Estriol
CAS Number: 50-27-1
Molecular Mass: 288.4 g/mol
Formula: C18H24O3
Smiles: C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1C[C@@H](O)[C@@H]2O
Synonymes:
Estriol, estriol, 50-27-1, Oestriol, Trihydroxyestrin, Aacifemine, Estratriol, Ovestrion, Tridestrin, Destriol, Ovestin, Theelol, Hormomed, Klimoral, Oestratriol, Orestin, Triovex, Ortho-Gynest, Hemostyptanon, Oestriolum, Overstin, 16alpha-Hydroxyestradiol, Deuslon-A, Estriel, 16alpha,17beta-Estriol, Colpogyn, 16-alpha-Hydroxyestradiol, 16alpha-Hydroxy-17beta-estradiol, 16alpha-Hydroxyoestradiol, 16alpha,17beta-Oestriol, Incurin, (16alpha,17beta)-Estra-1,3,5(10)-triene-3,16,17-triol, 16-alpha,17-beta-Estriol, 16-alpha,17-beta-Oestriol, 3,16alpha,17beta-Estriol, NSC-12169, Ovesterin, Ovo-vinces, Klimax E, 3,16alpha,17beta-Trihydroxy-1,3,5(10)-estratriene, Estra-1,3,5(10)-triene-3,16alpha,17beta-triol, Colpovister, OeKolp, Estra-1,3,5(10)-triene-3,16,17-triol, DTXSID9022366, 1,3,5(10)-Estratriene-3,16-alpha,17beta-triol, CHEBI:27974, FB33469R8E, 3,16alpha,17beta-trihydroxy-Delta(1,3,5)-estratriene, (8R,9S,13S,14S,16R,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol, DTXCID002366, Estra-1,3,5(10)-triene-3,16,17-triol, (16alpha,17beta)-, Gynest, Estro-Life, (8R,9S,13S,14S,16R,17R)-13-methyl-6,7,8,9,11,12,14,15,16, 17-decahydrocyclopenta(a)phenanthrene-3,16,17-triol, (8R,9S,13S,14S,16R,17R)-13-methyl-6,7,8,9,11,12,14,15,16, 17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol, (8R,9S,13S,14S,16R,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta(a)phenanthrene-3,16,17-triol, Estriol 5.0 Cream, LMNOOP Feminine Cream, RefChem:55145, 16alpha,17beta Estriol, 16beta Hydroxy Estradiol, 16beta-Hydroxy-Estradiol, 16 alpha Hydroxy Estradiol, 16-alpha-Hydroxy-Estradiol, Advanced Formula Estro-Life, (16beta,17beta)-Estra-1,3,5(10)-Triene-3,16,17-Triol, (1S,10R,11S,13R,14R,15S)-15-methyltetracyclo(8.7.0.02,7.011,15)heptadeca-2(7),3,5-triene-5,13,14-triol, 200-022-2, Orgastyptin, Thulol, Gynaesan, Hormonin, Trihydroxyoestrin, Estriolo [Italian], Estriolo, Estriol, unconjugated, 16-alpha-Hydroxyoestradiol, Deuslon A, 3,16-alpha,17-beta-Estriol, 3,16-alpha,17-beta-Oestriol, 16.alpha.-Hydroxyestradiol, 16.alpha.,17.beta.-Estriol, 16.alpha.-Estriol, MFCD00003691, Gynasan, oestriol., 1,3,5-Estratriene-3beta,16alpha,17beta-triol, 1,3,5-Oestratriene-3beta,16alpha,17beta-triol, A 13610, Estra-1,3,5(10)-trien-3,16alpha,17beta-triol, Oestra-1,3,5(10)-triene-3,16alpha,17beta-triol, 16.alpha.-Hydroxyoestradiol, 3,16alpha,17beta-Trihydroxy-delta-1,3,5-oestratriene, 3,16-alpha,17-beta-Trihydroxy-delta-1,3,5-estratriene, 3,16-alpha,17-beta-Trihydroxy-delta-1,3,5-oestratriene, 3,16-alpha,17-beta-Trihydroxyestra-1,3,5(10)-triene, 3,16-alpha,17-beta-Trihydroxyoestra-1,3,5(10)-triene, Estriol (Standard), (16alpha,17beta)-Oestra-1,3,5(10)-triene-3,16,17-triol, 1,3,5(10)-Estratriene-3,16alpha,17beta-Triol, 16.alpha.,17.beta.-Oestriol, OE3, Oestra-1,3,5(10)-triene-3,16-alpha,17-beta-triol, 16.alpha.-Hydroxy-17.beta.-estradiol, NSC12169, (8R,9S,13S,14S,16R,17R)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,16,17-triol, 3,16.alpha.,17.beta.-Estriol, 16a-Hydroxyestradiol, Holin V, 3,17.beta.-Estriol, CCRIS 284, Estriel (TN), 16-Hydroxyestradiol, Oestriol [Steroidal oestrogens], Estra-1,3,5(10)-triene-3,16,17-triol, (16.alpha.,17.beta.)-, HSDB 3590, SR-01000721851, EINECS 200-022-2, NSC 12169, 1,3,5(10)-Estratriene-3,16.alpha.,17.beta.-triol, Estra-1,3,5(10)-trien-3,16.alpha.,17.beta.-triol, Estra-1,3,5(10)-triene-3,16.alpha.,17.beta.-triol, 1,3,5(10)-ESTRATRIENE-3,16,17-TRIOL, 1,3,5-Estratriene-3.beta.,16-.alpha.,17-.beta.-triol, 1,3,5-Oestratriene-3-.beta.,16.alpha.,17.beta.-triol, 3,16.alpha.,17.beta.-Trihydroxy-1,3,5(10)-estratriene, 3,16.alpha.,17.beta.-Trihydroxyestra-1,3,5(10)-triene, BRN 2508172, Oestra-1,3,5(10)-triene-3,16.alpha., 17.beta.-triol, (16a,17b)-Estra-1,3,5[10]-triene-3,16,17-triol, 3,16.alpha.,17.beta.-Trihydroxy-.delta.-1,3,5-estratriene, Acifemine, Ovestinon, Trimesta, 3,16.alpha.,17.beta.-Trihydroxy-.delta.-1,3,5-oestratriene, UNII-FB33469R8E, (16A,17B)-ESTRA-1,3,5(10)-TRIENE-3,16,17-TRIOL, (16.alpha.,17.beta.)-Estra-1,3,5(10)-triene-3,16,17-triol, (16.alpha.,17.beta.)-Oestra-1,3,5(10)-triene-3,16,17-triol, Estriol [USP:INN:BAN:JAN], 3,16-.alpha.,17-.beta.-Oestriol, Estriol CRS, CAS-50-27-1, 16a-Estriol, NCGC00166111-01, 16a,17b-Estriol, Estriol, 98%, Estra-1,3,5(10)-triene-3,16,17-triol, (16a,17b)-, ESTRIOL [HSDB], Estriol, >=97%, ESTRIOL [JAN], ESTRIOL [MI], 3,16a,17b-Estriol, ESTRIOL [MART.], Prestwick0_001096, Prestwick1_001096, Prestwick2_001096, Prestwick3_001096, Estriol (JP18/USP), E0218, ESTRIOL [USP-RS], ESTRIOL [WHO-DD], Epitope ID:140131, 1,3,5(10)-Estratrien-3,16.alpha.,17.beta.-triol, Estra-1,3,5(10)-triene-3,16-.alpha., l7-.beta.-triol, SCHEMBL78033, BSPBio_001172, ESTRIOL [GREEN BOOK], (16|_,17|_)-Estra-1,3,5(10)-triene-3,16,17-triol, (16|A,17|A)-Estra-1,3,5(10)-triene-3,16,17-triol, 3,16-.alpha.,17-.beta.-Trihydroxyoestra-1,3,5(10)-triene, 4-06-00-07550 (Beilstein Handbook Reference), MLS000069812, BIDD:ER0124, SPBio_003056, ESTRIOL [EP MONOGRAPH], BPBio1_001290, CHEMBL193482, GTPL2821, ESTRIOL [USP MONOGRAPH], Estriol 1.0 mg/ml in Methanol, SCHEMBL29478427, HY-B0412R, MSK2211, HMS1571K14, HMS2090E20, HMS2098K14, HMS2234A18, HMS3715K14, HMS3884P19, Estriol for system suitability CRS, HY-B0412, Tox21_112320, Tox21_301604, BDBM50410506, EBC-11042, LMST02010003, MSK2211-100A, s2466, ESTRIOL [EMA EPAR VETERINARY], AKOS015894926, MSK2211-1000A, Tox21_112320_1, CCG-221096, DB04573, Estriol 100 microg/mL in Acetonitrile, Estriol, purum, >=97.0% (HPLC), FD12050, FE22836, SMP1_000122, NCGC00166111-02, NCGC00179277-01, NCGC00255193-01, NCGC00274080-01, (1R,2R,3aS,3bR,9bS,11aS)-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene-1,2,7-triol, AS-13735, Estriol, meets USP testing specifications, SMR000059210, SY057818, AB00514045, CS-0694816, Estriol Solution in Acetonitrile, 100ug/mL, Estriol, VETRANAL(TM), analytical standard, NS00009155, Estriol Solution in Acetonitrile, 1000ug/mL, WLN: L E5 B666TTT&J E1 FQ GQ OQ, C05141, D00185, Estra-1,3,5(10)-triene-3,16a,17b-triol, 1,3,5-ESTRATRIENE-3B,16A,17B-TRIOL, 3,16a,17b-Trihydroxyestra-1,3,5(10)-triene, 3,17.beta.-Trihydroxy-1,3,5(10)-estratriene, 3,17.beta.-Trihydroxyestra-1,3,5(10)-triene, AB00514045-08, AB00514045-09, AB00514045_10, EN300-7390799, (16.alpha.,3,5(10)-triene-3,16,17-triol, F373692, Q409721, 3,17.beta.-Trihydroxy-.delta.-1,3,5-estratriene, 3,17.beta.-Trihydroxy-.delta.-1,3,5-oestratriene, SR-01000721851-3, SR-01000721851-4, 1,5(10)-Estratriene-3,16.alpha., 17.beta.-triol, 1,5(10)-Estratriene-3,16.alpha.,17.beta.-triol, 3,16alpha,17beta-Trihydroxyestra-1,3,5(10)-triene, BRD-K17016787-001-03-5, BRD-K17016787-001-13-4, BRD-K17016787-001-16-7, Estra-1,5(10)-trien-3,16.alpha.,17.beta.-triol, Estra-1,5(10)-triene-3,16.alpha.,17.beta.-triol, 1,5-Estratriene-3.beta.,16-.alpha.,17-.beta.-triol, 1,5-Oestratriene-3-.beta.,16.alpha.,17.beta.-triol, 13b-Methyl-1,3,5(10)-gonatriene-3,16a,17b-triol, Estra-1,5(10)-trien-3,16.alpha., 17.beta.-triol, Estra-1,5(10)-triene-3,16.alpha., 17.beta.-triol, Estriol, European Pharmacopoeia (EP) Reference Standard, Oestra-1,5(10)-triene-3,16.alpha., 17.beta.-triol, Oestra-1,5(10)-triene-3,16.alpha.,17.beta.-triol, 6EC6F23B-A991-4606-8BC7-146D915DAB31, Estriol, United States Pharmacopeia (USP) Reference Standard, estra-1(10),2,4-triene-3,16,17-triol, (16alpha,17beta)-, Estra-1,5(10)-triene-3,16,17-triol, (16.alpha.,17.beta.)-, (9beta,13alpha,16beta,17beta)-estra-1(10),2,4-triene-3,16,17-triol, 13.BETA.-METHYL-1,3,5(10)-GONATRIENE-3,16.ALPHA.,17.BETA.-TRIOL, Estriol for system suitability, European Pharmacopoeia (EP) Reference Standard, (13S,16R,17R)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,16,17-triol, (8R,13S,16R,17R)-13-Methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,16,17-triol
Bioactivity: -
Solubility in Different Solvents
| Solvent | Temperature [K] | Crystal form | Solubility [mg/mL] | Reference |
|---|---|---|---|---|
| 1-Nonanol | 293.2 | - | 12.3 | [457] |
| 1-Nonanol | 298.2 | - | 14.35 | [457] |
| 1-Nonanol | 303.2 | - | 17.25 | [457] |
| 1-Nonanol | 308.2 | - | 19.18 | [457] |
| 1-Nonanol | 313.2 | - | 21.6 | [457] |
| 1-Nonanol | 318.2 | - | 24.17 | [457] |
| 1-Nonanol | 323.2 | - | 27.56 | [457] |
| 1-Nonanol | 328.2 | - | 32.6 | [457] |
| 1-Octanol | 293.2 | - | 10.9 | [457] |
| 1-Octanol | 298.2 | - | 12.42 | [457] |
| 1-Octanol | 303.2 | - | 13.63 | [457] |
| 1-Octanol | 308.2 | - | 15.79 | [457] |
| 1-Octanol | 313.2 | - | 18.87 | [457] |
| 1-Octanol | 318.2 | - | 21.89 | [457] |
| 1-Octanol | 323.2 | - | 26.55 | [457] |
| 1-Octanol | 328.2 | - | 30.82 | [457] |
| 1-Pentanol | 293.2 | - | 6.492 | [457] |
| 1-Pentanol | 298.2 | - | 7.583 | [457] |
| 1-Pentanol | 303.2 | - | 9.729 | [457] |
| 1-Pentanol | 308.2 | - | 12.36 | [457] |
| 1-Pentanol | 313.2 | - | 15.64 | [457] |
| 1-Pentanol | 318.2 | - | 21.25 | [457] |
| 1-Pentanol | 323.2 | - | 25.32 | [457] |
| 1-Pentanol | 328.2 | - | 31.61 | [457] |
| 2-Butanol | 293.2 | - | 5.942 | [457] |
| 2-Butanol | 298.2 | - | 7.82 | [457] |
| 2-Butanol | 303.2 | - | 9.96 | [457] |
| 2-Butanol | 308.2 | - | 12.49 | [457] |
| 2-Butanol | 313.2 | - | 13.97 | [457] |
| 2-Butanol | 318.2 | - | 16.36 | [457] |
| 2-Butanol | 323.2 | - | 20.42 | [457] |
| 2-Butanol | 328.2 | - | 24.72 | [457] |
| Dimethylformamide | 293.2 | - | 4.197 | [457] |
| Dimethylformamide | 298.2 | - | 5.894 | [457] |
| Dimethylformamide | 303.2 | - | 9.584 | [457] |
| Dimethylformamide | 308.2 | - | 15.77 | [457] |
| Dimethylformamide | 313.2 | - | 21.43 | [457] |
| Dimethylformamide | 318.2 | - | 35.29 | [457] |
| Dimethylformamide | 323.2 | - | 47.8 | [457] |
| Dimethylformamide | 328.2 | - | 66.2 | [457] |
| Dodecane | 293.2 | - | 0.9142 | [457] |
| Dodecane | 298.2 | - | 0.9843 | [457] |
| Dodecane | 303.2 | - | 1.16 | [457] |
| Dodecane | 308.2 | - | 1.196 | [457] |
| Dodecane | 313.2 | - | 1.594 | [457] |
| Dodecane | 318.2 | - | 2.219 | [457] |
| Dodecane | 323.2 | - | 2.999 | [457] |
| Dodecane | 328.2 | - | 3.501 | [457] |
| N-Methyl-2-pyrrolidone | 293.2 | - | 1.248 | [457] |
| N-Methyl-2-pyrrolidone | 298.2 | - | 2.027 | [457] |
| N-Methyl-2-pyrrolidone | 303.2 | - | 3.131 | [457] |
| N-Methyl-2-pyrrolidone | 308.2 | - | 5.17 | [457] |
| N-Methyl-2-pyrrolidone | 313.2 | - | 8.143 | [457] |
| N-Methyl-2-pyrrolidone | 318.2 | - | 10.74 | [457] |
| N-Methyl-2-pyrrolidone | 323.2 | - | 14.44 | [457] |
| N-Methyl-2-pyrrolidone | 328.2 | - | 21.07 | [457] |
| Octane | 293.2 | - | 1.102 | [457] |
| Octane | 298.2 | - | 1.297 | [457] |
| Octane | 303.2 | - | 1.532 | [457] |
| Octane | 308.2 | - | 1.797 | [457] |
| Octane | 313.2 | - | 2.134 | [457] |
| Octane | 318.2 | - | 2.38 | [457] |
| Octane | 323.2 | - | 2.606 | [457] |
| Octane | 328.2 | - | 3.171 | [457] |
| Water | 293.2 | - | 1.838 | [457] |
| Water | 298.2 | - | 2.153 | [457] |
| Water | 303.2 | - | 2.673 | [457] |
| Water | 308.2 | - | 3.033 | [457] |
| Water | 313.2 | - | 4.849 | [457] |
| Water | 318.2 | - | 6.673 | [457] |
| Water | 323.2 | - | 9.105 | [457] |
| Water | 328.2 | - | 12.65 | [457] |
Molecule 3D descriptors
| Descriptor | Value |
|---|---|
| PMI1 | 600.2239 |
| PMI2 | 3312.6813 |
| PMI3 | 3708.5600 |
| NPR1 | 0.1618 |
| NPR2 | 0.8933 |
| RadiusOfGyration | 3.6351 |
| InertialShapeFactor | 0.0015 |
| Eccentricity | 0.9868 |
| Asphericity | 0.5914 |
| SpherocityIndex | 0.1913 |
| PBF | 0.6971 |