Ethyl acetate	308.15	-	155.5	[270]
Ethyl acetate	313.15	-	187.5	[270]
Ethyl acetate	318.15	-	223.4	[270]
Ethyl acetate	323.15	-	268.6	[270]
Heptane	278.15	-	0.2449	[270]
Heptane	283.15	-	0.3912	[270]
Heptane	288.15	-	0.607	[270]
Heptane	293.15	-	0.9126	[270]
Heptane	298.15	-	1.317	[270]
Heptane	303.15	-	1.939	[270]
Heptane	308.15	-	2.843	[270]
Heptane	313.15	-	4.149	[270]
Heptane	318.15	-	5.932	[270]
Heptane	323.15	-	8.336	[270]
Isopropanol	278.15	-	13.15	[270]
Isopropanol	283.15	-	18.61	[270]
Isopropanol	288.15	-	25.56	[270]
Isopropanol	293.15	-	34.86	[270]
Isopropanol	298.15	-	47.45	[270]
Isopropanol	303.15	-	63.05	[270]
Isopropanol	308.15	-	83.81	[270]
Isopropanol	313.15	-	111.3	[270]
Isopropanol	318.15	-	144.5	[270]
Isopropanol	323.15	-	189.3	[270]
Methanol	278.15	-	18.35	[270]
Methanol	283.15	-	26.41	[270]
Methanol	288.15	-	37.07	[270]
Methanol	293.15	-	52.84	[270]
Methanol	298.15	-	71.66	[270]
Methanol	303.15	-	98.96	[270]
Methanol	308.15	-	134.0	[270]
Methanol	313.15	-	181.3	[270]
Methanol	318.15	-	239.5	[270]
Methanol	323.15	-	321.6	[270]
Tetrahydrofuran	278.15	-	250.6	[270]
Tetrahydrofuran	283.15	-	295.5	[270]
Tetrahydrofuran	288.15	-	346.0	[270]
Tetrahydrofuran	293.15	-	403.0	[270]
Tetrahydrofuran	298.15	-	469.8	[270]
Tetrahydrofuran	303.15	-	546.2	[270]
Tetrahydrofuran	308.15	-	634.0	[270]
Tetrahydrofuran	313.15	-	735.1	[270]
Tetrahydrofuran	318.15	-	848.5	[270]
Tetrahydrofuran	323.15	-	984.9	[270]
Toluene	278.15	-	260.4	[270]
Toluene	283.15	-	298.2	[270]
Toluene	288.15	-	339.4	[270]
Toluene	293.15	-	385.4	[270]
Toluene	298.15	-	438.6	[270]
Toluene	303.15	-	500.3	[270]
Toluene	308.15	-	561.4	[270]
Toluene	313.15	-	646.2	[270]
Toluene	318.15	-	733.5	[270]
Toluene	323.15	-	830.8	[270]

Molecule 3D descriptors

Descriptor	Value
PMI1	734.5976
PMI2	3883.7007
PMI3	4247.7719
NPR1	0.1729
NPR2	0.9143
RadiusOfGyration	3.7546
InertialShapeFactor	0.0012
Eccentricity	0.9849
Asphericity	0.5697
SpherocityIndex	0.2563
PBF	0.8686