Malic acid

CAS Number: 6915-15-7

Molecular Mass: 134.09 g/mol

Formula: C₄H₆O₅

Smiles: O=C(O)CC(O)C(=O)O

Synonymes:

Malic acid, malic acid, 6915-15-7, 2-Hydroxybutanedioic acid, hydroxysuccinic acid, Butanedioic acid, hydroxy-, Malic acid, DL-, Kyselina jablecna, hydroxybutanedioic acid, Pomalus acid, alpha-Hydroxysuccinic acid, Deoxytetraric acid, Hydroxybutandisaeure, Monohydroxybernsteinsaeure, Succinic acid, hydroxy-, (+-)-Malic acid, Malicum acidum, Pomalous acid, d,l-malic acid, FEMA No. 2655, 2-Hydroxyethane-1,2-dicarboxylic acid, Kyselina hydroxybutandiova, (+-)-Hydroxysuccinic acid, NSC-25941, 817L1N4CKP, INS NO.296, DTXSID0027640, E296, INS NO. 296, INS-296, butanedioic acid, 2-hydroxy-, CHEBI:6650, DTXCID107640, E-296, hydron, 2-hydroxybutanedioate, Malic Acid 1524, RefChem:5979, MOOYAM AHA BHA FACE SERUM, 210-514-9, 230-022-8, DL-malic acid, 617-48-1, malate, 2-Hydroxysuccinic acid, DL-2-hydroxybutanedioic acid, dl-Hydroxybutanedioic acid, Musashi-no-Ringosan, Caswell No. 537, R,S(+-)-Malic acid, Kyselina jablecna [Czech], Malic acid [NF], FDA 2018, Apple acid, (+/-)-Malic acid, Kyselina hydroxybutandiova [Czech], L-Malic acid-1-13C, EPA Pesticide Chemical Code 051101, AI3-06292, MFCD00064212, BUTANEDIOIC ACID, HYDROXY-, (S)-, MLS000084707, (+-)-1-Hydroxy-1,2-ethanedicarboxylic acid, NSC25941, Malic acid (NF), SMR000019054, DL-Apple Acid, (R)-Hydroxybutanedioic acid, (S)-Hydroxybutanedioic acid, C4H6O5, R-Malic acid, FEMA Number 2655, CAS-6915-15-7, CCRIS 2950, CCRIS 6567, (+/-)-2-Hydroxysuccinic acid, HSDB 1202, EINECS 210-514-9, EINECS 230-022-8, NSC 25941, Hydroxybutanedioic acid, (-)-, UNII-817L1N4CKP, Aepfelsaeure, malate acid, Hydroxybutanedioic acid, (+-)-, H2mal, Racemic malic acid, .+-.-Malic acid, Malic acid (Standard), Opera_ID_805, 2-hydroxyl-succinic acid, DL-Malic acid, 99%, MALIC ACID [II], MALIC ACID [MI], MALIC ACID,(DL), 2-Hydroxydicarboxylic acid, MALIC ACID [FCC], SCHEMBL856, 2-hydroxy-butanedioic acid, bmse000046, bmse000904, EC 210-514-9, EC 230-022-8, MALIC ACID [VANDF], Malic acid-, (L-form)-, DL-Malic acid, >=99%, Oprea1_130558, Oprea1_624131, MALIC ACID [USP-RS], MALIC ACID [WHO-DD], Butanedioic acid, (.+-.)-, GTPL2480, orb1304684, orb3139813, SCHEMBL6575196, SCHEMBL7523596, CHEMBL1455497, SCHEMBL10591713, SCHEMBL11285307, SCHEMBL27819134, BDBM92495, HY-Y1311R, MSK4414, MALIC ACID [EP MONOGRAPH], MALIC ACID [USP IMPURITY], DL-Malic acid, FCC, >=99%, HMS2358H06, HMS3371C13, HMS5086O13, DL-Malic acid, analytical standard, HY-Y1311, STR03457, Tox21_201536, Tox21_300372, Butenedioic acid, hydroxy-, (2S)-, EBC-44214, s9001, STL283959, HYDROXYBUTANEDIOIC ACID [HSDB], AKOS000120085, AKOS017278471, CCG-266122, DB12751, FM25003, T2S0850, DL-Malic acid, ReagentPlus(R), 99%, NCGC00043225-02, NCGC00043225-03, NCGC00254259-01, NCGC00259086-01, DL-Malic acid, >=98% (capillary GC), HYDROXYBUTANEDIOIC ACID, (+/-)-, DL-Malic acid, ReagentPlus(R), >=99%, DB-016133, DL-Malic acid 1000 microg/mL in Methanol, DL-Malic acid, USP, 99.0-100.5%, CS-0017784, EU-0067046, M0020, NS00008011, DL-Malic acid, SAJ first grade, >=99.0%, EN300-19229, C00711, C03668, D04843, DL-Malic acid, Vetec(TM) reagent grade, 98%, AB00443952-12, Malic acid, meets USP/NF testing specifications, F364219, L023999, Q190143, D-Hydroxysuccinic acid, (R)-Hydroxybutanedioic acid, BRD-A18396475-001-15-3, 0C9A2DC0-FEA2-4864-B98B-0597CDD0AD06, F0918-0088, Z104473230, Malic acid, United States Pharmacopeia (USP) Reference Standard, MALIC ACID (CONSTITUENT OF CRANBERRY LIQUID PREPARATION) [DSC], Malic acid, Pharmaceutical Secondary Standard, Certified Reference Material, DL-Malic acid, meets analytical specification of FCC, E296, 99-100.5% (alkalimetric)

Bioactivity: -

Solubility in Different Solvents

Solvent	Temperature [K]	Crystal form	Solubility [mg/mL]	Reference
1,4-Dioxane	303.2	-	253.0	[37]
1,4-Dioxane	308.2	-	279.6	[37]
1,4-Dioxane	313.2	-	293.0	[37]
1,4-Dioxane	318.2	-	308.9	[37]
1,4-Dioxane	323.2	-	327.2	[37]
1,4-Dioxane	328.2	-	359.4	[37]
1,4-Dioxane	333.2	-	400.0	[37]
Acetonitrile	303.2	-	18.0	[37]
Acetonitrile	308.2	-	23.0	[37]
Acetonitrile	313.2	-	27.6	[37]
Acetonitrile	318.2	-	29.9	[37]
Acetonitrile	323.2	-	37.3	[37]
Acetonitrile	328.2	-	42.0	[37]
Acetonitrile	333.2	-	51.7	[37]
Ethanol	298.15	-	279.7	[41]
Ethanol	303.15	-	310.0	[41]
Ethanol	303.2	-	203.0	[37]
Ethanol	308.15	-	355.7	[41]
Ethanol	308.2	-	226.0	[37]
Ethanol	313.15	-	390.4	[41]
Ethanol	313.2	-	252.4	[37]
Ethanol	318.15	-	441.5	[41]
Ethanol	318.2	-	290.3	[37]
Ethanol	323.15	-	500.9	[41]
Ethanol	323.2	-	305.8	[37]
Ethanol	328.15	-	576.4	[41]
Ethanol	328.2	-	327.1	[37]
Ethanol	333.15	-	644.8	[41]
Ethanol	333.2	-	339.8	[37]
Isopropanol	303.2	-	64.7	[37]
Isopropanol	308.2	-	81.2	[37]
Isopropanol	313.2	-	99.7	[37]
Isopropanol	318.2	-	130.0	[37]
Isopropanol	323.2	-	176.0	[37]
Isopropanol	328.2	-	225.4	[37]
Isopropanol	333.2	-	259.2	[37]
Tetrahydrofuran	303.2	-	276.4	[37]
Tetrahydrofuran	308.2	-	299.3	[37]
Tetrahydrofuran	313.2	-	379.9	[37]
Tetrahydrofuran	318.2	-	397.2	[37]
Tetrahydrofuran	323.2	-	445.4	[37]
Tetrahydrofuran	328.2	-	484.8	[37]
Tetrahydrofuran	333.2	-	531.0	[37]
Water	278.15	-	941.6	[40]
Water	283.15	-	1028.2	[40]
Water	288.15	-	1128.9	[40]
Water	293.15	-	1264.1	[40]
Water	298.15	-	1390.5	[40]
Water	298.15	-	1310.0	[41]
Water	303.15	-	1497.5	[40]
Water	303.15	-	1422.0	[41]
Water	303.2	-	523.0	[37]
Water	308.15	-	1635.0	[40]
Water	308.15	-	1602.0	[41]
Water	308.2	-	677.0	[37]
Water	313.15	-	1818.7	[40]
Water	313.15	-	1800.0	[41]
Water	313.2	-	873.3	[37]
Water	318.15	-	1995.0	[41]
Water	318.2	-	1118.0	[37]
Water	318.65	-	1951.7	[40]
Water	323.15	-	2212.9	[40]
Water	323.15	-	2184.0	[41]
Water	323.2	-	1335.0	[37]
Water	328.15	-	2422.2	[40]
Water	328.15	-	2433.0	[41]
Water	328.2	-	1500.0	[37]
Water	333.15	-	2694.4	[40]
Water	333.15	-	2720.0	[41]
Water	333.2	-	1646.0	[37]
Water	338.15	-	3037.8	[40]

Molecule 3D descriptors

Descriptor	Value
PMI1	183.2294
PMI2	470.9523
PMI3	563.2885
NPR1	0.3253
NPR2	0.8361
RadiusOfGyration	2.1307
InertialShapeFactor	0.0046
Eccentricity	0.9456
Asphericity	0.3181
SpherocityIndex	0.2920
PBF	0.4897